EFCAB4B (CRACR2A/Rab46) Genetic Variants Associated with COVID-19 Fatality.

Autor: Wang, Dapeng, Wiktor, Sabina D., Cheng, Chew W., Simmons, Katie J., Money, Ashley, Pedicini, Lucia, Carlton, Asya, Breeze, Alexander L., McKeown, Lynn

Publikováno v: COVID; Jul2024, Vol. 4 Issue 7, p1087-1099, 13p

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Rab46 integrates Ca²⁺ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies.

Autor: Miteva, Katarina T.¹ l.mckeown@leeds.ac.uk, Pedicini, Lucia¹, Wilson, Lesley A.¹, Jayasinghe, Izzy², Slip, Raphael G.¹, Marszalek, Katarzyna¹, Gaunt, Hannah J.¹, Bartoli, Fiona¹, Deivasigamani, Shruthi¹, Sobradillo, Diego¹, Beech, David J.¹, McKeown, Lynn¹

Publikováno v: Journal of Cell Biology. Jul2019, Vol. 218 Issue 7, p2232-2246. 15p.

Rab46: a novel player in mast cell function.

Autor: Pedicini L; Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, UK., Smith J; Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, UK., Savic S; Department of Clinical Immunology and Allergy, St James's University Hospital, Leeds, UK.; National Institute for Health Research-Leeds Biomedical Research Centre and Leeds Institute of Rheumatic and Musculoskeletal Medicine, Wellcome Trust Brenner Building, St James's University Hospital, Leeds, UK., McKeown L; Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, UK.

Publikováno v: Discovery immunology [Discov Immunol] 2023 Dec 22; Vol. 3 (1), pp. kyad028. Date of Electronic Publication: 2023 Dec 22 (Print Publication: 2024).