Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Payel Sil"'
Autor:
Wenling Li, Hideki Nakano, Wei Fan, Yuanyuan Li, Payel Sil, Keiko Nakano, Fei Zhao, Peer W. Karmaus, Sara A. Grimm, Min Shi, Xin Xu, Ryushin Mizuta, Daisuke Kitamura, Yisong Wan, Michael B. Fessler, Donald N. Cook, Igor Shats, Xiaoling Li, Leping Li
Publikováno v:
JCI Insight, Vol 8, Iss 17 (2023)
DNASE1L3, an enzyme highly expressed in DCs, is functionally important for regulating autoimmune responses to self-DNA and chromatin. Deficiency of DNASE1L3 leads to development of autoimmune diseases in both humans and mice. However, despite the wel
Externí odkaz:
https://doaj.org/article/eba649c4683647208269358c9f30e162
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The skin is a highly organized first line of defense that stretches up to 1.8 m2 and is home to more than a million commensal bacteria. The microenvironment of skin is driven by factors such as pH, temperature, moisture, sebum level, oxidative stress
Externí odkaz:
https://doaj.org/article/5ab24d8a67a244528b7e837c6892ff1f
Autor:
Madison Floyd, Matthew Winn, Christian Cullen, Payel Sil, Benoit Chassaing, Dae-Goon Yoo, Andrew T Gewirtz, Joanna B Goldberg, Linda L McCarter, Balázs Rada
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005987 (2016)
Pseudomonas aeruginosa is an opportunistic pathogen causing severe infections often characterized by robust neutrophilic infiltration. Neutrophils provide the first line of defense against P. aeruginosa. Aside from their defense conferred by phagocyt
Externí odkaz:
https://doaj.org/article/2d35d866abed4523b358caf71358d0ad
Autor:
Rachael K. Aquino, Michael Perez, Payel Sil, Terry Shintani, Rosanne Harrigan, Beatriz Rodriguez
Publikováno v:
Geriatrics, Vol 3, Iss 2, p 17 (2018)
In 2010, approximately 79 million Americans had prediabetes and about 50 percent of those individuals were 65 years and older. The most effective diabetes prevention method in prediabetic adults is lifestyle modification. However, despite the benefit
Externí odkaz:
https://doaj.org/article/34666d20da534427800320ca3684a986
Autor:
Cynthia J. Willson, Ginger W. Muse, Page Myers, Payel Sil, Amanda S. MacLeod, Kyathanahalli S. Janardhan, Artiom Gruzdev, Liwen Liu, Jutamas Suwanpradid, Sara A. Grimm, Laura M. DeGraff, David L. Corcoran, Jennifer Martinez
Publikováno v:
Journal of Allergy and Clinical Immunology. 145:1389-1405
Background Control of the inflammatory response is critical to maintaining homeostasis, and failure to do so contributes to the burden of chronic inflammation associated with several disease states. The mechanisms that underlie immunosuppression, how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32aab2bd0c429d2402b93c5831dfb753
https://doi.org/10.1016/j.jaci.2019.11.041
https://doi.org/10.1016/j.jaci.2019.11.041
Autor:
Murray Stackhouse, Mariah Kuta, Joseph Kolb, Sydney Scatigno, Amber Blackwell, Chassidy Hall, Christopher Dowdy, Payel Sil, Diana Gietl, Steve Festin, Paula L. Miliani De Marval
Publikováno v:
Cancer Research. 82:2583-2583
The cancer immunotherapy field has seen an increasing demand for identifying and characterizing pre-clinical models to evaluate the efficacy of the checkpoint inhibitors such as, ipilimumab and pembrolizumab. PBMC- or CD34-humanized mouse models are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::713daca181f256ad12bbf261e5ea85e6
https://doi.org/10.1158/1538-7445.am2022-2583
https://doi.org/10.1158/1538-7445.am2022-2583
Publikováno v:
The FEBS Journal. 285:1379-1388
Rubicon (Rubcn) was initially identified as a component of the Class III PI3K complex and a negative regulator of canonical autophagy and endosomal trafficking. However, Rubicon has attracted the most notoriety because of its critical role in LC3-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd131020b8b1fb1808dd5d4c07989dea
https://doi.org/10.1111/febs.14354
https://doi.org/10.1111/febs.14354
Autor:
Joseph P. Kolb, Erica Scappini, Laura M. DeGraff, Andrew Oberst, Jennifer Martinez, Payel Sil, Ginger W. Muse, Sing-Wai Wong, Sara A. Grimm, Courtney Tucker, Annelise G. Snyder, Zhao F
SummaryMajor Histocompatibility Complex I (MHC-I) molecules classically present peptides derived from endogenous antigens, but exogenous antigens can also gain access to the MHC-I machinery in dendritic cells (DCs), which can activate antigen-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846b5d35275b25b9d63d6d17c61a4495
Publikováno v:
Inflammation Research. 66:227-237
Arthritic gout is caused by joint inflammation triggered by the damaging effects of monosodium uric acid (MSU) crystal accumulation in the synovial space. Neutrophils play a major role in mediating joint inflammation in gout. Along with neutrophils,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51adb2c9230d67b8b1083ce1131f3cb3
https://doi.org/10.1007/s00011-016-1008-0
https://doi.org/10.1007/s00011-016-1008-0
Publikováno v:
Current opinion in immunology. 50
While classically considered a survival mechanism employed during nutrient scarcity, the autophagy pathway operates in multiple scenarios wherein a return to homeostasis or degradative removal of an invader is required. Now recognized as a pathway wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0695ca920b9db6be18ca20af5d4dad63
https://pubmed.ncbi.nlm.nih.gov/29125936
https://pubmed.ncbi.nlm.nih.gov/29125936