Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Peadar Rooney"'
Autor:
Christina N.M. Ryan, Eugenia Pugliese, Naledi Shologu, Diana Gaspar, Peadar Rooney, Md Nahidul Islam, Alan O'Riordan, Manus J. Biggs, Matthew D. Griffin, Dimitrios I. Zeugolis
Publikováno v:
Biomaterials and Biosystems, Vol 11, Iss , Pp 100079- (2023)
Due to their inherent plasticity, dermal fibroblasts hold great promise in regenerative medicine. Although biological signals have been well-established as potent regulators of dermal fibroblast function, it is still unclear whether physiochemical cu
Externí odkaz:
https://doaj.org/article/0c197c3228874bf5bd13c62a5869656e
Autor:
Jonathan McGrath, Claire Kenny, Charlotte Salgaard Nielsen, Lisa Domegan, Cathal Walsh, Peadar Rooney, Shane Walsh, Niall Conlon, Gareth Brady, Aya Ibrahim, Jean Dunne, William McCormack, Niamh Corcoran, Niamh Allen, Catherine Fleming, Colm Bergin
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundThe PRECISE Study, a multi-phase cross-sectional seroprevalence study of anti-SARS-CoV-2 antibodies in Irish healthcare workers (HCW) investigated: (1) risk factors for SARS-CoV-2 seropositivity, (2) the durability of antibody responses in
Externí odkaz:
https://doaj.org/article/82273f15d7b64ba3bad60c1ed73178a1
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Aims: To examine the effect of three commercial intravesical formulations of glycosaminoglycan on in vitro inflammatory models of IC/BPS to better understand there effect on specific markers of disease.Methods: Human urothelial cells (HTB-4) were cul
Externí odkaz:
https://doaj.org/article/e44ddc95cd124921a31b287747c43c32
Autor:
Christina N.M. Ryan, Eugenia Pugliese, Naledi Shologu, Diana Gaspar, Peadar Rooney, Md Nahidul Islam, Alan O'Riordan, Manus J. Biggs, Matthew D. Griffin, Dimitrios I. Zeugolis
Publikováno v:
Biomaterials advances. 144
Modern bioengineering utilises biomimetic cell culture approaches to control cell fate during in vitro expansion. In this spirit, herein we assessed the influence of bidirectional surface topography, substrate rigidity, collagen type I coating and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b9cb2b27cfef257ecb90e06115fa44
https://pubmed.ncbi.nlm.nih.gov/36455498
https://pubmed.ncbi.nlm.nih.gov/36455498
Autor:
K. Vijaya Krishna, Abhay Pandit, Gandhi Sivaraman, Aitor Larrañaga, Yury Rochev, Niranjan G. Kotla, Peadar Rooney, Bhargavi Chandrasekar
Publikováno v:
ACS biomaterials scienceengineering. 3(7)
Clinical utility of conventional oral therapies is limited by their inability to deliver therapeutic molecules at the local or targeted site, causing a variety of side effects. Transdermal delivery has made a significant contribution in the managemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1332eb26d100d9127c83529778cff34d
https://pubmed.ncbi.nlm.nih.gov/33440514
https://pubmed.ncbi.nlm.nih.gov/33440514
Autor:
Yury Rochev, Niranjan G. Kotla, Ana Benito, Vijaya Krishna Kannala, Leo R. Quinlan, Iraida Loinaz, Abhay Pandit, Damien Dupin, Peadar Rooney
Publikováno v:
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Interstitial cystitis (IC) is a progressive bladder disease characterized by increased urothelial permeability, inflammation of the bladder with abdominal pain. While there is no consensus on the etiology of the disease, it was believed that restorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9dac29699c4d246a8ea1cc37f256e25
https://pubmed.ncbi.nlm.nih.gov/33103826
https://pubmed.ncbi.nlm.nih.gov/33103826
Autor:
Alan O'Riordan, Christina N. M. Ryan, Matthew D. Griffin, N. Islam, Manus J.P. Biggs, Peadar Rooney, Naledi Shologu, Diana Gaspar, Dimitrios I. Zeugolis, Eugenia Pugliese
Publikováno v:
Materials Today Bio, Vol 12, Iss, Pp 100130-(2021)
Materials Today Bio
Materials Today Bio
During in vitro culture, bereft of their optimal tissue context, tenocytes lose their phenotype and function. Considering that tenocytes in their native tissue milieu are exposed simultaneously to manifold signals, combination approaches (e.g. growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86982f80490d8d03327490a31e4f7352
https://doi.org/10.1016/j.mtbio.2021.100130
https://doi.org/10.1016/j.mtbio.2021.100130
Publikováno v:
Biomaterials. 123:127-141
Without an appropriate disease model, the understanding of the pathophysiology of intervertebral disc degeneration and inflammation is limited. The lack of understanding limits the potential discovery of therapeutic targets as viable treatment option
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b7e7fa54af1df3926fb171a0d47660
https://doi.org/10.1016/j.biomaterials.2017.01.045
https://doi.org/10.1016/j.biomaterials.2017.01.045
Autor:
Pedro U. Muñoz-González, Laura E. Castellano, Mauricio Flores-Moreno, Isma Liza Mohd Isa, Jorge Delgado, Abhay Pandit, Birzabith Mendoza-Novelo, Peadar Rooney
Publikováno v:
Biomaterials science. 7(11)
Immunomodulatory biomaterials have emerged as a promising approach to engineer wound healing. To achieve this task, the bioactivity of the biomaterials and an easy application are two key desirable characteristics. This work reports an injectable gel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8d7393b9a972ce5e644b4d3bcd82ce
https://pubmed.ncbi.nlm.nih.gov/31463512
https://pubmed.ncbi.nlm.nih.gov/31463512
Autor:
Danielle Molloy, Peadar Rooney, Mary Connolly, Ursula Fearon, Geraldine M. McCarthy, Douglas J. Veale, Lorraine O'Neill, Conor Murphy, J. McCormick, Eamonn S. Molloy
Publikováno v:
Arthritis & Rheumatology. 67:2447-2456
Objective Giant cell arteritis (GCA) is pathologically characterized by dysfunctional angiogenesis and inflammatory cell infiltration. Acute-phase serum amyloid A (A-SAA) is an acute-phase reactant, but is also produced at sites of inflammation and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6376c0b3d5f2f412d77117f6e23f7c1
https://doi.org/10.1002/art.39217
https://doi.org/10.1002/art.39217