Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pazhani Sundaram"'
Publikováno v:
HSOA journal of alzheimer's & neurodegenerative diseases
Alzheimer's disease (AD) is the most common cause of dementia, characterized by the deposition of Amyloid-beta (Aβ) plaques in the brain. We have previously developed Amytrap peptide (the active pharmacological ingredient, API) and linked it to a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799e7d817b06dba6eb5452b8099bcee0
http://europepmc.org/articles/PMC8612462
http://europepmc.org/articles/PMC8612462
Autor:
Omkar Gandbhir, Pazhani Sundaram
Publikováno v:
Journal of Alzheimer's Disease Reports
Alzheimer’s disease (AD) is the most common cause of dementia. Amyloid-β (Aβ42) is implicated in AD pathogenesis. We have designed a non-immune based proprietary therapeutic, called Amytrap, a conjugate containing a retro-inverso peptide, polyeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdb7997c0eba8e4950c2bab2a6e8044
http://europepmc.org/articles/PMC6597960
http://europepmc.org/articles/PMC6597960
Autor:
Pazhani Sundaram, Omkar Gandbhir
Publikováno v:
Journal of Alzheimer's Disease Reports
Alzheimer’s disease (AD) is the most common cause of dementia among elderly patients afflicted by neurodegenerative diseases, caused by the accumulation of amyloid-β (Aβ). Therapeutic interventions in targeting and restricting Aβ production resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537163750ce7ef618f5962d94cdacbd9
https://doi.org/10.3233/adr-180093
https://doi.org/10.3233/adr-180093
Autor:
Pazhani Sundaram, Omkar Gandbhir
Publikováno v:
Metab Brain Dis
Alzheimer’s Disease (AD) is the most common cause of dementia, affecting 25 million people worldwide. Accumulation of Amyloid-β (Aβ) in the mitochondria has been shown to adversely affect key enzymes including pyruvate dehydrogenase (PDH), succin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10f77df8d89cef4077e4f4dcba25a56
https://pubmed.ncbi.nlm.nih.gov/32367269
https://pubmed.ncbi.nlm.nih.gov/32367269
Autor:
Pazhani, Sundaram
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1853
Staining of proteins separated on gels provides the basis for determination of the critical properties of these biopolymers, such as their molecular weight and/or charge. Detection of proteins on gels and blots require stains. These stains vary in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb60ae2d6306946381d2d2178478a783
https://pubmed.ncbi.nlm.nih.gov/30097923
https://pubmed.ncbi.nlm.nih.gov/30097923
Autor:
Pazhani Sundaram
Publikováno v:
Methods in Molecular Biology ISBN: 9781493987443
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2839713cc0a9f5c8828784b1b8d6b53
https://doi.org/10.1007/978-1-4939-8745-0_1
https://doi.org/10.1007/978-1-4939-8745-0_1
Autor:
Pazhani Sundaram
Publikováno v:
Brain and Nerves. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fcfc7d59f7497ad3448646e498b843f
https://doi.org/10.15761/jbn.1000114
https://doi.org/10.15761/jbn.1000114
Publikováno v:
International Journal of Peptide Research and Therapeutics. 18:99-106
Alzheimer's Disease (AD), a debilitating neurodegenerative disease is caused by aggregation and accumulation of a 39-43 amino acid peptide (amyloid β or Aβ) in brain parenchyma and cerebrovasculature. The rational approach would be to use drugs tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfabe8037b28f388ffaa0283bc15e52f
https://doi.org/10.1007/s10989-011-9283-7
https://doi.org/10.1007/s10989-011-9283-7
Publikováno v:
Current Alzheimer Research. 5:26-32
Alzheimers Disease (AD) is caused by the deposition of insoluble and toxic amyloid peptides (Aβ) in the brain leading to memory loss and other associated neurodegenerative symptoms. To date there is limited treatment options and strategies for treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b77492f2971658293e3d22dc1cd004e
https://doi.org/10.2174/156720508783884684
https://doi.org/10.2174/156720508783884684
Publikováno v:
Recent patents on CNS drug discovery. 9(2)
The primary objective of this article is to review patents and the related scientific work on naturally occurring compounds, heterocyclic compounds and small peptides that are being explored for their utility for the treatment of Alzheimer's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fa13524143e0317410c92f6d8494d0
https://pubmed.ncbi.nlm.nih.gov/25244580
https://pubmed.ncbi.nlm.nih.gov/25244580