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Autor:
Michael J. Gonzalez, Gilberto Caraballo, Raúl H Morales-Borges, Ivette M Solís-Nolasco, Jose Olalde
Publikováno v:
Global Advances in Health and Medicine
Global Advances in Health and Medicine, Vol 9 (2020)
Global Advances in Health and Medicine, Vol 9 (2020)
Pediatric cases of a brainstem glioma are one of the most difficult tumors to treat. In children, this type of cancer is perhaps the most dreaded of cancers due to its poor prognosis, yet it remains an area of intense research. In the case presented
Autor:
Rajan Yadav
Publikováno v:
journal of Medical Science And clinical Research. 7
INTRODUCTION: Diffuse intrinsic pontine glioma (DIPG) is a highly morbid pediatric brainstem tumor. Tenascin-C (TNC) is an extracellular matrix protein associated with NOTCH pathway activation, and is expressed during normal brain development by olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bd8be025b8e810f5f4764008384f41
https://europepmc.org/articles/PMC5475012/
https://europepmc.org/articles/PMC5475012/
Publikováno v:
Journal of Neurosurgery: Pediatrics. 8:337-341
Object The early 20th century posed several challenges in the diagnosis and surgical treatment of intracranial tumors. However, this was a time in which more information was becoming more readily available based on pathological examination and surgic
Publikováno v:
PROTEOMICS – CLINICAL APPLICATIONS. 2:915-924
Little is known about the molecular characteristics of pediatric brainstem gliomas (BSG), which continue to have a dismal prognosis. Targeted molecular strategies are limited due to rarity of biopsy BSG specimen coupled with obstacles associated with
Autor:
Rintaro Hashizume, A. Plunti, Amanda Saratsis, Stewart Goldman, Rishi Lulla, Ali Shilatifard, Quanhong Ma, Jason Fangusaro, C. D. James, Craig Horbinski
Publikováno v:
Neuro-Oncology. 18:vi151-vi152
Autor:
Amanda Saratsis
Publikováno v:
Journal of Clinical Oncology. 33:10037-10037
10037 Background: Diffuse intrinsic pontine glioma (DIPG) is the most deadly solid tumor of childhood. Histone 3 mutation occurs in up to 80% of DIPGs, causing global epigenetic aberration. Tenasci...
Autor:
Subhash Gupta, Pramod Kumar Julka, Manikandan Annamalai, Supriya Mallick, Dayanand Sharma, Goura Kishor Rath, Haresh Kunhiparambath
Publikováno v:
Journal of Clinical Oncology. 33:e13045-e13045
e13045 Background: Introduction: Brainstem glioma (BSG) is an aggressive tumor of childhood. Treatment outcomes remain dismal and role of concurrent chemoradiotherapy (CTRT) is not established in t...
Autor:
Javad Nazarian, Amanda Saratsis
Publikováno v:
Cancer Research. 72:LB-416
Abstract: Diffuse intrinsic pontine glioma (DIPG) is a leading cause of brain tumor death in children due to lack of effective therapy. Genetic analysis of DIPG has been limited due to the lack of readily available tumor tissue for molecular study. M