DNA methylation-based classification of sinonasal tumors.

Autor: Jurmeister P; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Munich, Germany. philipp.jurmeister@med.uni-muenchen.de.; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany. philipp.jurmeister@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany. philipp.jurmeister@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner Site Munich, and German Cancer Research Center (DKFZ), Heidelberg, Germany. philipp.jurmeister@med.uni-muenchen.de., Glöß S; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany., Roller R; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Proteomics Platform, Berlin Institute of Health (BIH) and Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125, Berlin, Germany., Leitheiser M; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Schmid S; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany., Mochmann LH; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Munich, Germany., Payá Capilla E; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Munich, Germany., Fritz R; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Dittmayer C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany., Friedrich C; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; MDC Graduate School, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; Humboldt Universität zu Berlin, Institute of Chemistry, Berlin, Germany., Thieme A; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany., Keyl P; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Jarosch A; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Schallenberg S; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Bläker H; Institute of Pathology, University Hospital Leipzig, Leipzig, Germany., Hoffmann I; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Vollbrecht C; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Lehmann A; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Hummel M; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany., Heim D; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Haji M; Proteomics Platform, Berlin Institute of Health (BIH) and Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125, Berlin, Germany., Harter P; German Cancer Consortium (DKTK), Partner Site Munich, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ), Heidelberg, Germany., Englert B; Institute of Neuropathology, Ludwig Maximilians University Hospital Munich, Munich, Germany., Frank S; Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland., Hench J; Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland., Paulus W; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Hasselblatt M; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Hartmann W; Division of Translational Pathology, Gerhard-Domagk-Institute of Pathology, University Hospital Münster, Münster, Germany., Dohmen H; Institute of Neuropathology, University of Giessen, Giessen, Germany., Keber U; Institute of Neuropathology, Philipps-University, Marburg, Germany., Jank P; Institute of Pathology, Philipps-University Marburg and University Hospital Marburg, Marburg, Germany., Denkert C; Institute of Pathology, Philipps-University Marburg and University Hospital Marburg, Marburg, Germany., Stadelmann C; Institute for Neuropathology, University Medical Centre Göttingen, Göttingen, Germany., Bremmer F; Institute of Pathology, University Medical Center, Göttingen, Germany., Richter A; Institute of Pathology, University Medical Center, Göttingen, Germany., Wefers A; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ribbat-Idel J; Institute of Pathology, University of Luebeck and University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany., Perner S; Institute of Pathology, University of Luebeck and University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.; Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.; German Center for Lung Research (DZL), Partner Site Luebeck, Luebeck, Germany., Idel C; Department of Otorhinolaryngology, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany., Chiariotti L; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Via S. Pansini 5, 80131, Naples, Italy.; CEINGE Biotecnologie Avanzate, 80145, Naples, Italy., Della Monica R; CEINGE Biotecnologie Avanzate, 80145, Naples, Italy., Marinelli A; Department of Medicina Clinica e Chirurgia, University Federico II, Naples, Italy., Schüller U; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center Hamburg, Hamburg, Germany., Bockmayr M; Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Institute Children's Cancer Center Hamburg, Hamburg, Germany., Liu J; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT, UK.; UCL Academic Head and Neck Centre, Division of Surgery and Interventional Science, University College London, London, UK., Lund VJ; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT, UK.; UCL Academic Head and Neck Centre, Division of Surgery and Interventional Science, University College London, London, UK., Forster M; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT, UK.; UCL Academic Head and Neck Centre, Division of Surgery and Interventional Science, University College London, London, UK., Lechner M; UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT, UK.; UCL Academic Head and Neck Centre, Division of Surgery and Interventional Science, University College London, London, UK., Lorenzo-Guerra SL; Department of Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain., Hermsen M; Department of Head and Neck Oncology, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain., Johann PD; Swabian Childrens' Cancer Center, University Childrens' Hospital Augsburg and EU-RHAB Registry, Augsburg, Germany., Agaimy A; Institute of Pathology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital, Erlangen, Germany., Seegerer P; Machine-Learning Group, Department of Software Engineering and Theoretical Computer Science, Technical University of Berlin, Berlin, Germany., Koch A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany., Heppner F; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany., Pfister SM; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Jones DTW; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Glioma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sill M; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany., von Deimling A; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Snuderl M; Division of Neuropathology, NYU Langone Health, New York, USA.; Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, USA.; Division of Molecular Pathology and Diagnostics, NYU Langone Health, New York, USA., Müller KR; Machine-Learning Group, Department of Software Engineering and Theoretical Computer Science, Technical University of Berlin, Berlin, Germany.; Department of Artificial Intelligence, Korea University, Seoul, South Korea.; Max-Planck-Institute for Informatics, Saarbrücken, Germany.; BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany., Forgó E; Stanford University School of Medicine, Stanford, CA, USA., Howitt BE; Stanford University School of Medicine, Stanford, CA, USA., Mertins P; Proteomics Platform, Berlin Institute of Health (BIH) and Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125, Berlin, Germany., Klauschen F; Institute of Pathology, Ludwig Maximilians University Hospital Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; BIFOLD - Berlin Institute for the Foundations of Learning and Data, Berlin, Germany., Capper D; German Cancer Consortium (DKTK), Partner Site Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, Berlin, Germany.

