Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Pawel Mroz"'
Autor:
Ramzi G. Salloum, Jeffrey R. Bishop, Amanda L. Elchynski, D. Max Smith, Elizabeth Rowe, Kathryn V. Blake, Nita A. Limdi, Christina L. Aquilante, Jill Bates, Amber L. Beitelshees, Amber Cipriani, Benjamin Q. Duong, Philip E. Empey, Christine M. Formea, J. Kevin Hicks, Pawel Mroz, David Oslin, Amy L. Pasternak, Natasha Petry, Laura B. Ramsey, Allyson Schlichte, Sandra M. Swain, Kristen M. Ward, Kristin Wiisanen, Todd C. Skaar, Sara L. Van Driest, Larisa H. Cavallari, Sony Tuteja
Publikováno v:
Implementation Science Communications, Vol 3, Iss 1, Pp 1-9 (2022)
Abstract Background Despite the increased demand for pharmacogenetic (PGx) testing to guide antidepressant use, little is known about how to implement testing in clinical practice. Best–worst scaling (BWS) is a stated preferences technique for dete
Externí odkaz:
https://doaj.org/article/622e160da30149b7bb83516b31e629d0
Autor:
Sony Tuteja, Ramzi G. Salloum, Amanda L. Elchynski, D. Max Smith, Elizabeth Rowe, Kathryn V. Blake, Nita A. Limdi, Christina L. Aquilante, Jill Bates, Amber L. Beitelshees, Amber Cipriani, Benjamin Q. Duong, Philip E. Empey, Christine M. Formea, J. Kevin Hicks, Pawel Mroz, David Oslin, Amy L. Pasternak, Natasha Petry, Laura B. Ramsey, Allyson Schlichte, Sandra M. Swain, Kristen M. Ward, Kristin Wiisanen, Todd C. Skaar, Sara L. Van Driest, Larisa H. Cavallari, Jeffrey R. Bishop, for the IGNITE Pharmacogenetics Working Group
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 2, Pp 371-383 (2022)
Abstract There is growing interest in utilizing pharmacogenetic (PGx) testing to guide antidepressant use, but there is lack of clarity on how to implement testing into clinical practice. We administered two surveys at 17 sites that had implemented o
Externí odkaz:
https://doaj.org/article/8db7d4a68b104a13ba4ac33d91a1855f
Autor:
Pawel Mroz, Stephen Michel, Josiah D. Allen, Tim Meyer, Erin J. McGonagle, Rachel Carpentier, Alexandra Vecchia, Allyson Schlichte, Jeffrey R. Bishop, Henry M. Dunnenberger, Sophia Yohe, Bharat Thyagarajan, Pamala A. Jacobson, Steven G. Johnson
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Pharmacogenomics (PGx) studies how a person’s genes affect the response to medications and is quickly becoming a significant part of precision medicine. The clinical application of PGx principles has consistently been cited as a major opportunity f
Externí odkaz:
https://doaj.org/article/59b49c07f0c5493f970fbf3b9e253911
Autor:
Paige Hartman, Kenneth Beckman, Kevin Silverstein, Sophia Yohe, Matthew Schomaker, Christine Henzler, Getiria Onsongo, Ham Ching Lam, Sarah Munro, Jerry Daniel, Bradley Billstein, Archana Deshpande, Adam Hauge, Pawel Mroz, Whiwon Lee, Jennifer Holle, Katie Wiens, Kylene Karnuth, Teresa Kemmer, Michaela Leary, Stephen Michel, Laurie Pohlman, Venugopal Thayanithy, Andrew Nelson, Matthew Bower, Bharat Thyagarajan
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 19, Iss , Pp - (2019)
Clinical laboratories have adopted next generation sequencing (NGS) as a gold standard for the diagnosis of hereditary disorders because of its analytic accuracy, high throughput, and potential for cost-effectiveness. We describe the implementation o
Externí odkaz:
https://doaj.org/article/7f786e4d73364fba9230596203bd40b1
Publikováno v:
Case Reports in Hematology, Vol 2019 (2019)
Pure white cell aplasia (PWCA) is a rare manifestation of thymoma. It is characterized by agranulocytosis with absent myeloid precursors in the bone marrow and normal hematopoiesis for other cell lines. Here we describe a 65-year-old female patient w
Externí odkaz:
https://doaj.org/article/d1ea493d0efe483c8ccfa1c9d344f80b
Autor:
Masamitsu Tanaka, Pawel Mroz, Tianhong Dai, Liyi Huang, Yuji Morimoto, Manabu Kinoshita, Yasuo Yoshihara, Koichi Nemoto, Nariyoshi Shinomiya, Suhji Seki, Michael R Hamblin
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39823 (2012)
Local microbial infections induced by multiple-drug-resistant bacteria in the orthopedic field can be intractable, therefore development of new therapeutic modalities is needed. Photodynamic therapy (PDT) is a promising alternative modality to antibi
Externí odkaz:
https://doaj.org/article/9c55132c0d104ecf8b7d4f9327655771
Photodynamic therapy of tumors can lead to development of systemic antigen-specific immune response.
