Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Pedro Tranque"'
Autor:
Juan-Manuel Bonet-Fernández, Pedro Tranque, Jose Daniel Aroca-Aguilar, Luis J. Muñoz, Dolores E. López, Julio Escribano, Carlos de Cabo
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe balance between the activity of the Na+/K+/Cl− cotransporter (NKCC1) that introduces Cl− into the cell and the K+/Cl− cotransporter (KCC2) that transports Cl− outside the cell is critical in determining the inhibitory or excitat
Externí odkaz:
https://doaj.org/article/f4de0f8df4ef487187944caf20cdd54f
Publikováno v:
IBRO Reports, Vol 8, Iss , Pp 36-47 (2020)
The technical difficulty to isolate microglia, astrocytes and infiltrating immune cells from mouse brain is nowadays a limiting factor in the study of neuroinflammation. Brain isolation requirements are cell-type and animal-age dependent, but current
Externí odkaz:
https://doaj.org/article/7cb306765c89482fb798ec8a3dcc0059
Publikováno v:
International journal of molecular sciences. 24(1)
The inhibition of Glycogen Synthase Kinase 3 β (GSK3β) by Ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::090f6946875d92f4351c33418678722d
https://pubmed.ncbi.nlm.nih.gov/36613781
https://pubmed.ncbi.nlm.nih.gov/36613781
Publikováno v:
IBRO Reports, Vol 8, Iss, Pp 36-47 (2020)
IBRO Reports
IBRO Reports
Highlights • Recovery of neural cells is higher with 30 % Percoll gradient than 30–70 %. • Papain enhances combined extraction of microglia, astrocytes and lymphocytes. • Dispase II potentiates papain action only in adult brain. • Mechanica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b03e996d9351c6597aaf0f60d6e635
https://doi.org/10.1016/j.ibror.2019.12.004
https://doi.org/10.1016/j.ibror.2019.12.004
Publikováno v:
Molecular neurobiology. 58(2)
GSK3β is a constitutively active kinase that promotes cell death, which requires strict regulatory mechanisms. Although Akt-mediated phosphorylation at Ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc86fab9874eb859403f8d748d454766
https://pubmed.ncbi.nlm.nih.gov/33029741
https://pubmed.ncbi.nlm.nih.gov/33029741
Autor:
Almudena Ruiz-García, María José Díaz-Guerra, Susana López-López, Jorge Laborda, Pedro Tranque, Susana Mellado, Eva M. Monsalve, José J. García-Ramírez, Elena Caminos, Miriam Fernández
Publikováno v:
European Journal of Immunology. 47:2090-2100
Inhibition of Notch signalling in T cells attenuates the development of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Growing evidence indicates that myeloid cells are also key players in autoimmune processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ee57a86f1c9cd0e2ea8ad6455ea210
https://doi.org/10.1002/eji.201646901
https://doi.org/10.1002/eji.201646901
Autor:
Carmen Gómez-Roldán, Juan Pérez-Martínez, Abraham J. Domb, Shady Farah, Nurit Beyth, Syong H. Nam-Cha, Francisco C. Pérez-Martínez, Pedro Tranque, Ana V. Ocaña, Ramón Pérez-Tanoira, Agustín Ortega
Publikováno v:
IET Nanobiotechnology. 9:342-348
Peritonitis is a disease caused by bacterial strains that have become increasingly resistant to many antibiotics. The development of alternative therapeutic compounds is the focus of extensive research, so novel nanoparticles (NPs) with activity agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9968866722b0a3ad3bcb117231a35eb4
https://doi.org/10.1049/iet-nbt.2014.0078
https://doi.org/10.1049/iet-nbt.2014.0078
Autor:
Pedro Tranque, Eva Cano, María C. Serrano-Pérez, Miriam Fernández, Mónica Berjón-Otero, Fernando Neria, Ernesto Doncel-Pérez
Publikováno v:
Glia. 63:987-1004
The study of factors that regulate the survival, proliferation, and differentiation of neural precursor cells (NPCs) is essential to understand neural development as well as brain regeneration. The Nuclear Factor of Activated T Cells (NFAT) is a fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d087e53444d3b02d8244dca82b60a81
https://doi.org/10.1002/glia.22797
https://doi.org/10.1002/glia.22797
Autor:
María C. Serrano-Pérez, Fernando Neria, Pedro Tranque, Eva Cano, Katia Urso, Patricia Velasco
Publikováno v:
Glia. 61:1052-1066
Increase in intracellular calcium ([Ca(2+) ]i ) is a key mediator of astrocyte signaling, important for activation of the calcineurin (CN)/nuclear factor of activated T cells (NFAT) pathway, a central mediator of inflammatory events. We analyzed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddbf8178220f30abbd6f21173c0f81a9
https://doi.org/10.1002/glia.22494
https://doi.org/10.1002/glia.22494
Publikováno v:
Glia. 59:959-972
Selenoprotein S (SelS) is an endoplasmic reticulum (ER)-resident protein involved in the unfolded protein response. Besides reducing ER-stress, SelS attenuates inflammation by decreasing pro-inflammatory cytokines. We have recently shown that SelS is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c097f1dd993b117e0f027428685f72
https://doi.org/10.1002/glia.21168
https://doi.org/10.1002/glia.21168