Publikováno v: Nature communications [Nat Commun] 2022 Nov 28; Vol. 13 (1), pp. 7148. Date of Electronic Publication: 2022 Nov 28.

EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics.

Autor: Hench, Jürgen¹ (AUTHOR) juergen.hench@usb.ch, Hultschig, Claus¹ (AUTHOR), Brugger, Jon¹ (AUTHOR), Mariani, Luigi² (AUTHOR), Guzman, Raphael² (AUTHOR), Soleman, Jehuda² (AUTHOR), Leu, Severina² (AUTHOR), Benton, Miles³ (AUTHOR), Stec, Irenäus Maria¹ (AUTHOR), Hench, Ivana Bratic¹ (AUTHOR), Hoffmann, Per⁴ (AUTHOR), Harter, Patrick⁵ (AUTHOR), Weber, Katharina J^6,7,8 (AUTHOR), Albers, Anne⁹ (AUTHOR), Thomas, Christian⁹ (AUTHOR), Hasselblatt, Martin⁹ (AUTHOR), Schüller, Ulrich^10,11,12,13 (AUTHOR), Restelli, Lisa¹ (AUTHOR), Capper, David¹⁴ (AUTHOR), Hewer, Ekkehard¹⁵ (AUTHOR)

Publikováno v: Acta Neuropathologica Communications. 4/4/2024, Vol. 12 Issue 1, p1-16. 16p.

Sinonasal Cancer: Improving Classification, Stratification and Therapeutic Options.

Autor: Hermsen, Mario A.¹ (AUTHOR) mhermsen@hca.es, Bossi, Paolo² (AUTHOR), Franchi, Alessandro³ (AUTHOR), Lechner, Matt^4,5 (AUTHOR) mhermsen@hca.es

Publikováno v: Cancers. Mar2023, Vol. 15 Issue 6, p1675. 6p.

Resveratrol ameliorates ulcerative colitis by upregulating Nrf2/HO‑1 pathway activity: Integrating animal experiments and network pharmacology.

Autor: Yu, Xinya¹ (AUTHOR), Li, Xiaoxi² (AUTHOR), Xu, Yunchun¹ (AUTHOR), Li, Yuwei¹ (AUTHOR), Zhou, Ye¹ (AUTHOR), Zhang, Junhua² (AUTHOR), Guo, Le¹ (AUTHOR) nanshengcheng@yeah.net

Publikováno v: Molecular Medicine Reports. May2024, Vol. 29 Issue 5, pN.PAG-N.PAG. 1p.