Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Pearl A. Sutter"'
Autor:
Melissa R. Pergande, Christina Kang, Diann George, Pearl A. Sutter, Stephen J. Crocker, Stephanie M. Cologna, Maria I. Givogri
Publikováno v:
Lipids in Health and Disease, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Recent findings show that extracellular vesicle constituents can exert short- and long-range biological effects on neighboring cells in the brain, opening an exciting avenue for investigation in the field of neurodegenerative dise
Externí odkaz:
https://doaj.org/article/81ba21c6879f47b39112097282b4e604
Autor:
Megan E. Rouillard, Jingwen Hu, Pearl A. Sutter, Hee Won Kim, Jeffrey K. Huang, Stephen J. Crocker
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
HMGB1 is a highly conserved, ubiquitous protein in eukaryotic cells. HMGB1 is normally localized to the nucleus, where it acts as a chromatin associated non-histone binding protein. In contrast, extracellular HMGB1 is an alarmin released by stressed
Externí odkaz:
https://doaj.org/article/a4963e36f09b4cdaba664da72e4c6273
Autor:
Sophia J. Angelo, Megan G. Anderson, Pearl A. Sutter, Patrick J. Halloran, Katherine R. Kavanagh, Mitch R. Paro, Jonathan E. Martin, Markus J. Bookland, Ian C. Michelow, David S. Hersh
Publikováno v:
Journal of Neurosurgery: Pediatrics. :1-11
OBJECTIVE Focal intracranial infections (epidural abscesses, subdural empyemas, and intraparenchymal abscesses) are uncommon complications of sinusitis and otitis media but can be associated with significant morbidity. Treatment typically requires ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca336beadfab4f9abe9c8c58aaaaf7de
https://doi.org/10.3171/2023.4.peds23130
https://doi.org/10.3171/2023.4.peds23130
Autor:
Pearl A. Sutter, Cory M. Willis, Antoine Menoret, Alexandra M. Nicaise, Anthony Sacino, Arend. H. Sikkema, Evan Jellison, Kyaw K. Win, David K. Han, William Church, Wia Baron, Anthony T. Vella, Stephen J. Crocker
Publikováno v:
bioRxiv
Astrocyte activation is associated with neuropathology and the production of tissue inhibitor of metalloproteinase-1 (TIMP1). TIMP1 is a pleiotropic extracellular protein that functions both as a protease inhibitor and as a growth factor. We have pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16abc3721668b894d532a6440c9706f
https://europepmc.org/articles/PMC9949145/
https://europepmc.org/articles/PMC9949145/
Publikováno v:
Aging and Disease
Astrocytes are an abundant and dynamic glial cell exclusive to the central nervous system (CNS). In the context of injury, inflammation, and/or diseases of the nervous system, astrocyte responses, termed reactive astrogliosis, are a recognized pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2700ec0b1733d068105395a88db89f1
http://europepmc.org/articles/PMC8407882
http://europepmc.org/articles/PMC8407882
Autor:
Pearl A. Sutter, Antoine Ménoret, Evan R. Jellison, Alexandra M. Nicaise, Allison M. Bradbury, Anthony T. Vella, Ernesto R. Bongarzone, Stephen J. Crocker
Globoid cell leukodystrophy (GLD) or Krabbe’s disease is a fatal genetic demyelinating disease of the central nervous system caused by loss-of-function mutations in the galactosylceramidase (galc) gene. While the metabolic basis for disease is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd9096fc83bfcb0bed7040b587115203
https://doi.org/10.1101/2022.09.30.510367
https://doi.org/10.1101/2022.09.30.510367
Autor:
Pearl A. Sutter, Stephen J. Crocker
Publikováno v:
Curr Opin Neurobiol
The contribution of the cells within the central nervous system (CNS) toward adaptive immune responses is emerging and incompletely understood. Recent findings indicate important functional interactions between T-cells and glial cells within the CNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5736d4e5ce31c5123af0bef5d84f70d0
https://pubmed.ncbi.nlm.nih.gov/36371828
https://pubmed.ncbi.nlm.nih.gov/36371828
Publikováno v:
Neurochemical Research. 45:694-707
The aging brain is associated with significant pathophysiological changes reflected in changes in astrocyte function. In this study, we hypothesized that the response of astrocytes to mechanical and inflammatory stimulation would differ with long-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5575424a79696772f2f8d2bd8a2e9e9c
https://doi.org/10.1007/s11064-019-02937-8
https://doi.org/10.1007/s11064-019-02937-8
Autor:
Megan E. Rouillard, Jingwen Hu, Pearl A. Sutter, Hee Won Kim, Jeffrey K. Huang, Stephen J. Crocker
Publikováno v:
Frontiers in cellular neuroscience. 16
HMGB1 is a highly conserved, ubiquitous protein in eukaryotic cells. HMGB1 is normally localized to the nucleus, where it acts as a chromatin associated non-histone binding protein. In contrast, extracellular HMGB1 is an alarmin released by stressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3ce6651184f6b9518d36a3b9906d13
https://pubmed.ncbi.nlm.nih.gov/35573828
https://pubmed.ncbi.nlm.nih.gov/35573828
Publikováno v:
Current opinion in pharmacology. 63
Recent studies have implicated cellular senescence as a disease-related process linked to progressive forms of multiple sclerosis (MS). Herein, we present an overview of the current pharmacopeia of cellular senescence affecting compounds and evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c4a379451158221ea67984d59ffe22
https://pubmed.ncbi.nlm.nih.gov/35189476
https://pubmed.ncbi.nlm.nih.gov/35189476