Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pawel Pomorski"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 7, p e1004303 (2015)
Ion channels catalyze ionic permeation across membranes via water-filled pores. To understand how changes in intracellular magnesium concentration regulate the influx of Mg2+ into cells, we examine early events in the relaxation of Mg2+ channel CorA
Externí odkaz:
https://doaj.org/article/27f8707424024a6680df32ff0553317f
Autor:
Lukasz Michal Szafron, Anna Balcerak, Ewa Anna Grzybowska, Barbara Pienkowska-Grela, Anna Felisiak-Golabek, Agnieszka Podgorska, Magdalena Kulesza, Natalia Nowak, Pawel Pomorski, Juliusz Wysocki, Tymon Rubel, Agnieszka Dansonka-Mieszkowska, Bozena Konopka, Martyna Lukasik, Jolanta Kupryjanczyk
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127475 (2015)
CRNDE, recently described as the lncRNA-coding gene, is overexpressed at RNA level in human malignancies. Its role in gametogenesis, cellular differentiation and pluripotency has been suggested as well. Herein, we aimed to verify our hypothesis that
Externí odkaz:
https://doaj.org/article/18e45ca8573242ad8f19658983ea37fc
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19285 (2011)
The interaction between Ca(2+) sensors STIM1 and STIM2 and Ca(2+) channel-forming protein ORAI1 is a crucial element of store-operated calcium entry (SOCE) in non-excitable cells. However, the molecular mechanism of SOCE in neurons remains unclear. W
Externí odkaz:
https://doaj.org/article/834bfff62e4f465e9497442e25499af2
Autor:
Patryk Krzemiński, Irena Misiewicz-Krzemińska, Marta Grodzik, Irena Padzińska-Pruszyńska, Paulina Kucharzewska, Agnieszka Ostrowska, Ewa Sawosz, Paweł Pomorski
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116090- (2024)
Purpose: The aim of the study was to evaluate the effect of silver nanoparticles hydrocolloids (AgNPs) on human corneal epithelial cells. Epithelial cells form the outermost and the most vulnerable to environmental stimuli layer of the cornea in the
Externí odkaz:
https://doaj.org/article/dd9191428b9c42e5984bb77a7502620e
Autor:
Pekka T. Männistö, Alex Bunker, Pawel Pomorski, Mikko Karttunen, Lorna M. Stimson, J.-F. St. Pierre, Tomasz Róg
Publikováno v:
SAR and QSAR in Environmental Research, 19(1-2), 179-189. Taylor and Francis Ltd.
Presented at CMTPI 2007: Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (Moscow, Russia, September 1–5, 2007). Results from extensive 70 ns all-atom molecular dynamics simulations of catechol-O-methyltransferase
Publikováno v:
The Journal of Chemical Physics. 120:4530-4544
It has long been known that accurate electrostatics is a key issue for improving current force fields for large-scale biomolecular simulations. Typically, this calls for an improved and more accurate description of the molecular electrostatic potenti
Publikováno v:
Cell Motility and the Cytoskeleton. 57:143-157
We investigated the mechanisms by which primary human monocyte migration and the production of important cytokines are co-regulated. Motile monocytes underwent cyclic morphologic and adhesive changes that were associated with intracellular free calci
Publikováno v:
Nature Cell Biology. 4:E91-E96
Modern light microscopy has evolved to provide a variety of quantitative imaging techniques and also the capability to perturb structure-function relationships in living cells. The advances have been especially useful in the study of cell adhesion an
Autor:
Pawel Pomorski, Olga Pletjushkina, Zenon Rajfur, Timothy N. Oliver, Ken Jacobson, J M Vasiliev
Publikováno v:
Cell Motility and the Cytoskeleton. 48:235-244
Actomyosin-based cortical contractility is a common feature of eukaryotic cells but the capability to produce rhythmic contractions is found in only a few types such as cardiomyocytes. Mechanisms responsible for the acquisition of this capability rem
Publikováno v:
Biochemistry and Cell Biology. 78:487-494
Micrurgically isolated interphasal nuclei of Amoeba proteus, which preserve F-actin cytoskeletal shells on their surface, shrink after perfusion with imidazole buffer without ATP, and expand to about 200% of their cross-sectional area upon addition o