Zobrazeno 1 - 10
of 455
pro vyhledávání: '"Pedram Argani"'
Autor:
Kaushal Asrani, Juhyung Woo, Adrianna A. Mendes, Ethan Schaffer, Thiago Vidotto, Clarence Rachel Villanueva, Kewen Feng, Lia Oliveira, Sanjana Murali, Hans B. Liu, Daniela C. Salles, Brandon Lam, Pedram Argani, Tamara L. Lotan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The MiT/TFE transcription factors are phosphorylated and inactivated by mTORC1. Here, authors demonstrate that TFEB is paradoxically hypophosphorylated and activated in cells with TSC2 loss due to impaired lysosomal recruitment of the FLCN:FNIP2 comp
Externí odkaz:
https://doaj.org/article/4623887c9128432597fc0c714da4e302
Autor:
Klára Ščupáková, Oluwatobi T. Adelaja, Benjamin Balluff, Vinay Ayyappan, Caitlin M. Tressler, Nicole M. Jenkinson, Britt S.R. Claes, Andrew P. Bowman, Ashley M. Cimino-Mathews, Marissa J. White, Pedram Argani, Ron M.A. Heeren, Kristine Glunde
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
BACKGROUND. Although aberrant glycosylation is recognized as a hallmark of cancer, glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While preclinical studies show that the glycocalyx coating of cancer cells is involve
Externí odkaz:
https://doaj.org/article/1f2cb6eca1b24d099c90464c287adb91
Autor:
Sabra I. Djomehri, Maria E. Gonzalez, Felipe da Veiga Leprevost, Shilpa R. Tekula, Hui-Yin Chang, Marissa J. White, Ashley Cimino-Mathews, Boris Burman, Venkatesha Basrur, Pedram Argani, Alexey I. Nesvizhskii, Celina G. Kleer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and t
Externí odkaz:
https://doaj.org/article/22ef73a0f75440e0a22ac00ea2373d42
Autor:
Lina Ding, Ying Su, Anne Fassl, Kunihiko Hinohara, Xintao Qiu, Nicholas W. Harper, Sung Jin Huh, Noga Bloushtain-Qimron, Bojana Jovanović, Muhammad Ekram, Xiaoyuan Zi, William C. Hines, Maša Alečković, Carlos Gil del Alcazar, Ryan J. Caulfield, Dennis M. Bonal, Quang-De Nguyen, Vanessa F. Merino, Sibgat Choudhury, Gabrielle Ethington, Laura Panos, Michael Grant, William Herlihy, Alfred Au, Gedge D. Rosson, Pedram Argani, Andrea L. Richardson, Deborah Dillon, D. Craig Allred, Kirsten Babski, Elizabeth Min Hui Kim, Charles H. McDonnell, Jon Wagner, Ron Rowberry, Kristie Bobolis, Celina G. Kleer, E. Shelley Hwang, Joanne L. Blum, Simona Cristea, Piotr Sicinski, Rong Fan, Henry W. Long, Saraswati Sukumar, So Yeon Park, Judy E. Garber, Mina Bissell, Jun Yao, Kornelia Polyak
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Myoepithelial cells prevent tumour growth and invasion in DCIS. Here, the authors show that p63 and TCF7 cooperate to regulate a transcription factor network for the maintenance of normal myoepithelial function and altered expression of these genes p
Externí odkaz:
https://doaj.org/article/784cf49197cf4d50824d3974f6c39d75
Autor:
Anna Caliò, Matteo Brunelli, Stefano Gobbo, Pedram Argani, Enrico Munari, George Netto, Guido Martignoni
Publikováno v:
Cancers, Vol 13, Iss 10, p 2441 (2021)
Cathepsin K is a papain-like cysteine protease with high matrix-degrading activity. Among several cathepsins, cathepsin K is the most potent mammalian collagenase, mainly expressed by osteoclasts. This review summarizes most of the recent findings of
Externí odkaz:
https://doaj.org/article/3f3bd09a2f8747179c891fb98fc3fcc4
This unique book provides insight into the minds of experienced practicing pathologists and advice on how to better phrase frozen section diagnoses so as to avoid inappropriate surgical management. - Doody's ReviewsIntraoperative Frozen Sections pres
Autor:
Pedram Argani, Brendan C. Dickson, John M. Gross, Andres Matoso, Ezra Baraban, Cristina R. Antonescu
Publikováno v:
American Journal of Surgical Pathology. 47:709-716
Publikováno v:
Child's Nervous System. 39:1685-1689
Autor:
Pedram Argani, Sara E. Wobker, John M. Gross, Andres Matoso, Christopher D.M. Fletcher, Cristina R. Antonescu
Publikováno v:
The American journal of surgical pathology. 46(8)
Identical TFE3-related gene fusions may be found in renal cell carcinoma and mesenchymal neoplasms such as alveolar soft part sarcoma and TFE3-rearranged perivascular epithelioid cell tumor (PEComa). Among mesenchymal neoplasms, the ASPSCR1-TFE3 gene
Publikováno v:
International Journal of Surgical Pathology. 31:409-414
We report two novel cases of Xp11 translocation renal cell carcinomas with the MED15::TFE3 gene fusion in adult females aged 40 and 74 years. Both cases were extensively cystic and contained only minimal clear cells lining cysts and within septal wal