Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Peder, Madsen"'
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://doaj.org/article/0dab2a5c70df4751af18ae27826dc208
Autor:
Camilla Gustafsen, Ditte Olsen, Joachim Vilstrup, Signe Lund, Anika Reinhardt, Niels Wellner, Torben Larsen, Christian B. F. Andersen, Kathrin Weyer, Jin-ping Li, Peter H. Seeberger, Søren Thirup, Peder Madsen, Simon Glerup
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
PCSK9 interacts with LDL receptor, causing its degradation, and consequently reduces the clearance of LDL. Here, Gustafsen et al. show that PCSK9 interacts with heparan sulfate proteoglycans and this binding favors LDLR degradation. Pharmacological i
Externí odkaz:
https://doaj.org/article/e6df4a8d335842ca8793c25354c164bc
Autor:
Simon Glerup, Maria Lume, Ditte Olsen, Jens R. Nyengaard, Christian B. Vaegter, Camilla Gustafsen, Erik I. Christensen, Mads Kjolby, Anders Hay-Schmidt, Dirk Bender, Peder Madsen, Mart Saarma, Anders Nykjaer, Claus M. Petersen
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 186-199 (2013)
Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that has reached clinical trials for Parkinson’s disease. GDNF binds to its coreceptor GFRα1 and signals through the transmembrane receptor tyrosine kinase RET, or
Externí odkaz:
https://doaj.org/article/57be80328bf040d6b8ff9eb14d9de451
Autor:
Carmela Matrone, Nicolas Dzamko, Peder Madsen, Mette Nyegaard, Regina Pohlmann, Rikke V Søndergaard, Louise B Lassen, Thomas L Andresen, Glenda M Halliday, Poul Henning Jensen, Morten S Nielsen
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160501 (2016)
Increasing evidence points to defects in autophagy as a common denominator in most neurodegenerative conditions. Progressive functional decline in the autophagy-lysosomal pathway (ALP) occurs with age, and the consequent impairment in protein process
Externí odkaz:
https://doaj.org/article/ed3cece4f69b467cbd97c22cb348adb6
Publikováno v:
Darki, A A, Madsen, S P & Dantan, A R 2022, ' Polarization-independent optical spatial differentiation with a doubly-resonant one-dimensional guided-mode grating ', Optics Express, vol. 30, no. 3, pp. 3962-3972 . https://doi.org/10.1364/OE.450981
We report on the design and experimental characterization of a suspended silicon nitride subwavelength grating possessing a polarization-independent guided-mode resonance at oblique incidence. At this resonant wavelength we observe that the transvers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7a39a648650f93ab1cb49bda268669
https://pure.au.dk/portal/da/publications/polarizationindependent-optical-spatial-differentiation-with-a-doublyresonant-onedimensional-guidedmode-grating(c7df6910-6619-4f36-b2c3-1745b64b5592).html
https://pure.au.dk/portal/da/publications/polarizationindependent-optical-spatial-differentiation-with-a-doublyresonant-onedimensional-guidedmode-grating(c7df6910-6619-4f36-b2c3-1745b64b5592).html
Autor:
Mads Kjolby, Peter Breining, Karen Pedersen, Niels Wellner, Karen Sørensen, Anette Gjessing, Dovile Januliene, Dorthe Vittrup, Arulmani Manavalan, Maarten Rotman, Gangadaar Thotakura, Guido Hermey, Peder Madsen, Christian Vaegter, Søren Thirup, Olof Asplund, Rashmi Prasad, Edwin Parlevliet, Patrick Rensen, Andreas Madsen, Birgitte Holst, Olav Andersen, Arne Moller, Torben Hansen, Anders Nykjaer
Type 2 diabetes has reached endemic proportions and is a substantial burden for the affected patients and the society. Along with lifestyle factors, a number of genetic loci predisposing to type 2 diabetes have been identified, including SORCS1 that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec672209d92bb95a06749b31dbc88c6e
https://doi.org/10.21203/rs.3.rs-1299440/v1
https://doi.org/10.21203/rs.3.rs-1299440/v1
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Pärn, A, Olsen, D, Tuvikene, J, Kaas, M, Borisova, E, Bilgin, M, Elhauge, M, Vilstrup, J, Madsen, P, Ambrozkiewicz, M C, Goz, R U, Timmusk, T, Tarabykin, V, Gustafsen, C & Glerup, S 2022, ' PCSK9 deficiency alters brain lipid composition without affecting brain development and function ', Frontiers in Molecular Neuroscience, vol. 15, pp. 1084633 . https://doi.org/10.3389/fnmol.2022.1084633
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3581b02e08f0a7fb6ef1652b1549c718
https://pure.au.dk/portal/da/publications/pcsk9-deficiency-alters-brain-lipid-composition-without-affecting-brain-development-and-function(0bf5ac93-a0f7-4784-a89e-304623a8fe54).html
https://pure.au.dk/portal/da/publications/pcsk9-deficiency-alters-brain-lipid-composition-without-affecting-brain-development-and-function(0bf5ac93-a0f7-4784-a89e-304623a8fe54).html
Autor:
Rashmi B. Prasad, Torben Hansen, Patrick C.N. Rensen, Sune Skeldal, Dorthe Maria Vittrup, Karen M. Pedersen, Olof Asplund, Christian Bjerggaard Vaegter, Anette Marianne Prior Gjessing, Andreas N. Madsen, Karen Marie Juul Sørensen, Mads Kjolby, Maarten Rotman, Dovile Januliene, Olav M. Andersen, Guido Hermey, Edwin T. Parlevliet, Birgitte Holst, Arne Moller, Gangadaar Thotakura, Ernst-Martin Füchtbauer, Søren Thirup, Peder Madsen, Niels Wellner, Peter Breining, Arulmani Manavalan
Type II diabetes mellitus (T2DM) has reached endemic levels and comprises a substantial burden to the patient and the society. Along with lifestyle factors, a number of genetic loci predisposing to T2DM have been suggested including SORCS1 that encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbdadf328d061149c37f06c00ea13f49
https://doi.org/10.1101/2020.11.10.376178
https://doi.org/10.1101/2020.11.10.376178
Autor:
Julio E. Celis, Peder Madsen
Publikováno v:
Growth Regulation and Carcinogenesis ISBN: 9781351072311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86756b392b4c70f35fdf64a6f6f4d704
https://doi.org/10.1201/9781351072311-1
https://doi.org/10.1201/9781351072311-1
Publikováno v:
Growth Regulation and Carcinogenesis ISBN: 9781351072311
Growth Regulation and Carcinogenesis
Growth Regulation and Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31342e6ee4bf07e70ece34902c4e60ff
https://doi.org/10.1201/9781351072311-2
https://doi.org/10.1201/9781351072311-2