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Akademický článek

Comprehensive assessment of blood–brain barrier opening and sterile inflammatory response: unraveling the therapeutic window

Autor: Payton J. Martinez, Jane J. Song, Francis G. Garay, Kang-Ho Song, Toni Mufford, Jenna Steiner, John DeSisto, Nicholas Ellens, Natalie J. Serkova, Adam L. Green, Mark Borden

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Microbubbles (MBs) combined with focused ultrasound (FUS) has emerged as a promising noninvasive technique to permeabilize the blood–brain barrier (BBB) for drug delivery into the brain. However, the safety and biological consequences of B

Externí odkaz: https://doaj.org/article/76f1eee73d994c8498282e6b889d7fd8

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Akademický článek

Comprehensive assessment of blood–brain barrier opening and sterile inflammatory response: unraveling the therapeutic window.

Autor: Martinez, Payton J.¹ (AUTHOR), Song, Jane J.¹ (AUTHOR), Garay, Francis G.² (AUTHOR), Song, Kang-Ho³ (AUTHOR), Mufford, Toni² (AUTHOR), Steiner, Jenna² (AUTHOR), DeSisto, John⁴ (AUTHOR), Ellens, Nicholas⁵ (AUTHOR), Serkova, Natalie J.² (AUTHOR), Green, Adam L.⁴ (AUTHOR), Borden, Mark^1,3 (AUTHOR) mark.borden@colorado.edu

Publikováno v: Scientific Reports. 7/24/2024, Vol. 14 Issue 1, p1-15. 15p.

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Akademický článek

Negative Pressure Wound Therapy with Instillation for Periprosthetic Infection after Breast Reconstruction: A Systematic Review

Autor: Madeline J. O’Connor, BA, Kristin N. Huffman, BS, Kelly Ho, BS, Sammer Marzouk, MA, Rolando J. Casas Fuentes, BS, Kenneth L. Zhang, BS, Bradley A. Melnick, BS, Payton J. Sparks, BS, Raiven Harris, BA, Angelica V. Bartler, MS, Ashley Collinsworth, ScD, MPH, Leah Griffin, MS, Robert D. Galiano, MD, FACS

Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 11, p e6267 (2024)

Background:. Periprosthetic infection after breast reconstruction is not uncommon and can result in loss of the implant pocket and negative patient outcomes. Management of these infections typically involves removal of the prosthesis, treatment with

Externí odkaz: https://doaj.org/article/d9853d1816a04a8b87f92d7fee33e922

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BioSimulators: a central registry of simulation engines and services for recommending specific tools

Autor: Shaikh, Bilal, Smith, Lucian P., Vasilescu, Dan, Marupilla, Gnaneswara, Wilson, Michael, Agmon, Eran, Agnew, Henry, Andrews, Steven S., Anwar, Azraf, Beber, Moritz E., Bergmann, Frank T., Brooks, David, Brusch, Lutz, Calzone, Laurence, Choi, Kiri, Cooper, Joshua, Detloff, John, Drawert, Brian, Dumontier, Michel, Ermentrout, G. Bard, Faeder, James R., Freiburger, Andrew P., Fröhlich, Fabian, Funahashi, Akira, Garny, Alan, Gennari, John H., Gleeson, Padraig, Goelzer, Anne, Haiman, Zachary, Hellerstein, Joseph L., Hoops, Stefan, Ison, Jon C., Jahn, Diego, Jakubowski, Henry V., Jordan, Ryann, Kalaš, Matúš, König, Matthias, Liebermeister, Wolfram, Mandal, Synchon, McDougal, Robert, Medley, J. Kyle, Mendes, Pedro, Müller, Robert, Myers, Chris J., Naldi, Aurelien, Nguyen, Tung V. N., Nickerson, David P., Olivier, Brett G., Patoliya, Drashti, Paulevé, Loïc, Petzold, Linda R., Priya, Ankita, Rampadarath, Anand K., Rohwer, Johann M., Saglam, Ali S., Singh, Dilawar, Sinha, Ankur, Snoep, Jacky, Sorby, Hugh, Spangler, Ryan, Starruß, Jörn, Thomas, Payton J., van Niekerk, David, Weindl, Daniel, Zhang, Fengkai, Zhukova, Anna, Goldberg, Arthur P., Blinov, Michael L., Sauro, Herbert M., Moraru, Ion I., Karr, Jonathan R.

Computational models have great potential to accelerate bioscience, bioengineering, and medicine. However, it remains challenging to reproduce and reuse simulations, in part, because the numerous formats and methods for simulating various subsystems

Externí odkaz: http://arxiv.org/abs/2203.06732