Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Payne Andrew H"'
Publikováno v:
Organic Process Research & Development. 25:2277-2287
Autor:
Payne Andrew H, Christopher McKay, Peter R. Clark, Anna L. Dunn, Kevin Arendt, Susan Shilcrat, Katherine Wheelhouse, Frank Dixon, Glynn D. Williams
Publikováno v:
Journal of Chemical Education. 98:175-182
Awareness of best safety practices in the industrial sector will allow students in chemistry and chemical engineering programs to apply these approaches to their own safety assessments. Process safety is a critical function within the pharmaceutical
Autor:
Magnus, Philip, Gazzard, Lewis, Hobson, Lindsay, Payne, Andrew H., Rainey, Trevor J., Westlund, Neil, Lynch, Vince
Publikováno v:
In Tetrahedron 2002 58(17):3423-3443
Publikováno v:
In Tetrahedron Letters 1999 40(28):5135-5138
Autor:
Ellard, John M., Madin, Andrew, Philps, Oliver, Hopkin, Mark, Henderson, Scott, Birch, Louise, O’Connor, Desmond, Arai, Tohru, Takase, Kazuma, Morgan, Louise, Reynolds, David, Talma, Sonia, Howley, Eimear, Powney, Ben, Payne, Andrew H., Hall, Adrian, Gartlon, Jane E., Dawson, Lee A., Castro, Luis, Atkinson, Peter J.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 December 2015 25(24):5792-5796
Autor:
Payne Andrew H, Adam Hold, Graham Trevitt, Jeremy Martin Davis, Chloe Edwards, Clare Watkins, Brian Hutchinson, Daniel James Ford, Rachel A. Garlish, John Robert Porter, James D. Turner, Ian Whitcombe, Colin Stubberfield, Ben de Candole
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1767-1772
The separation of atropisomeric conformers of 1,2,3,4-tetrahydroisoquinoline amide Bcl-2 ligands allowed the identification of the bioactive conformer which was subsequently confirmed by X-ray crystallography.
Publikováno v:
Angewandte Chemie. 120:5138-5140
Autor:
Martyn D. Wood, Daniele Donati, Steve P. Watson, Claire M. Howes, Payne Andrew H, Patrick M. Woollard, Silvia Terreni, Romano Di Fabio, Ian Peter Holmes, Charlie Reavill, Andy Gribble, Angela Worby, Richard Blunt, Luca Arista, Stephen M. Blowers, Olivier Lorthioir, Dieter Hamprecht, Ian Stansfield, Fabrizio Micheli
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(6)
The identification of a highly selective D 2 partial agonist, D 3 antagonist tool molecule which demonstrates high levels of brain exposure and selectivity against an extensive range of dopamine, serotonin, adrenergic, histamine, and muscarinic recep
Autor:
Malcom Meeson, Daniele Donati, Sara E. Douglas, Declan N.C. Jones, Payne Andrew H, Jim J. Hagan, Martyn D. Wood, Mike S. Hadley, Ian Thomson Forbes, Angela Worby, Emma E. Dodds, Andrew P. Lightfoot, Peter Eddershaw, Chris Ioannou, Charlie Reavill, David Gwyn Cooper, E. Ratti, Ian Stansfield, Alexander Baxter Smith, Andrew Derrick Gribble, Carol A. Scorer, Vincenzo Garzya, Graham J. Riley
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(2)
A rational structure-activity relationship study around compound (1) is reported. The lead optimisation programme led to the identification of sulfonamide (25), a molecule combining dopamine D2/D3 receptor antagonism with serotonin 5-HT2A, 5-HT2C, 5-
Autor:
Holmes, Ian P., Blunt, Richard J., Lorthioir, Olivier E., Blowers, Stephen M., Gribble, Andy, Payne, Andrew H., Stansfield, Ian G., Wood, Martyn, Woollard, Patrick M., Reavill, Charlie, Howes, Claire M., Micheli, Fabrizio, Fabio, Romano Di, Donati, Daniele, Terreni, Silvia, Hamprecht, Dieter, Arista, Luca, Worby, Angela, Watson, Steve P.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2010 20(6):2013-2016