Výsledky vyhledávání - "Pedro A C Costa"

Akademický článek

The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria.

Autor: Lis R V Antonelli, Fabiana M S Leoratti, Pedro A C Costa, Bruno C Rocha, Suelen Q Diniz, Mauro S Tada, Dhelio B Pereira, Andrea Teixeira-Carvalho, Douglas T Golenbock, Ricardo Gonçalves, Ricardo T Gazzinelli

Publikováno v: PLoS Pathogens, Vol 10, Iss 9, p e1004393 (2014)

Infection with Plasmodium vivax results in strong activation of monocytes, which are important components of both the systemic inflammatory response and parasite control. The overall goal of this study was to define the role of monocytes during P. vi

Externí odkaz: https://doaj.org/article/05a4ed5d79314833a4fcbc7784395f4d

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Akademický článek

E3 Ubiquitin Ligase Smurf1 Regulates the Inflammatory Response in Macrophages and Attenuates Hepatic Damage during Betacoronavirus Infection

Autor: Luiz P. Souza-Costa, Felipe R. S. Santos, Jordane C. Pimenta, Celso M. Queiroz-Junior, Fernanda L. Tana, Danielle C. Teixeira, Manoela G. G. Couto, Natalia F. M. Oliveira, Rafaela D. Pereira, Vinicius A. Beltrami, Pedro A. C. Costa, Larisse S. B. Lacerda, Josiane T. Andrade-Chaves, Pedro P. G. Guimarães, Renato S. Aguiar, Mauro M. Teixeira, Vivian V. Costa, Luis H. Franco

Publikováno v: Pathogens, Vol 13, Iss 10, p 871 (2024)

The E3 ubiquitin ligase Smurf1 catalyzes the ubiquitination and proteasomal degradation of several protein substrates related to inflammatory responses and antiviral signaling. This study investigated the role of Smurf1 in modulating inflammation ind

Externí odkaz: https://doaj.org/article/cd66f239cf834ae495ed73b4154dfa0b

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Akademický článek

Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression

Autor: Pedro A. C. Costa, Walison N. Silva, Pedro H. D. M. Prazeres, Caroline C. Picoli, Gabriela D. A. Guardia, Alinne C. Costa, Mariana A. Oliveira, Pedro P. G. Guimarães, Ricardo Gonçalves, Mauro C. X. Pinto, Jaime H. Amorim, Vasco A. C. Azevedo, Rodrigo R. Resende, Remo C. Russo, Thiago M. Cunha, Pedro A. F. Galante, Akiva Mintz, Alexander Birbrair

Publikováno v: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-41 (2021)

Abstract Sensory neurons have recently emerged as components of the tumor microenvironment. Nevertheless, whether sensory neuronal activity is important for tumor progression remains unknown. Here we used Designer Receptors Exclusively Activated by a

Externí odkaz: https://doaj.org/article/3bc21826b70242beab95f440ca474ea2

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Akademický článek

Toxoplasma gondii-Induced Neutrophil Extracellular Traps Amplify the Innate and Adaptive Response

Autor: Farlen J. B. Miranda, Bruno C. Rocha, Milton C. A. Pereira, Larissa M. N. Pereira, Erikson H. M. de Souza, Ana P. Marino, Pedro A. C. Costa, Daniel V. Vasconcelos-Santos, Lis R. V. Antonelli, Ricardo T. Gazzinelli

Publikováno v: mBio, Vol 12, Iss 5 (2021)

Approximately one-third of the human population is estimated to be chronically infected with the obligate intracellular parasite Toxoplasma gondiiT. gondii

Externí odkaz: https://doaj.org/article/a253a751d6e84d1582b0b6754e1e5f8a

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Akademický článek

Direct Power Control of a Single Stage Current Source Inverter Grid-Tied PV System

Autor: Erhab Youssef, Pedro B. C. Costa, Sonia F. Pinto, Amr Amin, Adel A. El Samahy

Publikováno v: Energies, Vol 13, Iss 12, p 3165 (2020)

