Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Pedro Lei"'
Autor:
Juan José León, Nía Oetiker, Nicolás Torres, Nicolás Bruna, Evgenii Oskolkov, Pedro Lei, Andrey N. Kuzmin, Kaiwen Chen, Stelios Andreadis, Blaine A. Pfeifer, Mark T. Swihart, Paras N. Prasad, José Pérez-Donoso
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Rare-earth sulfide nanoparticles (NPs) could harness the optical and magnetic features of rare-earth ions for applications in nanotechnology. However, reports of their synthesis are scarce and typically require high temperatures a
Externí odkaz:
https://doaj.org/article/fb63ec1fb7fb4f338f691ecd78ab441a
Autor:
Samantha E. Cassel, Breanna M. Huntington, Wilfred Chen, Pedro Lei, Stelios T. Andreadis, April M. Kloxin
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026127-026127-17 (2024)
Activation of fibroblasts is pivotal for wound healing; however, persistent activation leads to maladaptive processes and is a hallmark of fibrosis, where disease mechanisms are only partially understood. Human in vitro model systems complement in vi
Externí odkaz:
https://doaj.org/article/cb5866edd5e14cf7bca82c5be176521e
Autor:
Yayu Liu, Pedro Lei, Ronel Z. Samuel, Anagha M. Kashyap, Theodore Groth, Wiam Bshara, Sriram Neelamegham, Stelios T. Andreadis
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2056-2073 (2023)
During epithelial–mesenchymal transition (EMT) in cancer progression, tumor cells switch cadherin profile from E‐cadherin to cadherin‐11 (CDH11), which is accompanied by increased invasiveness and metastatic activity. However, the mechanism thr
Externí odkaz:
https://doaj.org/article/61a8c0a37da6437793ec0e2602e16bc1
Autor:
Debanik Choudhury, Na Rong, Hamsa Vardini Senthil Kumar, Sydney Swedick, Ronel Z. Samuel, Pihu Mehrotra, John Toftegaard, Nika Rajabian, Ramkumar Thiyagarajan, Ashis K. Podder, Yulun Wu, Shahryar Shahini, Kenneth L. Seldeen, Bruce Troen, Pedro Lei, Stelios T. Andreadis
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113738- (2024)
Summary: Mitochondrial dysfunction is a hallmark of cellular senescence, with the loss of mitochondrial function identified as a potential causal factor contributing to senescence-associated decline in cellular functions. Our recent findings revealed
Externí odkaz:
https://doaj.org/article/7e0989fdc4cd4210b9b77af2703db105
Autor:
Kihoon Nam, Harim T. dos Santos, Frank Maslow, Bryan G. Trump, Pedro Lei, Stelios T. Andreadis, Olga J. Baker
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Previous studies demonstrated that salivary gland morphogenesis and differentiation are enhanced by modification of fibrin hydrogels chemically conjugated to Laminin-1 peptides. Specifically, Laminin-1 peptides (A99: CGGALRGDN-amide and YIGSR: CGGADP
Externí odkaz:
https://doaj.org/article/f0293570a237419ca7d067fb40a5b3ff
Autor:
Aref Shahini, Kalyan Vydiam, Debanik Choudhury, Nika Rajabian, Thy Nguyen, Pedro Lei, Stelios T. Andreadis
Publikováno v:
Stem Cell Research, Vol 30, Iss , Pp 122-129 (2018)
Skeletal muscle (SkM) regeneration relies on the activity of myogenic progenitors that reside beneath the basal lamina of myofibers. Here, we describe a protocol for the isolation of the SkM progenitors from young and old mice by exploiting their out
Externí odkaz:
https://doaj.org/article/1bb73be2c25f4a04b72555be43c74f98
Autor:
Aref Shahini, Debanik Choudhury, Mohammadnabi Asmani, Ruogang Zhao, Pedro Lei, Stelios T. Andreadis
Publikováno v:
Stem Cell Research, Vol 26, Iss , Pp 55-66 (2018)
Adult skeletal muscle regeneration relies on the activity of satellite cells residing in the skeletal muscle niche. However, systemic and intrinsic factors decrease the myogenic differentiation potential of satellite cells thereby impairing muscle re
Externí odkaz:
https://doaj.org/article/213eb98871254a39bc6a74f014933ab8
Autor:
Amin Jafari, Nika Rajabian, Guojian Zhang, Mohamed Alaa Mohamed, Pedro Lei, Stelios T. Andreadis, Blaine A. Pfeifer, Chong Cheng
Publikováno v:
Materials, Vol 13, Iss 4, p 898 (2020)
As a promising strategy for the treatment of various diseases, gene therapy has attracted increasing attention over the past decade. Among various gene delivery approaches, non-viral vectors made of synthetic biomaterials have shown significant poten
Externí odkaz:
https://doaj.org/article/c2d425a76c0d48f69b89ac346e925453
Autor:
Pihu Mehrotra, Izuagie Ikhapoh, Pedro Lei, Georgios Tseropoulos, Yali Zhang, Jianmin Wang, Song Liu, Marianne E Bronner, Stelios T Andreadis
Publikováno v:
Stem cells (Dayton, Ohio).
Neural crest-like stem cells resembling embryonic neural crest cells (NCs) can be derived from adult human tissues such as the epidermis. However, these cells lose their multipotency rapidly in culture limiting their expansion for clinical use. Here,
Autor:
Kihoon Nam, Christina L Maruyama, Ching-Shuen Wang, Bryan G Trump, Pedro Lei, Stelios T Andreadis, Olga J Baker
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187069 (2017)
Hyposalivation reduces the patient quality of life, as saliva is important for maintaining oral health. Current treatments for hyposalivation are limited to medications such as the muscarinic receptor agonists, pilocarpine and cevimeline. However, th
Externí odkaz:
https://doaj.org/article/2043e9fb5fa6498e9bc39dd5a5ddce6a