Zobrazeno 1 - 10
of 910
pro vyhledávání: '"Pediatric leukemia"'
Publikováno v:
Turkish Journal of Hematology, Vol 41, Iss 3, Pp 160-166 (2024)
Objective: The survival rates of children with acute lymphoblastic leukemia (ALL) have improved over the years, but infections remain a significant cause of morbidity and mortality. Chemotherapy has a range of harmful side effects including the loss
Externí odkaz:
https://doaj.org/article/43f1ca727d5a4fe9a0064f5e945bca98
Autor:
Meghan Collins, Ruggiero Gorgoglione, Valeria Impedovo, Xingxin Pan, Sathyaseelan Chakkarai, S. Stephen Yi, Alessia Lodi, Stefano Tiziani
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Background and aimsAberrations in the immunoglobulin heavy chain (IgH) locus are associated with poor prognosis in pediatric precursor B-cell acute lymphoblastic leukemia (BCP-ALL) patients. The primary objective of this pilot study is to enhance our
Externí odkaz:
https://doaj.org/article/3be38ee58bba47608984c83aa621a49e
Autor:
Julie M. Gastier-Foster, Fredrick Lutwama, Olive Mbabazi, Steven Mlenga, Kennedy Ulaya, Ruth Namazzi, E. Faith Hollingsworth, Dolores Lopez-Terrada, Kevin E. Fisher, Angshumoy Roy, Carl E. Allen, David G. Poplack, Rizine Mzikamanda, Nmazuo Ozuah, Peter Wasswa
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Risk stratification and molecular targeting have been key to increasing cure rates for pediatric cancers in high-income countries. In contrast, precise diagnosis in low-resource settings is hindered by insufficient pathology infrastructure. The Globa
Externí odkaz:
https://doaj.org/article/57f31e6043a84d179f230139c333fdd9
Autor:
Sandra Clara Soares, Louis J. D. Roux, Ana Rita Castro, Cristina Cardoso Silva, Rita Rodrigues, Viviana M. P. Macho, Fátima Silva, Céu Costa
Publikováno v:
Hematology Reports, Vol 15, Iss 3, Pp 491-502 (2023)
Acute lymphocytic leukemia (ALL) is the most frequent form of all childhood leukemias, mostly affecting children between 2 and 4 years old. Oral symptoms, such as mouth ulcers, mucositis, xerostomia, Herpes or Candidiasis, gingival enlargement and bl
Externí odkaz:
https://doaj.org/article/d3173328f89b4c17b0cd0124634ed964
Autor:
Irfan Al-Hussaini, Brandon White, Armon Varmeziar, Nidhi Mehra, Milagro Sanchez, Judy Lee, Nicholas P. DeGroote, Tamara P. Miller, Cassie S. Mitchell
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 6, p 1788 (2024)
Background: Datasets on rare diseases, like pediatric acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), have small sample sizes that hinder machine learning (ML). The objective was to develop an interpretable ML framework to elucid
Externí odkaz:
https://doaj.org/article/96c5e0ec11344db2828c716e0767b02f
Autor:
Yin Ting Cheung, Kenneth Kin-Wah To, Rong Hua, Chui Ping Lee, Agnes Sui-Ying Chan, Chi Kong Li
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundSurvivors of childhood acute lymphoblastic leukemia (ALL) are at-risk of developing cognitive impairment and neurobehavioral symptoms. Inflammation induced by a compromised health status during cancer survivorship is proposed as a pathophys
Externí odkaz:
https://doaj.org/article/8cdec53375444675bd0c2bff129b15da
Publikováno v:
Genes, Vol 14, Iss 10, p 1916 (2023)
The E26-transformation-specific (ETS) transcription factors regulate multiple aspects of the normal hematopoietic system. There is an increasing body of evidence suggesting aberrant ETS activity and its contribution to leukemia initiation and progres
Externí odkaz:
https://doaj.org/article/d503dd75777042ca92c327576ec3c092
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 521-525 (2022)
Abstract SRP54 mutations have recently been implicated in congenital neutropenia (CN) and the in‐frame deletion, p.Thr117del, is the most common pathogenic mutation reported. The largest study of SRP54‐mutated CN to‐date followed 23 patients fo
Externí odkaz:
https://doaj.org/article/43aa27e7f5854a5285d94d3d10701344
Autor:
Melike Sezgin Evim, Özlem Tüfekçi, Birol Baytan, Hale Ören, Solmaz Celebi, Beyza Ener, Kevser Üstün Elmas, Şebnem Yılmaz, Melek Erdem, Mustafa Kemal Hacımustafaoğlu, Adalet Meral Güneş
Publikováno v:
Turkish Journal of Hematology, Vol 39, Iss 2, Pp 94-102 (2022)
Objective: The incidence of invasive fungal infections (IFIs) has increased due to intensive chemotherapy in childhood leukemia. The aim of this study was to evaluate the incidence, risk factors, causative pathogens, and impact on survival of IFIs am
Externí odkaz:
https://doaj.org/article/5282372e0b9648c49d514bb84f636d65
Publikováno v:
Basic & Clinical Cancer Research, Vol 14, Iss 1 (2023)
Acute myeloid leukemia as one of the most common malignant disorders in adults is a heterogeneous clonal disorder of blood producing cells. The aim of this study was to analyze the expression of TNF-α, IL6, IL1-α, IL-10 and TGF-β1 gene in acute my
Externí odkaz:
https://doaj.org/article/cb7407dd27504b9397a7d0f3b1bea931