Zobrazeno 1 - 10
of 397
pro vyhledávání: '"Payne, Philip R. O."'
Autor:
Dong, Zehao, Zhao, Qihang, Payne, Philip R. O., Province, Michael A, Cruchaga, Carlos, Zhang, Muhan, Zhao, Tianyu, Chen, Yixin, Li, Fuhai
Biomarker identification is critical for precise disease diagnosis and understanding disease pathogenesis in omics data analysis, like using fold change and regression analysis. Graph neural networks (GNNs) have been the dominant deep learning model
Externí odkaz:
http://arxiv.org/abs/2402.07268
Autor:
Dong, Zehao, Zhang, Muhan, Payne, Philip R. O., Province, Michael A, Cruchaga, Carlos, Zhao, Tianyu, Li, Fuhai, Chen, Yixin
The expressivity of Graph Neural Networks (GNNs) has been studied broadly in recent years to reveal the design principles for more powerful GNNs. Graph canonization is known as a typical approach to distinguish non-isomorphic graphs, yet rarely adopt
Externí odkaz:
http://arxiv.org/abs/2309.00738
Publikováno v:
Cancers 2023, 15(17), 4210
Synergistic drug combinations provide huge potentials to enhance therapeutic efficacy and to reduce adverse reactions. However, effective and synergistic drug combination prediction remains an open question because of the unknown causal disease signa
Externí odkaz:
http://arxiv.org/abs/2209.09245
Autor:
Kumar, Sayantan, Yu, Sean C., Kannampallil, Thomas, Abrams, Zachary, Michelson, Andrew, Payne, Philip R. O.
Complex deep learning models show high prediction tasks in various clinical prediction tasks but their inherent complexity makes it more challenging to explain model predictions for clinicians and healthcare providers. Existing research on explainabi
Externí odkaz:
http://arxiv.org/abs/2110.04598
Autor:
Kumar, Sayantan, Oh, Inez, Schindler, Suzanne, Lai, Albert M, Payne, Philip R O, Gupta, Aditi
Publikováno v:
JAMIA Open, Volume 4, Issue 3, July 2021, ooab052
Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of studies that
Externí odkaz:
http://arxiv.org/abs/2108.04174
The Coronavirus Disease 2019 (COVID-19) pandemic has infected over 10 million people globally with a relatively high mortality rate. There are many therapeutics undergoing clinical trials, but there is no effective vaccine or therapy for treatment th
Externí odkaz:
http://arxiv.org/abs/2006.01226
Akademický článek
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Akademický článek
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Drug resistance is still a major challenge in cancer therapy. Drug combination is expected to overcome drug resistance. However, the number of possible drug combinations is enormous, and thus it is infeasible to experimentally screen all effective dr
Externí odkaz:
http://arxiv.org/abs/1811.07054
Examining heterogeneity in dementia using data-driven unsupervised clustering of cognitive profiles.
Autor:
Kumar, Sayantan, Oh, Inez Y., Schindler, Suzanne E., Ghoshal, Nupur, Abrams, Zachary, Payne, Philip R. O.
Publikováno v:
PLoS ONE; 11/14/2024, Vol. 19 Issue 11, p1-19, 19p