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15194 (2010)
The mechanism by which the immune system can effectively recognize and destroy tumors is dependent on recognition of tumor antigens. The molecular identity of a number of these antigens has recently been identified and several immunotherapies have ex
Externí odkaz:
https://doaj.org/article/d420a3f031554e54850935c868575cb8
Autor:
Thomas D. Lee, Dara L. Aisner, Marjorie Parker David, Celeste C. Eno, Jeffrey Gagan, Christopher D. Gocke, Natalya V. Guseva, Lisa Haley, Audrey N. Jajosky, Daniel Jones, Mahesh M. Mansukhani, Pawel Mroz, Sarah S. Murray, Kimberly J. Newsom, Vera Ashley Paulson, Somak Roy, Chase Rushton, Jeremy P. Segal, T. Niroshini Senaratne, Alexa J. Siddon, Petr Starostik, Jessica A. G. Van Ziffle, David Wu, Rena R. Xian, Sophia Yohe, Annette S. Kim
Publikováno v:
Blood Advances.
While molecular testing of hematologic malignancies is now standard of care, there is variability in practice and testing capabilities between different academic laboratories, with common questions arising on how to best meet clinical expectations. A
Autor:
Joel F. Farley, David D. Stenehjem, Susan M. Wolf, Josiah D Allen, Constantin F. Aliferis, Erin J McGonagle, Steven G. Johnson, Robert J. Straka, Jason Wachtl, Catherine A. McCarty, Christine Kroger, Pinar Karaca Mandic, Pamala A. Pawloski, Allyson Schlichte, Julie England, Susie E Long, Heather Zierhut, Pamala A. Jacobson, Wayne T. Nicholson, Eric T. Matey, Sisi Ma, Stephen W. Schondelmeyer, Tiana Luczak, Suzette J. Bielinski, Pawel Mroz, Jacob T. Brown, Jeffrey R. Bishop, Jyothsna Giri, David Gregornik, Stephen C. Waring, Natasha Petry, R. Stephanie Huang, Ann M. Moyer, Marilyn K. Speedie, Randall D. Seifert, Brian G Van Ness
Publikováno v:
Pharmacogenomics
Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increase drug safety and effectiveness. Healthcare professional and student education is strong and there are multiple opportunities in
Autor:
Siddhartha Sen, Anna Pratt, Susan Harley, Pawel Mroz, Sophia Yohe, Bharat Thyagarajan, Matthew Schomaker, Robyn Kincaid, Stephen Michel, Faqian Li
Publikováno v:
American Journal of Clinical Pathology. 158:S21-S22
Background PD1/PDL1 inhibitors have significantly improved overall survival in non-small cell lung cancer (NSCLC). PDL1 is now a standard biomarker along with molecular testing for therapy selection. Checkpoint therapy is given front-line for patient