Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Payman Hanifi-Moghaddam"'
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Progesterone Receptor-B Induction of BIRC3 Protects Endometrial Cancer Cells from AP1-59-Mediated Apoptosis
Autor: Parin Patel, Leen J. Blok, Zhenxiao Lu, Nikki L. Neubauer, Irene I. Lee, Payman Hanifi-Moghaddam, Erin C. Ward, Julian C. Schink, J. Julie Kim
Publikováno v: Hormones and Cancer, 2(3), 170-181. Springer Publishing Company
Progesterone is a growth inhibitory hormone in the endometrium. While progestins can be used for the treatment of well-differentiated endometrial cancers, resistance to progestin therapy occurs for reasons that remain unclear. We have previously demo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bb9fd7aa51e59f7a85af66a2f9cf02
https://doi.org/10.1007/s12672-011-0065-7
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5
Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle
Autor: Miriam B. Buck, Simone L. Popp, Curt W. Burger, Peter Fritz, Cornelius Knabbe, Ina S. Abele, Leen J. Blok, Payman Hanifi-Moghaddam, Matthias B. Stope
Publikováno v: Journal of Molecular Histology, 41(2-3), 111-119. Springer Netherlands
We have shown previously that high expression levels of microsomal epoxide hydrolase (mEH) correlate with a poor prognosis of breast cancer patients receiving tamoxifen, suggesting that enhanced mEH expression could lead to antiestrogen resistance (F
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc72d91267ff964f79cc6639d5c5fb38
https://doi.org/10.1007/s10735-010-9266-6
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6
Signaling by estrogens and tamoxifen in the human endometrium
Autor: Susanne C.J.P. Gielen, Lindy A.M. Santegoets, Leen J. Blok, Payman Hanifi-Moghaddam, Curt W. Burger
Publikováno v: Journal of Steroid Biochemistry and Molecular Biology, 109(3-5), 219-223. Elsevier Ltd.
Tamoxifen is used as adjuvant treatment for postmenopausal breast cancer patients. The mechanism of action of tamoxifen in breast cancer patients is that tamoxifen inhibits growth of cancer cells by competitive antagonism for estrogens at the estroge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b419fe4dad718258bc9b5370462e63cb
https://doi.org/10.1016/j.jsbmb.2008.03.021
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7
Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina
Autor: Bianca Boers-Sijmons, Helenius J. Kloosterboer, Anet H.A. Klaassens, Curt W. Burger, Peter J. van der Spek, Leen J. Blok, Wilfred F. J. van IJcken, Payman Hanifi-Moghaddam, F. Heidy van Wijk, Herman A. M. Verheul
Publikováno v: Human Reproduction, 23(2), 298-305. Oxford University Press
textabstractBACKGROUND: Combined hormone treatments in post-menopausal women have different clinical responses on uterus and vagina; therefore, we investigated differences in steroid signalling between various hormone therapies in these tissues. METH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b35fb5040abe04c47834e347b54cf3
https://hdl.handle.net/1765/15100
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8
The regulation and function of the forkhead transcription factor, forkhead box O1, is dependent on the progesterone receptor in endometrial carcinoma
Autor: Anna V. Hoekstra, Diljeet K. Singh, Barbara M. Buttin, Leen J. Blok, Julian C. Schink, J. Julie Kim, Erin C. Ward, Payman Hanifi-Moghaddam, John R. Lurain
Publikováno v: Endocrinology, 149(4), 1942-1950. Endocrine Society
In many type I endometrial cancers, the PTEN gene is inactivated, which ultimately leads to constitutively active Akt and the inhibition of Forkhead box O1 (FOXO1), a member of the FOXO subfamily of Forkhead/winged helix family of transcription facto
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1629fe6667be8d7eb0c905a0fac06b81
https://hdl.handle.net/1765/28983
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9
HPV related VIN: Highly proliferative and diminished responsiveness to extracellular signals
Autor: Wilfred F. J. van IJcken, Lindy A.M. Santegoets, Manon van Seters, Patricia C. Ewing, Leen J. Blok, Theo J.M. Helmerhorst, Payman Hanifi-Moghaddam, Claudia Heijmans-Antonissen, Willem I. van der Meijden, Peter J. van der Spek
Publikováno v: International Journal of Cancer, 121(4), 759-766. Wiley-Liss Inc.
Vulvar intraepithelial neoplasia (VIN) is a premalignant disorder caused by human papillomaviruses. Basic knowledge about the molecular pathogenesis of VIN is sparse. Therefore, we have analyzed the gene expression profile of 9 VIN samples in compari
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb930a005b04a121a45111711d46292
https://doi.org/10.1002/ijc.22769
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10
The hormone replacement therapy drug tibolone acts very similar to medroxyprogesterone acetate in an estrogen-and progesterone-responsive endometrial cancer cell line
Autor: Leen J. Blok, B. Sijmons, M. C. Ott, Payman Hanifi-Moghaddam, D Nowzari, W F J van IJcken, Curt W. Burger, Helenius J. Kloosterboer, E C M Kuhne, P van der Spek
Publikováno v: Journal of Molecular Endocrinology, 37(3), 405-413. Bioscientifica Ltd
Tibolone, a steroidogenic compound with both estrogenic and progestagenic properties, is used as an alternative for estrogen or estrogen plus progesterone hormone therapy for the treatment of symptoms associated with menopause and osteoporosis. We ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65aad5a54a7612971035717b14a6b241
https://doi.org/10.1677/jme.1.02057
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