In this paper, a direct power predictive controller (DPPC) is derived for a current source inverter (CSI) based single stage photovoltaic (PV) system. The equations of the dynamics, including AC and DC filters, are formulated directly for the PV powe

Externí odkaz: https://doaj.org/article/e47d8f595b23418bbf2b1ef1ecea9804

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Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression

Autor: Walison N. Silva, Pedro A. F. Galante, Ricardo Gonçalves, Gabriela D A Guardia, Caroline C. Picoli, Mauro Cunha Xavier Pinto, Alexander Birbrair, Vasco Azevedo, Pedro A C Costa, Thiago M. Cunha, Rodrigo R. Resende, Alinne C. Costa, Pedro P.G. Guimarães, Akiva Mintz, Pedro H.D.M. Prazeres, Mariana Assíria de Oliveira, Remo Castro Russo, Jaime Henrique Amorim

Publikováno v: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-41 (2021)
Acta Neuropathologica Communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Sensory neurons have recently emerged as components of the tumor microenvironment. Nevertheless, whether sensory neuronal activity is important for tumor progression remains unknown. Here we used Designer Receptors Exclusively Activated by a Designer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd172e6c3570d7863975697de93297c
https://doaj.org/article/3bc21826b70242beab95f440ca474ea2

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C(3)1-TAg in C57BL/6 J background as a model to study mammary tumor development

Autor: Akiva Mintz, Caroline C. Picoli, Leda M.C. Coimbra-Campos, Maryam Soltani-asl, Vasco Azevedo, Rodrigo R. Resende, Debora Heller, Bryan Ôrtero Perez Gonçalves, Pedro A C Costa, Walison N. Silva, Gabryella S P Santos, Isadora F. G. Sena, Mauro Cunha Xavier Pinto, Alexander Birbrair, Beatriz G S Rocha, Geovanni Dantas Cassali, Ana Paula Vargas Garcia, Alinne C. Costa, Jaime Henrique Amorim

Publikováno v: Histochemistry and Cell Biology. 156:165-182

Diagnosis and prognosis of breast cancer is based on disease staging identified through histopathological and molecular biology techniques. Animal models are used to gain mechanistic insights into the development of breast cancer. C(3)1-TAg is a gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45462439acf9804ae4aa9e7dbf00a1a0
https://doi.org/10.1007/s00418-021-01995-w

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Circulating Nestin-GFP+ Cells Participate in the Pathogenesis of Paracoccidioides brasiliensis in the Lungs

Autor: Mauro Cunha Xavier Pinto, Pedro A C Costa, Caroline C. Picoli, Danielle G. Souza, Ludmila Matos Baltazar, Fabrício Marcus Silva Oliveira, Remo Castro Russo, Vasco Azevedo, Rodrigo R. Resende, Alinne C. Costa, Walison N. Silva, Gabryella S P Santos, Jaime Henrique Amorim, Alexander Birbrair, Akiva Mintz, Leda M.C. Coimbra-Campos, Pedro H.D.M. Prazeres, Beatriz G S Rocha

Publikováno v: Stem Cell Reviews and Reports. 17:1874-1888

Multiple infectious diseases lead to impaired lung function. Revealing the cellular mechanisms involved in this impairment is crucial for the understanding of how the lungs shift from a physiologic to a pathologic state in each specific condition. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cf0ab2fdce5409ad7b880e23254f7cb
https://doi.org/10.1007/s12015-021-10181-3

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Sensory nerves in the spotlight of the stem cell niche

Autor: Alexander Birbrair, Thiago M. Cunha, Rodrigo R. Resende, Pedro H.D.M. Prazeres, Beatriz G S Rocha, Anderson Oropeza, Pedro A C Costa, Vasco Azevedo, Akiva Mintz, Walison N. Silva, Gabryella S P Santos, Caroline C. Picoli, Rodrigo A. da Silva, Alinne C. Costa

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 346-356 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cbca69a3d5dbadd99f09aab09bb106
http://europepmc.org/articles/PMC7900586

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