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Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer

Autor: Lee, Soojung, Toft, Nicolai Juel, Axelsen, Trine Veje, Espejo, Maria Sofia, Pedersen, Tina Myhre, Mele, Marco, Pedersen, Helene Lintrup, Balling, Eva, Johansen, Tonje, Burton, Mark, Thomassen, Mads, Vahl, Pernille, Christiansen, Peer Michael, Boedtkjer, Ebbe

Publikováno v: Lee, S, Toft, N J, Axelsen, T V, Espejo, M S, Pedersen, T M, Mele, M, Pedersen, H L, Balling, E, Johansen, T, Burton, M, Thomassen, M, Vahl, P, Christiansen, P M & Boedtkjer, E 2023, ' Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer ', Breast Cancer Research, vol. 25, 46 . https://doi.org/10.1186/s13058-023-01644-1

Background Carbonic anhydrases catalyze CO2/HCO3– buffer reactions with implications for effective H+ mobility, pH dynamics, and cellular acid–base sensing. Yet, the integrated consequences of carbonic anhydrases for cancer and stromal cell funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbae1ffcaa764a161bf66160eeb6939
https://doi.org/10.1186/s13058-023-01644-1

Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility.

Autor: Homilius, Casper, Seefeldt, Jacob Marthinsen, Axelsen, Julie Sørensen, Pedersen, Tina Myhre, Sørensen, Trine Monberg, Nielsen, Roni, Wiggers, Henrik, Hansen, Jakob, Matchkov, Vladimir V., Bøtker, Hans Erik, Boedtkjer, Ebbe

Publikováno v: Basic Research in Cardiology; 9/9/2023, Vol. 118 Issue 1, p1-12, 12p

Overexpression of NOX2 Exacerbates AngII‐Mediated Cardiac Dysfunction and Metabolic Remodelling

Autor: Hansen, Synne, Pedersen, Tina Myhre, Marin, Julie, Boardman, Neoma Tove, Shah, Ajay M., Aasum, Ellen, Hafstad, Anne Dragøy

Publikováno v: Hansen, Pedersen, Marin, Boardman, Shah, Aasum, Hafstad. Overexpression of NOX2 Exacerbates AngII‐Mediated Cardiac Dysfunction and Metabolic Remodelling. Antioxidants. 2022;11(1)

Externí odkaz: https://hdl.handle.net/10037/25474

Augmented Ouabain-Induced Vascular Response Reduces Cardiac Efficiency in Mice with Migraine-Associated Mutation in the Na + , K + -ATPase α 2 -Isoform.

Autor: Rajanathan, Rajkumar, Pedersen, Tina Myhre, Guldbrandsen, Halvor Osterby, Olesen, Lenette Foldager, Thomsen, Morten B., Bøtker, Hans Erik, Matchkov, Vladimir V.

Publikováno v: Biomedicines; Feb2023, Vol. 11 Issue 2, p344, 19p