Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Pawel K. Olszewski"'
Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain
Autor:
Gregory M. Jacobson, Logan J. Voss, Anica Klockars, Steve Bird, Ivo Dimitrov, William A. Denny, Pawel K. Olszewski, James W. Sleigh, Martyn G. Harvey
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Ketamine ester analogs, SN 35210 and SN 35563, demonstrate different pharmacological profiles to ketamine in animal models. Both confer hypnosis with predictably rapid offset yet, paradoxically, SN35563 induces a prolonged anti-no
Externí odkaz:
https://doaj.org/article/033877a567014ff99fba432bb15ee9dd
Autor:
Michael J. Williams, Ahmed M. Alsehli, Sarah N. Gartner, Laura E. Clemensson, Sifang Liao, Anders Eriksson, Kiriana Isgrove, Lina Thelander, Zaid Khan, Pavel M. Itskov, Thiago C. Moulin, Valerie Ambrosi, Mohamed H. Al-Sabri, Francisco Alejandro Lagunas-Rangel, Pawel K. Olszewski, Helgi B. Schiöth
Publikováno v:
Cells, Vol 11, Iss 6, p 970 (2022)
The statin drug target, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), is strongly linked to body mass index (BMI), yet how HMGCR influences BMI is not understood. In mammals, studies of peripheral HMGCR have not clearly identified a role in BMI m
Externí odkaz:
https://doaj.org/article/d2ee4887765548f0a390a01cd09f5417
Autor:
David C. Jewett, Donisha S. N. K. Liyanagamage, Mark A. Vanden Avond, Molly A. B. Anderson, Kyleigh A. Twaroski, Morgan A. Marek, Kimberly F. James, Tapasya Pal, Anica Klockars, Pawel K. Olszewski, Allen S. Levine
Publikováno v:
Nutrients, Vol 14, Iss 5, p 926 (2022)
The opioid antagonist naltrexone (NTX) decreases intake of preferred diets in rats at very low doses relative to doses needed to decrease intake of “bland” laboratory chow. In the absence of an opioid agonist, NTX is not discriminable using opera
Externí odkaz:
https://doaj.org/article/474469e510904169ab664e676534d028
Autor:
Erin L. Wood, Sarah N. Gartner, Anica Klockars, Laura K. McColl, David G. Christian, Robin E. Jervis, Colin G. Prosser, Elizabeth A. Carpenter, Pawel K. Olszewski
Publikováno v:
Foods, Vol 11, Iss 2, p 141 (2022)
The natural 20:80 whey:casein ratio in cow’s milk (CM) for adults and infants is adjusted to reflect the 60:40 ratio of human milk, but the feeding and metabolic consequences of this adjustment have been understudied. In adult human subjects, the 6
Externí odkaz:
https://doaj.org/article/5d036ffa37f545c8b569f3410cd10d73
Autor:
Ali H. Al-Hamad, Aljohara M. Al-Naseeb, Maha S. Al-Assaf, Suzan A. Al-Obaid, Bandar S. Al-Abdulkarim, Pawel K. Olszewski
Publikováno v:
Nutrients, Vol 13, Iss 11, p 4156 (2021)
Background: The Children’s Eating Behaviour Questionnaire (CEBQ) is used with parents to determine the characteristics of eating behaviour of their children and, consequently, children’s propensity to become obese. It has been successfully used m
Externí odkaz:
https://doaj.org/article/6d6c3f0b13f8495d9b9c5b71fbb5a7bb
Autor:
Mitchell A. Head, David C. Jewett, Sarah N. Gartner, Anica Klockars, Allen S. Levine, Pawel K. Olszewski
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Centrally and peripherally administered oxytocin (OT) decreases food intake and activation of the endogenous OT systems, which is associated with termination of feeding. Evidence gathered thus far points to OT as a facilitator of early satiation, a p
Externí odkaz:
https://doaj.org/article/d3ab93d4a39e4d4a852f89d50d024161
Autor:
Erin L. Wood, David G. Christian, Mohammed Arafat, Laura K. McColl, Colin G. Prosser, Elizabeth A. Carpenter, Allen S. Levine, Anica Klockars, Pawel K. Olszewski
Publikováno v:
Foods, Vol 10, Iss 3, p 658 (2021)
Adjustment of protein content in milk formulations modifies protein and energy levels, ensures amino acid intake and affects satiety. The shift from the natural whey:casein ratio of ~20:80 in animal milk is oftentimes done to reflect the 60:40 ratio
Externí odkaz:
https://doaj.org/article/e3481e81d8b445709aa273c03ec8776d
Autor:
Anica Klockars, Erin L. Wood, Sarah N. Gartner, Laura K. McColl, Allen S. Levine, Elizabeth A. Carpenter, Colin G. Prosser, Pawel K. Olszewski
Publikováno v:
Nutrients, Vol 11, Iss 4, p 720 (2019)
Goat’s (GM) and cow’s milk (CM) are dietary alternatives with select health benefits shown in human and animal studies. Surprisingly, no systematic analysis of palatability or preference for GM vs. CM has been performed to date. Here, we present
Externí odkaz:
https://doaj.org/article/e847cffe160047b6ad7f0994c863a295
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 59, p 59 (2022)
Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 59
Journal of Clinical Medicine
Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 59
Journal of Clinical Medicine
A recent case report has shown that an adjunctive oxytocin + naltrexone (OT + NTX) treatment promoted more robust hypophagia and body weight reduction than OT alone in an adolescent male with hypothalamic obesity after craniopharyngioma resection. Th
Autor:
Schiöth, Michael J. Williams, Ahmed M. Alsehli, Sarah N. Gartner, Laura E. Clemensson, Sifang Liao, Anders Eriksson, Kiriana Isgrove, Lina Thelander, Zaid Khan, Pavel M. Itskov, Thiago C. Moulin, Valerie Ambrosi, Mohamed H. Al-Sabri, Francisco Alejandro Lagunas-Rangel, Pawel K. Olszewski, Helgi B.
Publikováno v:
Cells; Volume 11; Issue 6; Pages: 970
The statin drug target, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), is strongly linked to body mass index (BMI), yet how HMGCR influences BMI is not understood. In mammals, studies of peripheral HMGCR have not clearly identified a role in BMI m