Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Pedro, Casado"'
Autor:
Pedro Casado, Ana Rio-Machin, Juho J. Miettinen, Findlay Bewicke-Copley, Kevin Rouault-Pierre, Szilvia Krizsan, Alun Parsons, Vinothini Rajeeve, Farideh Miraki-Moud, David C. Taussig, Csaba Bödör, John Gribben, Caroline Heckman, Jude Fitzgibbon, Pedro R. Cutillas
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Acute myeloid leukaemia (AML) patients harbouring certain chromosome abnormalities have particularly adverse prognosis. For these patients, targeted therapies have not yet made a significant clinical impact. To understand the molecular lands
Externí odkaz:
https://doaj.org/article/5e487f8d5d7f4d8e866dad9751eee848
Autor:
William Grey, Samantha Atkinson, Beatrice Rix, Pedro Casado, Linda Ariza-McNaughton, Cathy Hawley, Miriam L. Sopoena, Katherine S. Bridge, David Kent, Pedro R. Cutillas, Dominique Bonnet
Publikováno v:
HemaSphere, Vol 7, Iss 3, p e853 (2023)
Long-term hematopoietic stem cells are rare, highly quiescent stem cells of the hematopoietic system with life-long self-renewal potential and the ability to transplant and reconstitute the entire hematopoietic system of conditioned recipients. Most
Externí odkaz:
https://doaj.org/article/4e0fa0757b774e4ca29813340f26d393
Autor:
Kathryn Davidson, Paul Grevitt, Maria F. Contreras-Gerenas, Katherine S. Bridge, Miguel Hermida, Kunal M. Shah, Faraz K. Mardakheh, Mark Stubbs, Rosemary Burke, Pedro Casado, Pedro R. Cutillas, Sarah A. Martin, Tyson V. Sharp
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Abstract An early event in lung oncogenesis is loss of the tumour suppressor gene LIMD1 (LIM domains containing 1); this encodes a scaffold protein, which suppresses tumorigenesis via a number of different mechanisms. Approximately 45% of non-small c
Externí odkaz:
https://doaj.org/article/006a5cc989ef440e83fa93a4ded65708
Autor:
Angelica Gualtieri, Nikolina Kyprianou, Louise C. Gregory, Maria Lillina Vignola, James G. Nicholson, Rachael Tan, Shin-ichi Inoue, Valeria Scagliotti, Pedro Casado, James Blackburn, Fernando Abollo-Jimenez, Eugenia Marinelli, Rachael E. J. Besser, Wolfgang Högler, I. Karen Temple, Justin H. Davies, Andrey Gagunashvili, Iain C.A.F. Robinson, Sally A. Camper, Shannon W. Davis, Pedro R. Cutillas, Evelien F. Gevers, Yoko Aoki, Mehul T. Dattani, Carles Gaston-Massuet
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Mutations in components of the MAP kinase pathway are associated with a group of syndromes known as RASopathies. Here, the authors identify gain-of-function mutations in BRAF in patients with RASopathies and congenital hypopituitarisms. This article
Externí odkaz:
https://doaj.org/article/e3eb9cf575fa459d8daff6264b919278
Autor:
Henry Gerdes, Pedro Casado, Arran Dokal, Maruan Hijazi, Nosheen Akhtar, Ruth Osuntola, Vinothini Rajeeve, Jude Fitzgibbon, Jon Travers, David Britton, Shirin Khorsandi, Pedro R. Cutillas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Artificial intelligence and machine learning promise to transform cancer therapies by accurately predicting the most appropriate drugs to treat individual patients. Here, the authors present an approach which uses omics data to produce ordered lists
Externí odkaz:
https://doaj.org/article/dd9e23dc4fd245f6935c304010512356
Autor:
