Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Pcnsl (Ml)"'
Autor:
Ohka, Fumiharu, Yamaguchi, Junya, Motomura, Kazuya, Aoki, Kosuke, Nishikawa, Tomohide, Kibe, Yuji, Yamazaki, Shintaro, Natsume, Atsushi, Saito, Ryuta
Publikováno v:
Neuro-oncology Advances
Since 2020, tirabrutinib which is a Bruton’s tyrosine kinase (BTK) inhibitor has been available for recurrent or refractory PCNSL cases. The number of studies reporting efficiency and adverse effect of tirabrutinib treatment for recurrent or refrac
Publikováno v:
Neuro-oncology Advances
Background: Primary central nervous system lymphoma (PCNSL) is a lymphoma whose primary lesion is localized in the brain and spinal cord. Treatment is a combination of high-dose methotrexate-based chemotherapy and whole-brain irradiation, often leadi
Autor:
Sho Onodera, Jiro Akimoto
Publikováno v:
Neuro-oncology Advances
Tirabrutinib (TIR), a Burton’s tyrosine kinase inhibitory drug, has been approved in Japan for treating relapsed/refractory primary central nervous system lymphoma (PCNSL). The authors recently encountered three patients with newly diagnosed refrac
Autor:
Sasaki, Nobuyoshi, Kobayashi, Keiichi, Saito, Kuniaki, Onoda, Ryo, Seiya, Yosuke, Suzuki, Saki, Yamagishi, Yuki, Nakatomi, Hirofumi, Shiokawa, Yoshiaki, Nagane, Motoo
Publikováno v:
Neuro-oncology Advances
BACKGROUNDS: Tirabrutinib is a second-generation Bruton’s tyrosine kinase (BTK) inhibitor, approved by the Japanese Pharmaceutical and Medical Devices Agency (PMDA) for relapsed and refractory PCNSL in March 2020. Skin-related disorder (SRD)s are t
Autor:
Mitsuya, Koichi, Deguchi, Shoichi, Muto, Manabu, Yasui, Kazuaki, Onoe, Tsuyoshi, Ogawa, Hirofumi, Hayashi, Kenji, Asakura, Hirofumi, Harada, Hideyuki, Hayashi, Nakamasa
Publikováno v:
Neuro-oncology Advances
BACKGROUND: Large brain metastases which require resection are treated with surgery followed by whole brain radiation therapy or postoperative stereotactic radiosurgery (SRS). Recently a novel strategy using neoadjuvant stereotactic radiosurgery (Na-
Publikováno v:
Neuro-oncology Advances
The majority of primary central nerve system (CNS) lymphomas (PCNSL) are diffuse large B-cell lymphomas. Anaplastic large cell lymphoma (ALCL) that is a type of T-cell tumor is very rare in the PCNSL. ALCLs are divided into two entities: anaplastic l
Autor:
Masasuke Ohno, Syunichiro Kuramitsu, Syohei Ito, Masayuki Kimata, Takumi Asai, Noriyuki Suzaki, Yasukazu Kajita, Tastuo Takahashi
Publikováno v:
Neuro-oncology Advances
Background: Although the risk of developing malignant lymphoma is higher in patients with rheumatoid arthritis (RA) than in the general population, the occurrence of primary central nervous system lymphoma (PCNSL) in patients with RA is extremely rar
Autor:
Mishima, Kazuhiko, Mitsuaki, Shirahata, Adachi, Junichi, Suzuki, Tomonari, Uchida, Eita, Nishikawa, Ryo
Publikováno v:
Neuro-oncology Advances
BACKGROUND: The prognosis of relapsed and refractory (r/r) primary CNS lymphoma (PCNSL) is poor, and the development of new therapeutic agents is desirable. Comprehensive genetic analysis of PCNSL has shown that MYD88 and CD79B are frequently mutated
Autor:
Hashiba, Tetsuo, Ueno, Katsuya, Naito, Nobuaki, Yamamura, Natsumi, Komori, Yumiko, Isozaki, Haruna, Lee, Ichi, Kamei, Takamasa, Takeda, Junnichi, Yoshimura, Kunikazu, Nonaka, Masahiro, Asai, Akio
Publikováno v:
Neuro-oncology Advances
Last year, the authors examined the outcome of the patients with metastatic brain tumor (MBT)treated by whole-brain irradiation (WBRT)or local irradiation (LRT)after surgery. As a result, it was shown that the overall survival (OS) was same but the r
Autor:
Yamagishi Yuki, Nobuyoshi Sasaki, Yuko Matsushita, Saki Shimizu, Yoshie Matsumoto, Kuniaki Saito, Keiichi Kobayashi, Hirofumi Nakatomi, Yoshiaki Shiokawa, Koichi Ichimura, Motoo Nagane
Publikováno v:
Neuro-oncology Advances
Background: Treatment intervention for central nervous system lymphoma (CNSL) requires pathological diagnosis by surgical biopsy. However, there are some cases in which the risk of surgery is high due to age, comorbidities, localization of lesions, e