Zobrazeno 1 - 10
of 375
pro vyhledávání: '"Pearse A. Keane"'
Autor:
Josie Carmichael, Enrico Costanza, Ann Blandford, Robbert Struyven, Pearse A. Keane, Konstantinos Balaskas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Artificial intelligence (AI) has great potential in ophthalmology. We investigated how ambiguous outputs from an AI diagnostic support system (AI-DSS) affected diagnostic responses from optometrists when assessing cases of suspected retinal
Externí odkaz:
https://doaj.org/article/9a02226b47b94b5fa777ff737cfc7960
Autor:
Alexander P. L. Martindale, Benjamin Ng, Victoria Ngai, Aditya U. Kale, Lavinia Ferrante di Ruffano, Robert M. Golub, Gary S. Collins, David Moher, Melissa D. McCradden, Lauren Oakden-Rayner, Samantha Cruz Rivera, Melanie Calvert, Christopher J. Kelly, Cecilia S. Lee, Christopher Yau, An-Wen Chan, Pearse A. Keane, Andrew L. Beam, Alastair K. Denniston, Xiaoxuan Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The Consolidated Standards of Reporting Trials extension for Artificial Intelligence interventions (CONSORT-AI) was published in September 2020. Since its publication, several randomised controlled trials (RCTs) of AI interventions have been
Externí odkaz:
https://doaj.org/article/a2d27b1908784851a58e618b7b71f7b0
Autor:
Danli Shi, MD, PhD, Yukun Zhou, ME, Shuang He, MD, Siegfried K. Wagner, MD, PhD, Yu Huang, MD, PhD, Pearse A. Keane, MD, PhD, Daniel S.W. Ting, MD, PhD, Lei Zhang, PhD, Yingfeng Zheng, PhD, Mingguang He, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 3, Pp 100441- (2024)
Purpose: We aim to use fundus fluorescein angiography (FFA) to label the capillaries on color fundus (CF) photographs and train a deep learning model to quantify retinal capillaries noninvasively from CF and apply it to cardiovascular disease (CVD) r
Externí odkaz:
https://doaj.org/article/6800ce92746641c7b1796f949dd6d0fb
Autor:
Dun Jack Fu, Veronika Lipkova, Bart Liefers, Sophie Glinton, Livia Faes, Alex McKeown, Lukas Scheibler, Nikolas Pontikos, Praveen J. Patel, Gongyu Zhang, Pearse A. Keane, Konstantinos Balaskas
Publikováno v:
Ophthalmology and Therapy, Vol 12, Iss 6, Pp 3143-3158 (2023)
Abstract Introduction To evaluate the effect pegcetacoplan, a C3 and C3b inhibitor, on the rate of progression of geographic atrophy (GA) as assessed by spectral domain optical coherence tomography (SD-OCT) using a split-person study design and deep-
Externí odkaz:
https://doaj.org/article/f5f43e69d85a499a9b021ce09e606f78
Autor:
Camilo Brandao-de-Resende, Mariane Melo, Elsa Lee, Anish Jindal, Yan N. Neo, Priyanka Sanghi, Joao R. Freitas, Paulo V.I.P. Castro, Victor O.M. Rosa, Guilherme F.S. Valentim, Maria Luisa O. Higino, Gordon R. Hay, Pearse A. Keane, Daniel V. Vasconcelos-Santos, Alexander C. Day
Publikováno v:
EClinicalMedicine, Vol 66, Iss , Pp 102331- (2023)
Summary: Background: A substantial proportion of attendances to ophthalmic emergency departments are for non-urgent presentations. We developed and evaluated a machine learning system (DemDx Ophthalmology Triage System: DOTS) to optimise triage, with
Externí odkaz:
https://doaj.org/article/b9ef9b0379d9428f92640e6b4c9074cb
Autor:
Ting Fang Tan, MBBS, Arun James Thirunavukarasu, BA MB, BChir (Cantab), J. Peter Campbell, MD, MPH, Pearse A. Keane, MD, FRCOphth, Louis R. Pasquale, MD, FARVO, Michael D. Abramoff, MD, PhD, Jayashree Kalpathy-Cramer, PhD, Flora Lum, MD, Judy E. Kim, MD, FARVO, Sally L. Baxter, MD, MSc, Daniel Shu Wei Ting, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100394- (2023)
The rapid progress of large language models (LLMs) driving generative artificial intelligence applications heralds the potential of opportunities in health care. We conducted a review up to April 2023 on Google Scholar, Embase, MEDLINE, and Scopus us
Externí odkaz:
https://doaj.org/article/b1a869c7ddda477ea610000e433132d7
Autor:
Aditya U. Kale, MBBS, Andrew Mills, Emily Guggenheim, PhD, David Gee, Samuel Bodza, MS, Aparna Anumakonda, Rima Doal, MSc, Rowena Williams, MSc, Suzy Gallier, BSc, Wen Hwa Lee, PhD, Paul Galsworthy, BA, Manjit Benning, BSc (Hons), FCMI, Hilary Fanning, Pearse A. Keane, MD, FRCOphth, Alastair K. Denniston, PhD, Susan P. Mollan, FRCOphth
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100293- (2023)
Purpose: Diabetic retinopathy (DR) is the most common microvascular complication associated with diabetes mellitus (DM), affecting approximately 40% of this patient population. Early detection of DR is vital to ensure monitoring of disease progressio
Externí odkaz:
https://doaj.org/article/ad02ef09d548460fa13e732b94bb37c5
Autor:
Sezgi Kaçar, Danko Coric, Giovanni Ometto, Giovanni Montesano, Alastair K. Denniston, Pearse A. Keane, Bernard M. J. Uitdehaag, David P. Crabb, Menno M. Schoonheim, Axel Petzold, Eva M. M. Strijbis
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 36 (2023)
Background: The glymphatic system removes neurodegenerative debris. The ocular glymphatic outflow is from the eye to the proximal optic nerve. In multiple sclerosis (MS), atrophy of the optic nerve increases the glymphatic outflow space. Here, we tes
Externí odkaz:
https://doaj.org/article/709d0031c41c410a95b2c622875e7d3c
Autor:
Yoga Advaith Veturi, MSc, William Woof, PhD, Teddy Lazebnik, PhD, Ismail Moghul, PhD, Peter Woodward-Court, PhD, MBBS, Siegfried K. Wagner, BMBCh, Thales Antonio Cabral de Guimarães, PhD, MD, Malena Daich Varela, PhD, MD, Bart Liefers, PhD, Praveen J. Patel, MBBChir MD(Res), Stephan Beck, PhD, Andrew R. Webster, FRCOphth, Omar Mahroo, PhD, MBBChir, Pearse A. Keane, MD, MB BCH BAO, Michel Michaelides, MD, Konstantinos Balaskas, MD, Nikolas Pontikos, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 2, Pp 100258- (2023)
Purpose: Rare disease diagnosis is challenging in medical image-based artificial intelligence due to a natural class imbalance in datasets, leading to biased prediction models. Inherited retinal diseases (IRDs) are a research domain that particularly
Externí odkaz:
https://doaj.org/article/12ee7796b3234e6eaea51052d9cf4f74
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 28, Iss , Pp 101709- (2022)
Purpose: To describe a novel optical coherence tomography (OCT) finding at the vitreomacular interface (VMI), and report its association with advanced choroidal neovascularisation (CNV). Observations: Optical coherence tomography (OCT) scans performe
Externí odkaz:
https://doaj.org/article/3cf1b4cc24bd40f5902e34a20b724042