Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Pawel Licznerski"'
Autor:
Han-A Park, Nelli Mnatsakanyan, Katheryn Broman, Abigail U. Davis, Jordan May, Pawel Licznerski, Kristi M. Crowe-White, Kimberly H. Lackey, Elizabeth A. Jonas
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 220 (2019)
B-cell lymphoma-extra large (Bcl-xL) is an anti-apoptotic member of the Bcl2 family of proteins, which supports neurite outgrowth and neurotransmission by improving mitochondrial function. During excitotoxic stimulation, however, Bcl-xL undergoes pos
Externí odkaz:
https://doaj.org/article/c7626309189346bdb240f3db89084ca7
Autor:
Pawel Licznerski, Vanja Duric, Mounira Banasr, Kambiz N Alavian, Kristie T Ota, Hyo Jung Kang, Elizabeth A Jonas, Robert Ursano, John H Krystal, Ronald S Duman, Traumatic Stress Brain Study Group
Publikováno v:
PLoS Biology, Vol 13, Iss 10, p e1002282 (2015)
Exposure to extreme stress can trigger the development of major depressive disorder (MDD) as well as post-traumatic stress disorder (PTSD). The molecular mechanisms underlying the structural and functional alterations within corticolimbic brain regio
Externí odkaz:
https://doaj.org/article/80f1f1c285684de08991174b81c6301c
Autor:
Sebastian Haesler, Christelle Rochefort, Benjamin Georgi, Pawel Licznerski, Pavel Osten, Constance Scharff
Publikováno v:
PLoS Biology, Vol 5, Iss 12, p e321 (2007)
The gene encoding the forkhead box transcription factor, FOXP2, is essential for developing the full articulatory power of human language. Mutations of FOXP2 cause developmental verbal dyspraxia (DVD), a speech and language disorder that compromises
Externí odkaz:
https://doaj.org/article/b9060776d29b4da9845373e02fd69674
Autor:
Tansu Celikel, Verena Marx, Florian Freudenberg, Aleksander Zivkovic, Evgeny Resnik, Mazahir T Hasan, Pawel Licznerski, Pavel Osten, Andrej Rozov, Peter H Seeburg, Martin K Schwarz
Publikováno v:
Frontiers in Neuroscience, Vol 1 (2007)
Long Homer proteins forge assemblies of signaling components involved in glutamate receptor signaling in postsynaptic excitatory neurons, including those underlying synaptic transmission and plasticity. The short immediate-early gene (IEG) Homer1a ca
Externí odkaz:
https://doaj.org/article/48b3ef34f7d347cfb88c385cc58eafaf
Autor:
Han-A Park, Kristi M. Crowe-White, Lukasz Ciesla, Madison Scott, Sydni Bannerman, Abigail U. Davis, Bishnu Adhikari, Garrett Burnett, Katheryn Broman, Khondoker Adeba Ferdous, Kimberly H. Lackey, Pawel Licznerski, Elizabeth A. Jonas
Publikováno v:
Nutr Res
Alpha-tocotrienol (α-TCT) is a member of the vitamin E family. It has been reported to protect the brain against various pathologies including cerebral ischemia and neurodegeneration. However, it is still unclear if α-TCT exhibits beneficial effect
Autor:
Linlin Sun, Catarina M. Quinzii, Matthew Tracey, Elizabeth A. Jonas, Jose F. Perez-Zoghbi, Pawel Licznerski, Giulio Kleiner, Aili Wang, Richard J. Levy, Mu Yang, Lifei Wang, Guang Yang, Keren K. Griffiths
Publikováno v:
FASEB J
Fragile X syndrome (FXS) is the leading known inherited intellectual disability and the most common genetic cause of autism. The full mutation results in transcriptional silencing of the Fmr1 gene and loss of fragile X mental retardation protein (FMR
Autor:
Elizabeth A. Jonas, Han-A Park, Abigail U. Davis, Pawel Licznerski, Sydni Bannerman, Kimberly H. Lackey, Madison Scott, Katheryn Broman, Kristi Crowe-White, Garret Burnett
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Neurite outgrowth is a foundational process in brain development and recovery from brain injury. Assembly of the cytoskeleton and formation of new synapses during neurite outgrowth requires an abundance of energy. We have reported that th
Autor:
Brian M. Polster, Jing Wu, Pawel Licznerski, Kambiz N. Alavian, Han-A Park, Nelli Mnatsakanyan, Yulong Niu, Silvio Sacchetti, Elizabeth A. Jonas
Publikováno v:
Cell Death and Differentiation
ABT-737 is a pharmacological inhibitor of the anti-apoptotic activity of B-cell lymphoma-extra large (Bcl-xL) protein; it promotes apoptosis of cancer cells by occupying the BH3-binding pocket. We have shown previously that ABT-737 lowers cell metabo
Autor:
Agnita J.W. Boon, Han-A Park, Vincenzo Bonifati, Wim Mandemakers, Pawel Licznerski, Jack Tang, Nelli Mnatsakanyan, Morven Graham, Yulong Niu, Rongmin Chen, Giovanni Cossu, Jing Wu, Elizabeth A. Jonas, Peter K. Smith, Kambiz N. Alavian, Paige Miranda
Publikováno v:
Cell Death & Disease
Cell death & disease, 10:469. Nature Publishing Group
Cell Death and Disease, Vol 10, Iss 6, Pp 1-12 (2019)
BASE-Bielefeld Academic Search Engine
Cell death & disease, 10:469. Nature Publishing Group
Cell Death and Disease, Vol 10, Iss 6, Pp 1-12 (2019)
BASE-Bielefeld Academic Search Engine
Familial Parkinson’s disease (PD) protein DJ-1 mutations are linked to early onset PD. We have found that DJ-1 binds directly to the F1FO ATP synthase β subunit. DJ-1’s interaction with the β subunit decreased mitochondrial uncoupling and enhan
Autor:
Sana Sohail, Gulan N. Xu, Paige Miranda, Erin Song, Richard J. Levy, Charles Effman, Rongmin Chen, Nikita Mehta, Elizabeth A. Jonas, Harshvardhan Rolyan, Samuel Effman, Jing Wu, Pawel Licznerski, Nelli Mnatsakanyan, Han-A Park, Morven Graham, Lucas Brandao, Jorge Salcedo, Nicole Cruz-Reyes, Amber Braker, Valentin K. Gribkoff
Publikováno v:
Cell
Loss of the gene (Fmr1) encoding Fragile X mental retardation protein (FMRP) causes increased mRNA translation and aberrant synaptic development. We find neurons of the Fmr1-/y mouse have a mitochondrial inner membrane leak contributing to a "leak me