Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Payam Mahboubi"'
Restriction Enzyme–Mediated Enhanced Detection of Circulating Cell-Free Fetal DNA in Maternal Plasma
Publikováno v:
The Journal of Molecular Diagnostics. 13:382-389
A universal method confirming the presence of circulating cell-free fetal (ccff) DNA in maternal plasma is important in the field of noninvasive prenatal diagnostics. Restriction endonuclease digestion of one allele of a single-nucleotide polymorphis
Autor:
Daniel T. O'Connor, Geert W. Schmid-Schönbein, Sushil K. Mahata, Nicholas J. Schork, Ryan S. Friese, Nitish R. Mahapatra, Payam Mahboubi
Publikováno v:
American Journal of Hypertension. 18:633-652
Genetic studies of essential hypertension, a complex, polygenic, and age-dependent disorder, have not been able to completely elucidate the genes responsible for development of the trait. We used a novel strategy to compare gene expression in the adr
Autor:
Nicholas J. Schork, Sushil K. Mahata, Ryan S. Fries, Daniel T. O'Connor, Geert W. Schmid-Schoenbein, Nitish R. Mahapatra, Payam Mahboubi
Publikováno v:
Hypertension. 43:1301-1311
The genetic basis of hypertension in the genetically/hereditary hypertensive (BPH/2) mouse strain is incompletely understood, although a recent genome scan uncovered evidence for several susceptibility loci. To probe the neuroendocrine transcriptome
Autor:
Bruce A. Hamilton, Manjula Mahata, Daniel T. O'Connor, Mats Stridsberg, Gen Wen, Fangwen Rao, Peter E. Cadman, Nicholas J. Schork, Nitish R. Mahapatra, Sajalendu Ghosh, Payam Mahboubi, Douglas W. Smith, Sushil K. Mahata
Publikováno v:
The American Journal of Human Genetics. 74(2):197-207
The chromogranin/secretogranin proteins are costored and coreleased with catecholamines from secretory vesicles in chromaffin cells and noradrenergic neurons. Chromogranin A (CHGA) regulates catecholamine storage and release through intracellular (ve
Autor:
Daniel T. O'Connor, Payam Mahboubi, Sushil K. Mahata, Nitish R. Mahapatra, Clifford Wong, Manjula Mahata, Surin Chitbangonsyn
Publikováno v:
Physiological Genomics. 14:83-93
Hypertension is a complex trait with multiple genetic determinants. A previous genome-wide linkage study of systolic blood pressure in a mouse genetic backcross implicated a region of chromosome 13 (LOD = 3.3 at 16.0 cM) as a determinant of blood pre
Autor:
David S. Timberlake, D Walker, S W Chitbangonsyn, Payam Mahboubi, K L Diggle, Robert J. Parmer, Brinda K. Rana, Daniel T. O'Connor
Publikováno v:
Journal of Human Hypertension. 17:319-324
Allelic variation at multiple genetic loci may contribute to hypertension. Since autonomic/sympathetic dysfunction may play an early, pathogenic, heritable role in hypertension, we evaluated candidate loci likely to contribute to such dysfunction, in
Publikováno v:
Genomics. 53(1)
We have developed a rapid screening method for cross-species amplification of homologous microsatellite loci and studied some of the characteristics of those loci in the species of origin (human) and the test species (baboon). We tested a matrix of 6