Systemic inflammation and lymphocyte activation precede rheumatoid arthritis.

Autor: He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Rachid Zaim S, Bennett CE, Ravisankar P, Dornisch EM, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen K, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.

Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα ⁺ T cell subset and broad age-related molecular reprogramming across the T cell compartment.

Autor: Thomson Z; Allen Institute for Immunology, Seattle, WA, USA., He Z; Allen Institute for Immunology, Seattle, WA, USA., Swanson E; Allen Institute for Immunology, Seattle, WA, USA.; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA., Henderson K; Allen Institute for Immunology, Seattle, WA, USA., Phalen C; Allen Institute for Immunology, Seattle, WA, USA., Zaim SR; Allen Institute for Immunology, Seattle, WA, USA., Pebworth MP; Allen Institute for Immunology, Seattle, WA, USA., Okada LY; Allen Institute for Immunology, Seattle, WA, USA., Heubeck AT; Allen Institute for Immunology, Seattle, WA, USA., Roll CR; Allen Institute for Immunology, Seattle, WA, USA.; Microbiology, Immunology and Cancer Biology (MICaB) Program, University of Minnesota, Minneapolis, Minneapolis, MN, USA., Hernandez V; Allen Institute for Immunology, Seattle, WA, USA., Weiss M; Allen Institute for Immunology, Seattle, WA, USA., Genge PC; Allen Institute for Immunology, Seattle, WA, USA., Reading J; Allen Institute for Immunology, Seattle, WA, USA., Giles JR; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Manne S; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Dougherty J; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Jasen CJ; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Greenplate AR; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.; Immune Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Becker LA; Allen Institute for Immunology, Seattle, WA, USA., Graybuck LT; Allen Institute for Immunology, Seattle, WA, USA., Vasaikar SV; Allen Institute for Immunology, Seattle, WA, USA.; Seagen, Bothell, WA, USA., Szeto GL; Allen Institute for Immunology, Seattle, WA, USA.; Seagen, Bothell, WA, USA., Savage AK; Allen Institute for Immunology, Seattle, WA, USA., Speake C; Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA., Buckner JH; Center for Translational Immunology, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA., Li XJ; Allen Institute for Immunology, Seattle, WA, USA., Bumol TF; Allen Institute for Immunology, Seattle, WA, USA., Wherry EJ; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Torgerson TR; Allen Institute for Immunology, Seattle, WA, USA., Vella LA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Henrickson SE; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Pediatrics, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Skene PJ; Allen Institute for Immunology, Seattle, WA, USA. peter.skene@alleninstitute.org., Gustafson CE; Allen Institute for Immunology, Seattle, WA, USA. claire.gustafson@alleninstitute.org.

Publikováno v: Nature immunology [Nat Immunol] 2024 Mar; Vol. 25 (3), pp. 577.

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence.

Autor: Talla A, Vasaikar SV, Lemos MP, Moodie Z, Lee Pebworth MP, Henderson KE, Cohen KW, Czartoski JL, Lai L, Suthar MS, Heubeck AT, Genge PC, Roll CR, Weiss M, Reading J, Kondza N, MacMillan H, Fong OC, Thomson ZJ, Graybuck LT, Okada LY, Newell EW, Coffey EM, Meijer P, Becker LA, De Rosa SC, Skene PJ, Torgerson TR, Li XJ, Szeto GL, McElrath MJ, Bumol TF

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2021 Aug 19. Date of Electronic Publication: 2021 Aug 19.

Cell-type-specific 3D epigenomes in the developing human cortex.

Autor: Song M; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California, San Francisco, San Francisco, CA, USA., Pebworth MP; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA.; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA., Yang X; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Abnousi A; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Fan C; Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Wen J; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Rosen JD; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA., Choudhary MNK; Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA., Cui X; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Jones IR; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Bergenholtz S; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Eze UC; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA.; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA., Juric I; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Li B; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Maliskova L; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Lee J; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA., Liu W; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA., Pollen AA; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA.; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Li Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA.; Department of Computer Science, University of North Carolina, Chapel Hill, NC, USA., Wang T; Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO, USA.; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA., Hu M; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. hum@ccf.org., Kriegstein AR; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA. arnold.kriegstein@ucsf.edu.; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA. arnold.kriegstein@ucsf.edu., Shen Y; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA. yin.shen@ucsf.edu.; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA. yin.shen@ucsf.edu.; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. yin.shen@ucsf.edu.

Publikováno v: Nature [Nature] 2020 Nov; Vol. 587 (7835), pp. 644-649. Date of Electronic Publication: 2020 Oct 14.

A novel 2.5D culture platform to investigate the role of stiffness gradients on adhesion-independent cell migration.

Autor: Pebworth MP; Department of Bioengineering, Santa Clara University, Santa Clara, California, United States of America., Cismas SA; Department of Bioengineering, Santa Clara University, Santa Clara, California, United States of America., Asuri P; Department of Bioengineering, Santa Clara University, Santa Clara, California, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Oct 13; Vol. 9 (10), pp. e110453. Date of Electronic Publication: 2014 Oct 13 (Print Publication: 2014).