Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pearl Huang"'
Autor:
Kai‐Chih Huang, Shan Lou, Chih‐Chieh Wang, Monica S. Thanawala, Jesse Turner, Alex Fink, Lexiang Ji, Masoud Sadaghiani, Pearl Huang, Hongyue Dai
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 3, Pp 170-179 (2022)
Abstract The nervous system plays an important role in human health and disease, and the unique morphologies of the neurons underlie its ability to interface with tissues and organs throughout the entire body. In vitro, neurons can be grown alone or
Externí odkaz:
https://doaj.org/article/126c128fb7ea4ae29d3de54d8a7a10cb
Autor:
Hongyue Dai, Shan Lou, Yanbo Zhang, Monica Thanawala, Kai‐Chih Huang, Lexiang Ji, Sarah Carden, Tiffany Liao, Mandana Abbassi, Chengyi J. Shu, Alexandra Lantermann, Masoud Sadaghiani, Daniel Blom, John Wagner, Pearl Huang
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 1, Pp 76-89 (2022)
Abstract Tumor innervation has recently been documented and characterized in various settings and tumor types. However, the role that nerves innervating tumors play in the pathogenesis of cancer has not been clarified. In this study, we searched for
Externí odkaz:
https://doaj.org/article/0e0fcf6304ed4f279d36259b70fff502
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 10, Pp 802-813 (2021)
Abstract A hallmark of endometriosis – a chronic debilitating condition whose causes are poorly understood – is neuronal innervation of lesions. Recent evidence demonstrates that the peripheral nervous system plays an important role in the pathop
Externí odkaz:
https://doaj.org/article/c3d957bdd68545c784c721bfe8f069dc
Autor:
Kai-Chih Huang, Alison Miller, Lexiang Ji, Monica Thanawala, John R. Wagner, Pearl Huang, Hongyue Dai
Publikováno v:
Journal of Pathology Informatics, Vol 13, Iss , Pp 100054- (2022)
Externí odkaz:
https://doaj.org/article/482a4aaf7d8746d7b093f2a77000b0b0
Autor:
Kai-Chih Huang, Alison Miller, Daniel Krasnonosenkikh, Monica Thanawala, George V. Thomas, Alexandra Lantermann, Masoud Sadaghiani, Hongyue Dai, John R. Wagner, Pearl Huang
Publikováno v:
Journal of Pathology Informatics, Vol 13, Iss , Pp 100053- (2022)
Externí odkaz:
https://doaj.org/article/e2187ba62c104857ba8ed277493a269c
683 A novel mechanism of neuropilin-1 inhibition results in improved tumor growth inhibition in vivo
Autor:
Eric Zhu, Daniel Blom, Shalini Sethumadhavan, Chengfeng Merriman, Katherine Molloy, Alexandria Fink, Shan Lou, Andrew Rogantino, Ameya Apte, Mandana abbassi, Tiffany Liao, Hongyue Dai, Aaron Fulgham, Jonathan Hurov, Pearl Huang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/eb8c2e1b1f54498abc86b8a7c8000d7d
Autor:
Johann S. de Bono, Li Yan, Timothy A. Yap, Brianne Kaiser, Victor Moreno, Kyriakos P. Papadopoulos, Ying-Ming Jou, Ernestina Tetteh, Anne Morosky, Keith A. Shannon, Maria Learoyd, Pearl Huang, Paul D. Smith, Eric H. Rubin, Jeffrey M. Skolnik, Christopher R. Garrett, David Olmos, Richard D. Baird, Amita Patnaik, David R. Gandara, Vassiliki Papadimitrakopoulou, Udai Banerji, Michael Ong, Khurum Khan, Anthony W. Tolcher
Supplementary Tables S1-S4 and Figures S1-S3. Tables S1/S2: % tumor response in mice with HCT116 and A2058 tumor xenografts following treatment; Table S3: Diagram showing dose-decision guidelines utilized in the MK-2206 clinical study based on observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f597346417fd8a518a7f25a4fa93a7d
https://doi.org/10.1158/1078-0432.22458612
https://doi.org/10.1158/1078-0432.22458612
Autor:
David A. Tuveson, Youngkyu Park, Duncan I. Jodrell, Kenneth H. Yu, Paul Smith, Pearl Huang, Tashinga E. Bapiro, Kevin Wright, Dea Filippini, Lindsey A. Baker, Iok In Christine Chio, Daniel Öhlund, Chang-Il Hwang, Tobiloba E. Oni, Kristopher K. Frese, Dannielle D. Engle, Hervé Tiriac, Vincenzo Corbo, Mariano Ponz-Sarvise
Purpose:KRAS is mutated in the majority of pancreatic ductal adenocarcinoma. MAPK and PI3K-AKT are primary KRAS effector pathways, but combined MAPK and PI3K inhibition has not been demonstrated to be clinically effective to date. We explore the resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3e93ddb67be2d51b95b7b517279251
https://doi.org/10.1158/1078-0432.c.6528179.v1
https://doi.org/10.1158/1078-0432.c.6528179.v1
Autor:
Johann S. de Bono, Li Yan, Timothy A. Yap, Brianne Kaiser, Victor Moreno, Kyriakos P. Papadopoulos, Ying-Ming Jou, Ernestina Tetteh, Anne Morosky, Keith A. Shannon, Maria Learoyd, Pearl Huang, Paul D. Smith, Eric H. Rubin, Jeffrey M. Skolnik, Christopher R. Garrett, David Olmos, Richard D. Baird, Amita Patnaik, David R. Gandara, Vassiliki Papadimitrakopoulou, Udai Banerji, Michael Ong, Khurum Khan, Anthony W. Tolcher
Purpose: KRAS is the most commonly mutated oncogene in human tumors. KRAS-mutant cells may exhibit resistance to the allosteric MEK1/2 inhibitor selumetinib (AZD6244; ARRY-142886) and allosteric AKT inhibitors (such as MK-2206), the combination of wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7c62bba7d8cb8fd656692135284d90
https://doi.org/10.1158/1078-0432.c.6524007
https://doi.org/10.1158/1078-0432.c.6524007
Autor:
David A. Tuveson, Youngkyu Park, Duncan I. Jodrell, Kenneth H. Yu, Paul Smith, Pearl Huang, Tashinga E. Bapiro, Kevin Wright, Dea Filippini, Lindsey A. Baker, Iok In Christine Chio, Daniel Öhlund, Chang-Il Hwang, Tobiloba E. Oni, Kristopher K. Frese, Dannielle D. Engle, Hervé Tiriac, Vincenzo Corbo, Mariano Ponz-Sarvise
Supplementary Figures 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4d51b5fe19cd2bac155356020f3487
https://doi.org/10.1158/1078-0432.22472273
https://doi.org/10.1158/1078-0432.22472273