Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Pedro A Piedra"'
Autor:
Jiani Chen, Swan Tan, Vasanthi Avadhanula, Leonard Moise, Pedro A Piedra, Anne S De Groot, Justin Bahl
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010360 (2023)
Human respiratory syncytial virus (RSV) is a major cause of lower respiratory infection. Despite more than 60 years of research, there is no licensed vaccine. While B cell response is a major focus for vaccine design, the T cell epitope profile of RS
Externí odkaz:
https://doaj.org/article/425eb1f32a3c495e9b17ae9d594b72c4
Autor:
Harsha Doddapaneni, Sara Javornik Cregeen, Richard Sucgang, Qingchang Meng, Xiang Qin, Vasanthi Avadhanula, Hsu Chao, Vipin Menon, Erin Nicholson, David Henke, Felipe-Andres Piedra, Anubama Rajan, Zeineen Momin, Kavya Kottapalli, Kristi L Hoffman, Fritz J Sedlazeck, Ginger Metcalf, Pedro A Piedra, Donna M Muzny, Joseph F Petrosino, Richard A Gibbs
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0244468 (2021)
The newly emerged and rapidly spreading SARS-CoV-2 causes coronavirus disease 2019 (COVID-19). To facilitate a deeper understanding of the viral biology we developed a capture sequencing methodology to generate SARS-CoV-2 genomic and transcriptome se
Externí odkaz:
https://doaj.org/article/fbdf2fda1398487d93140df8ceeaf947
Autor:
Felipe-Andrés Piedra, Xueting Qiu, Michael N Teng, Vasanthi Avadhanula, Annette A Machado, Do-Kyun Kim, James Hixson, Justin Bahl, Pedro A Piedra
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227558 (2020)
Respiratory syncytial virus (RSV) is a nonsegmented negative-strand RNA virus (NSV) and a leading cause of severe lower respiratory tract illness in infants and the elderly. Transcription of the ten RSV genes proceeds sequentially from the 3' promote
Externí odkaz:
https://doaj.org/article/2c663f3b43f74bffaffc508273adcccd
Autor:
Felipe-Andrés Piedra, Minghua Mei, Vasanthi Avadhanula, Reena Mehta, Letisha Aideyan, Roberto P Garofalo, Pedro A Piedra
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172953 (2017)
Respiratory syncytial virus (RSV) causes significant infant morbidity and mortality. For decades severe RSV-induced disease was thought to result from an uncontrolled host response to viral replication, but recent work suggests that a strong innate i
Externí odkaz:
https://doaj.org/article/44f0b76e383f4619904f3d4b63cd2b25
Autor:
Anne M Hause, David M Henke, Vasanthi Avadhanula, Chad A Shaw, Lorena I Tapia, Pedro A Piedra
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175792 (2017)
The fusion (F) protein of RSV is the major vaccine target. This protein undergoes a conformational change from pre-fusion to post-fusion. Both conformations share antigenic sites II and IV. Pre-fusion F has unique antigenic sites p27, ø, α2α3β3β
Externí odkaz:
https://doaj.org/article/f1e05607da284d0f87cc43a69433f3a0
Autor:
Anne M Hause, David M Henke, Vasanthi Avadhanula, Chad A Shaw, Lorena I Tapia, Pedro A Piedra
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180623 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0175792.].
Externí odkaz:
https://doaj.org/article/027db7d785df45cfaf1a33a12e20ceed
Autor:
Lorena I Tapia, Chad A Shaw, Letisha O Aideyan, Alan M Jewell, Brian C Dawson, Taha R Haq, Pedro A Piedra
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90786 (2014)
Human respiratory syncytial virus (HRSV) has three surface glycoproteins: small hydrophobic (SH), attachment (G) and fusion (F), encoded by three consecutive genes (SH-G-F). A 270-nt fragment of the G gene is used to genotype HRSV isolates. This stud
Externí odkaz:
https://doaj.org/article/f1db80d268c5479094e37172ae57339d
Autor:
Sarah E Blutt, David O Matson, Sue E Crawford, Mary Allen Staat, Parvin Azimi, Berkeley L Bennett, Pedro A Piedra, Margaret E Conner
Publikováno v:
PLoS Medicine, Vol 4, Iss 4, p e121 (2007)
BackgroundAntigenemia is commonly detected in rotavirus-infected children. Although rotavirus RNA has been detected in serum, definitive proof of rotavirus viremia has not been shown. We aimed to analyze a defined patient population to determine if i
Externí odkaz:
https://doaj.org/article/d6490f598ea446ada77d89a43a80b7d6
Autor:
Brittani N. Blunck, Laura S. Angelo, David Henke, Vasanthi Avadhanula, Matthew Cusick, Laura Ferlic-Stark, Lynn Zechiedrich, Brian E. Gilbert, Pedro A. Piedra
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Respiratory Syncytial Virus (RSV) is ubiquitous and re-infection with both subtypes (RSV/A and RSV/B) is common. The fusion (F) protein of RSV is antigenically conserved, induces neutralizing antibodies, and is a primary target of vaccine development
Externí odkaz:
https://doaj.org/article/71e0730d4f5c42b4b67fcc9c1f0f0944
Autor:
Xavier Carbonell-Estrany, Eric AF Simões, Louis J Bont, Bosco A Paes, Adaeze Ayuk, Angela Gentile, Anne Greenough, Antonio Moreno, Arun Sharma, Asuncion Mejias, Barry Rodgers-Gray, Bernhard Resch, Brigette Fauroux, Carlos E Rodriguez-Martinez, Chadi El Saleeby, W Charles Huskins, Cheryl Cohen, David Greenberg, Eugenio Baraldi, Evan Anderson, Federico Martinon Torres, Fernando F Polack, Giovanni Piedimonte, Harish Nair, Hayley Gans, Heather J Zar, Hiroyuki Moriuchi, Hitoshi Oshitani, Ian Mitchell, D James Nokes, Jarju Sheikh, Jeffrey Pernica, Jesse Papenburg, Joan Robinson, Joanne De Jesus-Cornejo, Joanne Langley, Johannes Liese, Jose Figueras Aloy, Juan Pablo Torres Torretti, Kathryn Edwards, Leonard Krilov, Maduja Divaratne, Manuel Sanchez Luna, Marcello Lanari, Marcelo Scotta, Maria Garba, Masaaki Mori, Merih Cetinkaya, Mitchell Goldstein, Najwa Khuri-Bulos, Nestor E Vain, Nikolaos Papadopoulus, Nusrat Homaira, Octavio Ramilo, Paolo Manzoni, Patrick Munywoki, Pedro A Piedra, Peter Moschovis, Peter Openshaw, Quique Bassat, Renato Stein, Richard Thwaites, Rohitha Muthugala, Rolando Ulloa-Gutierrez, Ron Dagan, Rosa Rodriguez Fernandez, Satoshi Kusuda, Shabir Madhi, Shobha Broor, Simon B Drysdale, Sudha Basnet, Terho Heikkinen, Vasanthi Avadhanula, Xavier Saez-Llorens, Xin Wang, You Li, Joseph L Mathew
Publikováno v:
The Lancet Global Health. 11:e655-e657