A phase 2b, Randomized, double blinded comparison of the safety and efficacy of the monoclonal antibody mixture SYN023 and human rabies immune globulin in patients exposed to rabies.

Autor: Quiambao BP; Research Institute for Tropical Medicine Filinvest Corporate City, Muntinlupa City, Metro Manila, Philippines., Payumo RA; Mary Johnston Hospital, Tondo Manila, Metro Manila, Philippines., Roa C; Manila Doctors Hospital, Ermita Manila, Metro Manila, Philippines., Borja-Tabora CF; Center of Excellence in Drug Research, Evaluation and Studies, Inc., Filinvest Corporate City, Muntinlupa City, Metro Manila, Philippines., Emmeline Montellano M; Far Eastern University - Nicanor Reyes Medical Foundation, Quezan City, Metro Manila, Philippines., Reyes MRL; Research Institute for Tropical Medicine Filinvest Corporate City, Muntinlupa City, Metro Manila, Philippines., Zoleta-De Jesus L; Angelo King Medical Research Center, De la Salle Health Sciences Institute, Dasmarinas City, Cavite, Philippines., Capeding MR; Asian Hospital and Medical Center, Muntinlupa City, Metro Manila, Philippines., Solimen DP; Baguio General Hospital and Medical Center, Baguio City, Cordillera Administrative Region, Philippines., Barez MY; Southern Philippines Medical Center, Dermatology Clinical Research Unit, Davao City, Davao Region (Region XI), Philippines., Reid C; Synermore Biologics (Suzhou) Co., Ltd, Suzhou Industrial Park, China., Chuang A; Synermore Biologics (Suzhou) Co., Ltd, Suzhou Industrial Park, China., Tsao E; Synermore Biologics (Suzhou) Co., Ltd, Suzhou Industrial Park, China. Electronic address: etsao@synermore.com., McClain JB; Synermore Biologics (Suzhou) Co., Ltd, Suzhou Industrial Park, China.

Publikováno v: Vaccine [Vaccine] 2024 Sep 17; Vol. 42 (22), pp. 126018. Date of Electronic Publication: 2024 Jun 04.