Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Payam, Mohaghegh"'
Autor:
Michael F. Murphy, Paul Altmann, David Miles, Simon Noel, Stephen P. Hibbs, Payam Mohaghegh, Julie Staves, Caroline E. Butler, Elinor Curnow
Publikováno v:
Transfusion. 55:1964-1971
BACKGROUND There is increasing evidence for restrictive red blood cell (RBC) transfusion but compliance with recommended transfusion triggers is variable. A clinical decision support system (CDSS) has been found to reduce unnecessary transfusion in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81bb7c391836981ff43d815714912354
https://doi.org/10.1111/trf.13075
https://doi.org/10.1111/trf.13075
Autor:
Caroline E, Butler, Simon, Noel, Stephen P, Hibbs, David, Miles, Julie, Staves, Payam, Mohaghegh, Paul, Altmann, Elinor, Curnow, Michael F, Murphy
Publikováno v:
Transfusion. 55(8)
There is increasing evidence for restrictive red blood cell (RBC) transfusion but compliance with recommended transfusion triggers is variable. A clinical decision support system (CDSS) has been found to reduce unnecessary transfusion in some clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccd28cab03f7629e64d4c5175e64d56d
https://pubmed.ncbi.nlm.nih.gov/25906831
https://pubmed.ncbi.nlm.nih.gov/25906831
Publikováno v:
Nucleic Acids Research. 29:2843-2849
BLM and WRN, the products of the Bloom’s and Werner’s syndrome genes, are members of the RecQ family of DNA helicases. Although both have been shown previously to unwind simple, partial duplex DNA substrates with 3′→5′ polarity, little is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5688bd751bed0451cf55f2248e0ca7
https://doi.org/10.1093/nar/29.13.2843
https://doi.org/10.1093/nar/29.13.2843
Autor:
Nicholas Owen, Thanh Le, Chris P. Ponting, Nanda R. Rodrigues, Arthur H.M. Burghes, Kay E. Davies, Payam Mohaghegh
Publikováno v:
European Journal of Human Genetics. 7:519-525
Autosomal recessive childhood onset spinal muscular atrophy (SMA) is a leading cause of infant mortality caused by mutations in the survival motor neuron (SMN) gene. The SMN protein is involved in RNA processing and is localised in structures called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c863a00236b6b1832a2457793bd1fbc
https://doi.org/10.1038/sj.ejhg.5200346
https://doi.org/10.1038/sj.ejhg.5200346
Publikováno v:
Scopus-Elsevier
Mutations in the gene encoding the Survival Motor Neuron (SMN) protein are responsible for autosomal recessive proximal spinal muscular atrophy (SMA). SMN orthologues have been identified in the nematode worm Caenorhabditis elegans and the yeast Schi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a866e9fb231fd589e0965f4b0dd66bad
https://doi.org/10.1093/hmg/7.13.2149
https://doi.org/10.1093/hmg/7.13.2149
Autor:
Payam Mohaghegh, Ian D. Hickson
Publikováno v:
Molecular Mechanisms of Werner’s Syndrome ISBN: 9781461347668
Molecular Mechanisms of Werner’s Syndrome
Molecular Mechanisms of Werner’s Syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5503a7563b118b6b90d11d29d1f45af
https://doi.org/10.1007/978-1-4419-9032-7_2
https://doi.org/10.1007/978-1-4419-9032-7_2
Autor:
Payam Mohaghegh
Premature aging is the earlier than expected onset of age-related deterioration of the physiological functions necessary for the survival and fertility of an organism. Human aging is a polygenic and multifactorial process. However, sometimes the muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac154eb137bf5d976666dfa1c20bcf3
https://doi.org/10.1016/b0-12-475570-4/00053-6
https://doi.org/10.1016/b0-12-475570-4/00053-6
Autor:
Payam, Mohaghegh, Ian D, Hickson
Publikováno v:
Biologist (London, England). 50(1)
Bloom's syndrome, a very rare inherited disorder, predisposes its sufferers to the full range of cancers that afflict humanity. This predisposition is rooted in just one defective gene on chromosome 15. It encodes the BLM helicase - an enzyme that or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37e637d97015ea8225242b87e256ab8f
https://pubmed.ncbi.nlm.nih.gov/12586954
https://pubmed.ncbi.nlm.nih.gov/12586954
Autor:
Ian D. Hickson, Payam Mohaghegh
Publikováno v:
The international journal of biochemistrycell biology. 34(11)
The RecQ family of DNA helicases have potential roles in DNA repair, replication and/or recombination pathways. In humans, a defect in the RecQ family helicases encoded by the BLM, WRN and RECQ4 genes gives rise to Bloom’s (BS), Werner’s (WS) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9db263abf77c9ea6a0a4a12be6a86e
https://pubmed.ncbi.nlm.nih.gov/12200042
https://pubmed.ncbi.nlm.nih.gov/12200042
Autor:
Payam Mohaghegh, Ian D. Hickson
Publikováno v:
Human molecular genetics. 10(7)
Deficiency in a helicase of the RecQ family is found in at least three human genetic disorders associated with cancer predisposition and/or premature ageing. The RecQ helicases encoded by the BLM, WRN and RECQ4 genes are defective in Bloom's, Werner'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b240948b400c8bfb0ad9fc694f3e4be
https://pubmed.ncbi.nlm.nih.gov/11257107
https://pubmed.ncbi.nlm.nih.gov/11257107