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A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and Is Upregulated during Hypoxia and Aging.

Autor: Payne LB; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Abdelazim H; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Hoque M; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Barnes A; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA.; Department of Biomedical Engineering and Mechanics, School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USA., Mironovova Z; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Willi CE; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Darden J; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Houk C; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; Virginia Tech Carilion School of Medicine, Roanoke, VA 24016, USA., Sedovy MW; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA., Johnstone SR; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA.; Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, USA., Chappell JC; Fralin Biomedical Research Institute (FBRI) at Virginia Tech-Carilion (VTC), Roanoke, VA 24016, USA.; FBRI Center for Vascular and Heart Research, Roanoke, VA 24016, USA.; Department of Biomedical Engineering and Mechanics, School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 24061, USA.; Virginia Tech Carilion School of Medicine, Roanoke, VA 24016, USA.

Publikováno v: Biomolecules [Biomolecules] 2023 Apr 21; Vol. 13 (4). Date of Electronic Publication: 2023 Apr 21.

Connexin 43 across the Vasculature: Gap Junctions and Beyond.

Autor: Sedovy MW; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA.; Translational Biology, Medicine, And Health Graduate Program, Virginia Tech, Blacksburg, Virginia, USA., Leng X; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA., Leaf MR; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA.; Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA., Iqbal F; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA.; Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA., Payne LB; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA., Chappell JC; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA., Johnstone SR; The Fralin Biomedical Research Institute at Virginia Tech Carilion, Center for Vascular and Heart Research, 4 Riverside Circle, Roanoke, Virginia, USA.; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA.

Publikováno v: Journal of vascular research [J Vasc Res] 2023; Vol. 60 (2), pp. 101-113. Date of Electronic Publication: 2022 Dec 13.

Pericyte Progenitor Coupling to the Emerging Endothelium During Vasculogenesis via Connexin 43.

Autor: Payne LB; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.)., Tewari BP; Department of Neuroscience, University of Virginia, Charlottesville (B.P.T., H.S.)., Dunkenberger L; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.)., Bond S; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.)., Savelli A; Virginia Tech Carilion School of Medicine, Roanoke (A.S., J.C.C.)., Darden J; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.).; Graduate Program in Translational Biology, Medicine and Health (J.D.), Virginia Tech, Blacksburg., Zhao H; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.).; Department of Biomedical Engineering and Mechanics (H.Z., J.C.C.), Virginia Tech, Blacksburg., Willi C; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.)., Kanodia R; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.)., Gude R; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.)., Powell MD; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus (M.D.P., K.J.O.)., Oestreich KJ; Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus (M.D.P., K.J.O.)., Sontheimer H; Department of Neuroscience, University of Virginia, Charlottesville (B.P.T., H.S.)., Dal-Pra S; Division of Cardiovascular Medicine and Mandel Center for Hypertension Research (S.D.-P.), Duke University Medical Center, Durham, NC.; Division of Cardiovascular Medicine, Department of Medicine (S.D.-P.), Duke University Medical Center, Durham, NC., Chappell JC; Center for Vascular and Heart Research, Fralin Biomedical Research Institute at Virginia Tech-Carilion, Roanoke (L.B.P., L.D., S.B., A.S., J.D., H.Z., C.W., R.K., R.G., J.C.C.).; Virginia Tech Carilion School of Medicine, Roanoke (A.S., J.C.C.).; Department of Biomedical Engineering and Mechanics (H.Z., J.C.C.), Virginia Tech, Blacksburg.

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2022 Apr; Vol. 42 (4), pp. e96-e114. Date of Electronic Publication: 2022 Feb 10.