Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Peder Frederiksen"'
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Objectives Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation in multiple articular joints, causing pain, joint damage, and loss of joint function. Despite the successful development of disease-modifying
Externí odkaz:
https://doaj.org/article/d632f2e3b3814913af442492e9664f63
Autor:
Cecilie Liv Bager, Joseph P. M. Blair, Man-Hung Eric Tang, Joachim Høg Mortensen, Anne-Christine Bay-Jensen, Peder Frederiksen, Diana Leeming, Claus Christiansen, Morten Asser Karsdal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Citrullinated vimentin has been linked to several chronic and autoimmune diseases, but how citrullinated vimentin is associated with disease prevalence and genetic variants in a clinical setting remains unknown. The aim of this study was to
Externí odkaz:
https://doaj.org/article/c4f6f264d46947fc8cdd368070733f5f
Autor:
Anne Gitte Loft, Inge Juul Sørensen, Mikkel Østergaard, Susanne J Pedersen, Morten Asser Karsdal, Ole Rintek Madsen, Anne-C Bay-Jensen, Peder Frederiksen, Signe Holm Nielsen, Helena Port, Frederik Christiansen, Sengul Seven
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Objective To explore the potential of a panel of ECM remodelling markers as endotyping tools for axial spondyloarthritis (axSpA) by separating patients into subtypes and investigate how they differ among each other in disease activity scores and resp
Externí odkaz:
https://doaj.org/article/e93364d1901648c3841a9b940360238c
Autor:
Helena Port, Signe Holm Nielsen, Peder Frederiksen, Sofie Falkenløve Madsen, Anne-Christine Bay-Jensen, Inge Juul Sørensen, Bente Jensen, Anne Gitte Loft, Ole Rintek Madsen, Mikkel Østergaard, Susanne Juhl Pedersen
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Objective To investigate if extracellular matrix (ECM) blood-based biomarkers reflect the pharmacodynamic effect and response to TNF-α inhibitor therapy (adalimumab, ADA), in patients with axial spondyloarthritis (axSpA). Methods We investi
Externí odkaz:
https://doaj.org/article/b56739890238466ca4101e06eecc57b8
Autor:
Christian S. Thudium, Amalie Engstrøm, Anne-Christine Bay-Jensen, Peder Frederiksen, Nuria Jansen, Arjan De Zwart, Marike van der Leeden, Joost Dekker, Willem Lems, Leo Roorda, Willem Evert van Spil, Martin Van der Esch
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-8 (2023)
Abstract Objectives To investigate cartilage tissue turnover in response to a supervised 12-week exercise-related joint loading training program followed by a 6-month period of unsupervised training in patients with knee osteoarthritis (OA). To study
Externí odkaz:
https://doaj.org/article/b3db53bd49464766b5917216a4b81595
Autor:
Mette J. Nielsen, Grace E. Dolman, Rebecca Harris, Peder Frederiksen, Jane Chalmers, Jane I. Grove, William L. Irving, Morten A. Karsdal, Keyur Patel, Diana Julie Leeming, Indra Neil Guha
Publikováno v:
JHEP Reports, Vol 5, Iss 6, Pp 100743- (2023)
Background & Aims: Fibroblast activity is a key feature of fibrosis progression and organ function loss, leading to liver-related complications and mortality. The fibrogenesis marker, PRO-C3, has been shown to have prognostic significance in relation
Externí odkaz:
https://doaj.org/article/0e7fd31c9d4f4821b97670a60b11b3fe
Autor:
Federica Genovese, Peder Frederiksen, Anne-Christine Bay-Jensen, Morten A. Karsdal, Anna M. Milan, Birgitta Olsson, Mattias Rudebeck, James A. Gallagher, Lakshminarayan R. Ranganath
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10996 (2023)
Nitisinone has been approved for treatment of alkaptonuria (AKU). Non-invasive biomarkers of joint tissue remodelling could aid in understanding the molecular changes in AKU pathogenesis and how these can be affected by treatment. Serological and uri
Externí odkaz:
https://doaj.org/article/2ca18ea1b6a9427298bc1f350389b9c1
Autor:
Henrik Jessen, Nils Hoyer, Thomas S. Prior, Peder Frederiksen, Sarah R. Rønnow, Morten A. Karsdal, Diana J. Leeming, Elisabeth Bendstrup, Jannie M. B. Sand, Saher B. Shaker
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Remodeling of the extracellular matrix (ECM) is a central mechanism in the progression of idiopathic pulmonary fibrosis (IPF), and remodeling of type VI collagen has been suggested to be associated with disease progression. Biomar
Externí odkaz:
https://doaj.org/article/51e299aa98f7485bbe5ebc94f9457fa2
Autor:
Stefania Kalogera, Mylène P. Jansen, Anne-Christine Bay-Jensen, Peder Frederiksen, Morten A. Karsdal, Christian S. Thudium, Simon C. Mastbergen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9483 (2023)
The association between structural changes and pain sensation in osteoarthritis (OA) remains unclear. Joint deterioration in OA leads to the release of protein fragments that can either systemically (serum) or locally (synovial fluid; SF) be targeted
Externí odkaz:
https://doaj.org/article/b6ac27ae8fef49968302d21d6fcfcd49
Publikováno v:
Acta Orthopaedica, Vol 91, Iss 6, Pp 738-742 (2020)
Background and purpose — Total knee arthroplasty (TKA) has increased substantially in Sweden. We quantified the relative risk for TKA in the Swedish population for different BMI categories and age groups to investigate whether the continued increas
Externí odkaz:
https://doaj.org/article/cfecafd77a264a879bf7a86e7d16d5fc