Zobrazeno 1 - 10
of 1 444
pro vyhledávání: '"Pawson, T."'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2006 Jun . 103(25), 9536-9541.
Externí odkaz:
https://www.jstor.org/stable/30050944
Autor:
Helbig, A.O., Kofler, M., Gish, G., Lorenzen, K., Tucholska, M., Zhang, C., Roth, F.P., Colwill, K., Pawson, T., Petsalaki, E.
Summary The c-Fes protein tyrosine kinase is a proto-oncogene that can also act as a tumor suppressor. We implemented a novel phosphoproteomics-based analysis that establishes cognate kinase-substrate associations, and revealed that c-Fes directly ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::2d30a8f8625009c6cc47a2ad59e9149d
Autor:
Pawson, T.1,2 pawson@mshri.on.ca, Warner, N.1,2
Publikováno v:
Oncogene. 2/26/2007, Vol. 26 Issue 9, p1268-1275. 8p. 4 Diagrams.
Autor:
Abraham, S, Scarcia, M, Bagshaw, R, McMahon, K, Grant, G, Harvey, T, Yeo, M, Esteves, FOG, Thygesen, HH, Jones, PF, Spiers, V, Hanby, AM, Selby, PJ, Lorger, M, Dear, TN, Pawson, T, Marshall, CJ, Mavria, G
Publikováno v:
Abraham, S, Scarcia, M, Bagshaw, R D, McMahon, K, Grant, G, Harvey, T, Yeo, M, Esteves, F O G, Thygesen, H H, Jones, P F, Speirs, V, Hanby, A M, Selby, P J, Lorger, M, Dear, T N, Pawson, T, Marshall, C J & Mavria, G 2015, ' A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. ', Nature Communications, vol. 6, 7286 . https://doi.org/10.1038/ncomms8286
During angiogenesis, Rho-GTPases influence endothelial cell migration and cell-cell adhesion; however it is not known whether they control formation of vessel lumens, which are essential for blood flow. Here, using an organotypic system that recapitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e5887d439b75c4b51f32ef900b66d270
https://www.research.manchester.ac.uk/portal/en/publications/a-raccdc42-exchange-factor-complex-promotes-formation-of-lateral-filopodia-and-blood-vessel-lumen-morphogenesis(76445d51-ddd6-4605-971a-2b2101e43b86).html
https://www.research.manchester.ac.uk/portal/en/publications/a-raccdc42-exchange-factor-complex-promotes-formation-of-lateral-filopodia-and-blood-vessel-lumen-morphogenesis(76445d51-ddd6-4605-971a-2b2101e43b86).html
Autor:
Gray, E.J., Petsalaki, E., James, D.A., Bagshaw, R.D., Stacey, M.M., Rocks, O., Gingras, A.C., Pawson, T.
SH2D5 is a mammalian-specific, uncharacterized adaptor-like protein that contains an N-terminal phosphotyrosine binding (PTB) domain and a C-terminal Src Homology 2 (SH2) domain. We show that SH2D5 is highly enriched in adult mouse brain, particularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=mdc______med::c5c9fd30dbd49295f7186bcd9f411d0a
http://edoc.mdc-berlin.de/14406/7/14406oa.pdf
http://edoc.mdc-berlin.de/14406/7/14406oa.pdf
Publikováno v:
Scientific American; Jun2000, Vol. 282 Issue 6, p72-79, 8p, 2 Color Photographs, 2 Diagrams
Autor:
Oak J, A. Andrew Ray, Ross G. Vickery, John Oldenhof, Pawson T, Schoots O, Van Tol Hh, Anafi M, von Zastrow M
Publikováno v:
Biochemistry. 37:15726-15736
The dopamine D4 receptor is a G protein-coupled receptor (GPCR) that belongs to the dopamine D2-like receptor family. Functionally, the D2-like receptors are characterized by their ability to inhibit adenylyl cyclase. The dopamine D4 receptor as well
Publikováno v:
Journal of Immunology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1874::ce353eddb0fb3f36ebe259bc2fab19ee
https://hdl.handle.net/11858/00-001M-0000-0014-4FDE-5
https://hdl.handle.net/11858/00-001M-0000-0014-4FDE-5
Publikováno v:
Molecular and Cellular Biology. 12:5087-5093
SH2 (src homology region 2) domains are implicated in protein-protein interactions involved in signal transduction pathways. Isolated SH2 domains bind proteins that are tyrosine phosphorylated. A novel, phosphotyrosine-independent binding interaction