Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Pearl A Campbell"'
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e553 (2007)
Stem cells are characterized by two defining features, the ability to self-renew and to differentiate into highly specialized cell types. The POU homeodomain transcription factor Oct4 (Pou5f1) is an essential mediator of the embryonic stem cell state
Externí odkaz:
https://doaj.org/article/020868549367415fbadaa1a090e5864e
Autor:
Srishti Kumar, Alexandria Bennett, Pearl A. Campbell, Gareth Palidwor, Bryan Lo, Theodore J. Perkins, Surapon Nochaiwong, Harmanjatinder S. Sekhon, David J. Stewart, Kednapa Thavorn
Publikováno v:
Current Oncology, Vol 29, Iss 8, Pp 5238-5246 (2022)
Background: Next-generation sequencing (NGS) of tumor genomes has changed and improved cancer treatment over the past few decades. It can inform clinicians on the optimal therapeutic approach in many of the solid and hematologic cancers, including no
Externí odkaz:
https://doaj.org/article/4ac0df78c6404e88bff561f0547ad977
Autor:
Kevin D. Burns, Joseph Zimpelmann, Karishma Tailor, Jose L. Viñas, Matthew Spence, Alex Gutsol, Pearl A. Campbell, Christopher J. Porter, Adrianna Douvris
Publikováno v:
Clinical Science. 134:1887-1909
Female sex protects against development of acute kidney injury (AKI). While sex hormones may be involved in protection, the role of differential gene expression is unknown. We conducted gene profiling in male and female mice with or without kidney is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c699706c57d225c641bfe4ee39d626
https://doi.org/10.1042/cs20200168
https://doi.org/10.1042/cs20200168
Autor:
Alex Gutsol, Adrianna Douvris, Kevin D. Burns, Jose L. Viñas, Matthew Spence, Joseph Zimpelmann, Pearl A. Campbell, Christopher J. Porter
Publikováno v:
Kidney international. 100(3)
Acute kidney injury (AKI) carries high morbidity and mortality, and effective treatments are lacking. Preclinical models support involvement of micro-RNAs (miRs) in AKI pathogenesis, although effects on the kidney transcriptome are unclear. We previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6474a598c024931a07964f442dc55d
https://pubmed.ncbi.nlm.nih.gov/34181969
https://pubmed.ncbi.nlm.nih.gov/34181969
Autor:
Bryan Lo, Ali Karimnezhad, Kednapa Thavorn, Pearl A. Campbell, David J. Stewart, Gareth A. Palidwor, Theodore J. Perkins
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-14 (2020)
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-14 (2020)
Background Treating cancer depends in part on identifying the mutations driving each patient’s disease. Many clinical laboratories are adopting high-throughput sequencing for assaying patients’ tumours, applying targeted panels to formalin-fixed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94666b5b2a5eb07fbbeed8fa60b4161e
https://doi.org/10.1101/2019.12.31.891952
https://doi.org/10.1101/2019.12.31.891952
Autor:
Jose L. Viñas, Dylan Burger, Anthony Carter, David S. Allan, Pearl A. Campbell, Alex Gutsol, William Knoll, Joseph Zimpelmann, Kevin D. Burns, Randa Haneef
Publikováno v:
Kidney International. 90(6):1238-1250
Administration of human cord blood endothelial colony-forming cells (ECFCs) or their exosomes protects mice against kidney ischemia/reperfusion injury. Here we studied the microRNA (miRNA) content of ECFC exosomes and the role of miRNA transfer in ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c4dbd21b956155abbbac65ab93a7b0
Autor:
Pearl A. Campbell, David J. Stewart, Harmanjatinder S. Sekhon, Bryan Lo, Kednapa Thavorn, Theodore J. Perkins, Suzanne Kamel-Reid, Robin Urquhart, Ali Karimnezhad
Publikováno v:
Cancer Research. 79:3355-3355
Next generation sequencing (NGS) has been used to catalogue genetic mutations in cancer. Recent studies employing NGS have identified specific genetic mutations that reliably predict therapeutic success with targeted treatment in many forms of cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e24ad1e245af40d4f033c4e50077019
https://doi.org/10.1158/1538-7445.am2019-3355
https://doi.org/10.1158/1538-7445.am2019-3355
Autor:
P. G. Rolf, Pearl A. Campbell, Marc Bourbeau, van Heeswijk, Isabelle Seguin, Bobby M. Chauhan, D. William Cameron, Brian C. Foster
Publikováno v:
The Journal of Clinical Pharmacology. 46:758-767
This study investigated the effect of single-dose and steady-state lopinavir/ritonavir on the exposure to fexofenadine, as a measure of P-glycoprotein activity. Sixteen volunteers (8 women) received single-dose oral fexofenadine 120 mg alone, in comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe67b56665662cbca5677224b0c6b7d9
https://doi.org/10.1177/0091270006288733
https://doi.org/10.1177/0091270006288733
Autor:
Paul M. Krzyzanowski, Matthew R. Huska, Carolina Perez-Iratxeta, Evan Hughes, Pearl A. Campbell, Christopher J. Porter, Gareth A. Palidwor, Enrique M. Muro, Neal A. Sanche, Brian P Suomela, Michael A. Rudnicki, Miguel A. Andrade
Publikováno v:
FEBS Letters. 579:1795-1801
DNA Microarrays are used to simultaneously measure the levels of thousands of mRNAs in a sample. We illustrate here that a collection of such measurements in different cell types and states is a sound source of functional predictions, provided the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8c45002285cf00206f5e830e6b6350
https://doi.org/10.1016/j.febslet.2005.02.020
https://doi.org/10.1016/j.febslet.2005.02.020
Autor:
Pearl A. Campbell
Publikováno v:
BIO-PROTOCOL. 4
[Abstract] Two main features characterize pluripotent cells; self-renewal (unlimited cell division) and the ability to give rise to all cells of the adult organism. Given the recent impact of induced pluripotent stem cells (iPSCs) and ongoing use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e419012bda97fcf0428b6add8681b7
https://doi.org/10.21769/bioprotoc.1060
https://doi.org/10.21769/bioprotoc.1060