Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Payam, Fathi"'
Autor:
Thao D.V. Le, Payam Fathi, Amanda B. Watters, Blair J. Ellis, Gai-Linn K. Besing, Nadejda Bozadjieva-Kramer, Misty B. Perez, Andrew I. Sullivan, Jesse P. Rose, Laurie L. Baggio, Jacqueline Koehler, Jennifer L. Brown, Michelle B. Bales, Kaitlyn G. Nwaba, Jonathan E. Campbell, Daniel J. Drucker, Matthew J. Potthoff, Randy J. Seeley, Julio E. Ayala
Publikováno v:
Molecular Metabolism, Vol 72, Iss , Pp 101718- (2023)
Objective: Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1RA) and fibroblast growth factor-21 (FGF21) confer similar metabolic benefits. GLP-1RA induce FGF21, leading us to investigate mechanisms engaged by the GLP-1RA liraglutide to increa
Externí odkaz:
https://doaj.org/article/d72c33cca2fa47dca8da218c427827be
Autor:
Michelle B. Bales, Samuel W. Centanni, Joseph R. Luchsinger, Payam Fathi, Jessica E. Biddinger, Thao D.V. Le, Kaitlyn Ginika Nwaba, Isabella M. Paldrmic, Danny G. Winder, Julio E. Ayala
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101571- (2022)
Objective: While stress typically reduces caloric intake (hypophagia) in chow-fed rodents, presentation of palatable, high calorie substances during stress can increase caloric consumption (i.e. “comfort feeding”) and promote obesity. However, li
Externí odkaz:
https://doaj.org/article/e53dbbe9d836469f9f3def19f77dc2f4
Autor:
Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggestin
Externí odkaz:
https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b496
Autor:
Robert A. Anders, Sepideh Besharati, Xinqun Wu, Franck Housseau, Payam Fathi, Jawara Allen, Laura Jenkins, Shaoguang Wu, David L. Huso, Amanda E. Mackenzie, Ben Park, Cynthia L. Sears, Graeme Milligan, Annemarie Boleij, William Brian Dalton
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, 4
Communications Biology
Communications Biology, 4, 1
Communications Biology, 4
Communications Biology
Communications Biology, 4, 1
G protein-coupled receptor (GPR)35 is highly expressed in the gastro-intestinal tract, predominantly in colon epithelial cells (CEC), and has been associated with inflammatory bowel diseases (IBD), suggesting a role in gastrointestinal inflammation.
Autor:
Ye Yang, Raad Z. Gharaibeh, Payam Fathi, Shaoguang Wu, Liam Chung, Anthony A. Fodor, Sarah Tomkovich, Sepideh Besharati, Marcus Mühlbauer, James R. White, Jillian L. Pope, Cynthia L. Sears, Ernesto Perez-Chanona, Drew M. Pardoll, Julia L. Drewes, Kathryn Winglee, Xinqun Wu, Robert A. Anders, Christian Jobin, Franck Housseau, Christine M. Dejea, Hao Wang, Xiaolun Sun, Josee Gauthier, Xiuli Liu, Hua Ding
Publikováno v:
Journal of Clinical Investigation. 129:1699-1712
Mucus-invasive bacterial biofilms are identified on the colon mucosa of approximately 50% of colorectal cancer (CRC) patients and approximately 13% of healthy subjects. Here, we test the hypothesis that human colon biofilms comprise microbial communi
Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Autor:
John M. Craig, Shaoguang Wu, Christina E. DeStefano Shields, Xinqun Wu, Robert A. Anders, Christine M. Dejea, Rahwa Taddese, Hao Wang, Abby L. Geis, David L. Huso, Drew M. Pardoll, Francis M. Giardiello, Elizabeth C. Wick, Annemarie Boleij, Franck Housseau, Payam Fathi, Elizabeth M. Hechenbleikner, Cynthia L. Sears
Publikováno v:
Science, 359, 6375, pp. 592-597
Science, 359, 592-597
Science, 359, 592-597
Biofilms provide refuge for cancerous bacteria Familial adenomatous polyposis (FAP) causes benign polyps along the colon. If left untreated, FAP leads to a high incidence of colon cancer. To understand how polyps influence tumor formation, Dejea et a
Autor:
Elizabeth C. Wick, Jane W. Wanyiri, Han Ming Gan, Kumar Thulasi, Cynthia L. Sears, Hoong Yin Chong, April Camilla Roslani, Emmanuel F. Mongodin, Julia L. Drewes, Khean-Lee Goh, Jamuna Vadivelu, James R. White, Mun Fai Loke, Payam Fathi, Thevambiga Iyadorai, Christine M. Dejea, Sandip Kumar
Publikováno v:
npj Biofilms and Microbiomes, Vol 5, Iss 1, Pp 1-1 (2019)
NPJ Biofilms and Microbiomes
NPJ Biofilms and Microbiomes
In this Article, in the section entitled ‘Quantitative real-time PCR’ within the Supplementary Methods, the probe for the Bacteroides fragilis 16S real-time PCR reaction was listed incorrectly as 5ʹHEX-AGGGACTGGAAGGCTTTACTGCTTC-3ʹBHQ1. The corr
Autor:
Shaoguang Wu, Payam Fathi
Publikováno v:
The Open Microbiology Journal
Bacteroides fragilisis an extensively studied anaerobic bacterium comprising the normal flora of the human gut.B. fragilisis known to be one of the most commonly isolated species from clinical samples and has been shown to cause a wide range of patho
Autor:
Jessica, Mavadia-Shukla, Payam, Fathi, Wenxuan, Liang, Shaoguang, Wu, Cynthia, Sears, Xingde, Li
Publikováno v:
Biomedical optics express. 9(8)
We present the first, most compact, ultrahigh-resolution, high-speed, distal scanning optical coherence tomography (OCT) endoscope operating at 800 nm. Achieving high speed imaging while maintaining an ultrahigh axial resolution is one of the most si
Autor:
Fengyi Wan, Paul Metz, Sudipto Ganguly, Drew M. Pardoll, Hongni Fan, Christina E. DeStefano Shields, David L. Huso, Florencia McAllister, Kai Fu, Shaoguang Wu, Benjamin B. Finard, June Chan, Payam Fathi, Jie Chen, Ada J. Tam, Cynthia L. Sears, Franck Housseau, Christine M. Dejea, Abby L. Geis, Elizabeth C. Wick, Sara W. Van Meerbeke, Liam Chung, Erik Thiele-Orberg, Xinqun Wu
Publikováno v:
SSRN Electronic Journal.
Pro-carcinogenic bacteria have the potential to initiate and/or promote human colon cancer. However, the mechanism(s) by which a bacterium may trigger carcinogenesis remains unclear. Herein, we show Bacteroides fragilis toxin (BFT) secretion by the h