Emilia Roy-Vallejo, Laura Cardeñoso, Ana Triguero-Martínez, Marta Chicot Llano, Nelly Zurita, Elena Ávalos, Ana Barrios, Julia Hernando, Javier Ortiz, Sebastián C. Rodríguez-García, Marianela Ciudad Sañudo, Celeste Marcos, Elena García Castillo, Leticia Fontán García-Rodrigo, Begoña González, Rosa Méndez, Isabel Iturrate, Ancor Sanz-García, Almudena Villa, Ana Sánchez-Azofra, Begoña Quicios, David Arribas, Jesús Álvarez Rodríguez, Pablo Patiño, Marina Trigueros, Miren Uriarte, Alexandra Martín-Ramírez, Cristina Arévalo Román, José María Galván-Román, Rosario García-Vicuña, Julio Ancochea, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Rafael de la Cámara, Carmen Suárez Fernández, Isidoro González-Álvaro, Diego A. Rodríguez-Serrano, the PREDINMUN-COVID Group, Jesús Sanz, Pedro Casado, Ángela Gutiérrez, Azucena Bautista, Pilar Hernández, Nuria Ruiz Giménez, Berta Moyano, Paloma Gil, María Jesús Delgado, Pedro Parra, Beatriz Sánchez, Carmen Sáez, Marta Fernández Rico, Diego Domingo García, Teresa Alarcón Cavero, María Auxiliadora Semiglia Chong, Ainhoa Gutiérrez Cobos, Santos Castañeda, Irene Llorente, Eva G. Tomero, Noelia García Castañeda, Nuria Montes, Cristina Dominguez Peña, David Jiménez Jiménez, Pablo Villamayor, Alfonso Canabal, Tamara Alonso, Carolina Cisneros, Claudia Valenzuela, Francisco Javier García Pérez, Rosa María Girón, Javier Aspa, M. del Perpetuo Socorro Churruca, Enrique Zamora, Adrián Martínez, Mar Barrio Mayo, Rosalina Henares Espi, Francisco Sánchez-Madrid, Enrique Martín Gayo, Ildefonso Sánchez-Cerrillo, Ana Marcos Jimenez, Pedro Martínez-Fleta, Celia López-Sanz, Ligia Gabrie, Luciana del Campo Guerola, Reyes Tejedor, Rosa Carracedo Rodríguez
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundInterleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not been assessed in a prospective cohort. Our aim was to evaluate the relationship between SARS-CoV-2
Externí odkaz:
https://doaj.org/article/2e8c5c8c3fe4433d9e6a941239aec30c
Autor:
Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S. H. Costa, Pedro Casado, Beatriz de Luxan Delgado, Louise E. Reynolds, Jesus Gomez-Escudero, Emma Newport, Vinothini Rajeeve, Ann-Marie Baker, Marina Roy-Luzarraga, Trevor A. Graham, Julie Foster, Yu Wang, James J. Campbell, Rajinder Singh, Penglie Zhang, Thomas J. Schall, Frances R. Balkwill, Jane Sosabowski, Pedro R. Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala-Dilke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Cancer associated fibroblasts (CAFs) have been suggested to regulate cancer cell metabolism, but the mechanisms are not completely elucidated. Here, the authors show that low FAK expression in stromal cells correlates with poor prognosis in breast an
Externí odkaz:
https://doaj.org/article/514da35f7c834a7f879f285d226a9e53
Akademický článek
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Autor:
Cecilia Mouronte-Roibás, Virginia Leiro-Fernández, Alberto Ruano-Raviña, Cristina Ramos-Hernández, Pedro Casado-Rey, Maribel Botana-Rial, Esmeralda García-Rodríguez, Alberto Fernández-Villar
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background There is a relationship between Chronic Obstructive Pulmonary Disease (COPD) and the development of lung cancer (LC). The aim of this study is to analyse several blood markers and compare their concentrations in patients with only
Externí odkaz:
https://doaj.org/article/27bd33a1566e48ea863490ed8f3bacaa
Autor:
Pedro Casado-Rey, Lorena Vázquez-Iglesias, Maribel Botana-Rial, María Amalia Andrade-Olivié, Lucía Ferreiro-Fernández, Esther San José Capilla, Ana Nuñez-Ares, Elena Bollo de Miguel, Virginia Pajares-Ruíz, Alberto Fernández-Villar
Publikováno v:
PLoS ONE, Vol 16, Iss 6 (2021)
In previous studies, measuring the levels of calprotectin in patients with pleural effusion (PE) was an exceptionally accurate way to predict malignancy. Here, we evaluated a rapid method for the measurement of calprotectin levels as a useful paramet
Externí odkaz:
https://doaj.org/article/a3e6c08bb08b4990983f60c4bd9860e8