Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Payal Sheth"'
Autor:
Scott S Walker, Marc Labroli, Ronald E Painter, Judyann Wiltsie, Brad Sherborne, Nicholas Murgolo, Xinwei Sher, Paul Mann, Paul Zuck, Charles G Garlisi, Jing Su, Stacia Kargman, Li Xiao, Giovanna Scapin, Scott Salowe, Kristine Devito, Payal Sheth, Nichole Buist, Christopher M Tan, Todd A Black, Terry Roemer
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180965 (2017)
To combat the threat of antibiotic-resistant Gram-negative bacteria, novel agents that circumvent established resistance mechanisms are urgently needed. Our approach was to focus first on identifying bioactive small molecules followed by chemical lea
Externí odkaz:
https://doaj.org/article/d07ac785ed0e484b8e91ce784204be8a
Autor:
Mihirbaran Mandal, Li Xiao, Weidong Pan, Giovanna Scapin, Guoqing Li, Haiqun Tang, Shu-Wei Yang, Jianping Pan, Yuriko Root, Reynalda Keh de Jesus, Christine Yang, Winnie Prosise, Priya Dayananth, Asra Mirza, Alex G. Therien, Katherine Young, Amy Flattery, Charles Garlisi, Rumin Zhang, Donald Chu, Payal Sheth, Inhou Chu, Jin Wu, Carrie Markgraf, Hai-Young Kim, Ronald Painter, Todd W. Mayhood, Edward DiNunzio, Daniel F. Wyss, Alexei V. Buevich, Thierry Fischmann, Alexander Pasternak, Shuzhi Dong, Jacqueline D. Hicks, Artjohn Villafania, Lianzhu Liang, Nicholas Murgolo, Todd Black, William K. Hagmann, Jim Tata, Emma R. Parmee, Ann E. Weber, Jing Su, Haifeng Tang
Publikováno v:
Journal of Medicinal Chemistry. 65:16234-16251
With the emergence and rapid spreading of NDM-1 and existence of clinically relevant VIM-1 and IMP-1, discovery of pan inhibitors targeting metallo-beta-lactamases (MBLs) became critical in our battle against bacterial infection. Concurrent with our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72a226d0f459e4620537979c8da4d4d
https://doi.org/10.1021/acs.jmedchem.2c00766
https://doi.org/10.1021/acs.jmedchem.2c00766
Autor:
Carl J. Balibar, Daniel J. Klein, Beata Zamlynny, Tracy L. Diamond, Zhiyu Fang, Carol A. Cheney, Jan Kristoff, Meiqing Lu, Marina Bukhtiyarova, Yangsi Ou, Min Xu, Lei Ba, Steven S. Carroll, Abdellatif El Marrouni, John F. Fay, Ashley Forster, Shih Lin Goh, Meigang Gu, Daniel Krosky, Daniel I. S. Rosenbloom, Payal Sheth, Deping Wang, Guoxin Wu, Matthias Zebisch, Tian Zhao, Paul Zuck, Jay Grobler, Daria J. Hazuda, Bonnie J. Howell, Antonella Converso
Publikováno v:
Science Translational Medicine. 15
Antiretroviral therapy inhibits HIV-1 replication but is not curative due to establishment of a persistent reservoir after virus integration into the host genome. Reservoir reduction is therefore an important HIV-1 cure strategy. Some HIV-1 nonnucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512a144edadcb09a3ad7b6560f3b8bab
https://doi.org/10.1126/scitranslmed.abn2038
https://doi.org/10.1126/scitranslmed.abn2038
Autor:
Paul Tawa, Lei Zhang, Essam Metwally, Yan Hou, Mark A. McCoy, W. Michael Seganish, Rumin Zhang, Emily Frank, Payal Sheth, Jennifer Hanisak, Christopher Sondey, David Bauman, Aileen Soriano
Publikováno v:
The Journal of biological chemistry. 298(9)
cGMP-dependent protein kinase (PKG) represents a compelling drug target for treatment of cardiovascular diseases. PKG1 is the major effector of beneficial cGMP signaling which is involved in smooth muscle relaxation and vascular tone, inhibition of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c725ecfa9c2f786568a217b32fbd8e
https://pubmed.ncbi.nlm.nih.gov/35868561
https://pubmed.ncbi.nlm.nih.gov/35868561