Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pawel Fludzinski"'
Publikováno v:
Tetrahedron Letters. 36:7607-7610
A total synthesis of rac-patchouli alcohol (1) was achieved in six steps starting from 2,2,6-trimethylcyclohexadiene (2) using a vinyl radical cyclization strategy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d509d522713d8996cd9c7772d79c26ac
https://doi.org/10.1016/0040-4039(95)01634-t
https://doi.org/10.1016/0040-4039(95)01634-t
Publikováno v:
ChemInform. 27
A total synthesis of rac-patchouli alcohol (1) was achieved in six steps starting from 2,2,6-trimethylcyclohexadiene (2) using a vinyl radical cyclization strategy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d1b1eeabd96446b7fe7c132660be52d
https://doi.org/10.1002/chin.199605214
https://doi.org/10.1002/chin.199605214
Autor:
Pawel Fludzinski, Andrew S. Kende
Publikováno v:
Organic Syntheses
Dichlorovinylation of an enolate: 8-Ethynyl-8-methyl-1,4-dioxaspiro[4.5]dec-6-ene byproduct: 6-[(E)-1,2-dichlorovinyl]-3-ethoxy-6-methyl-2-cyclohexen-1-one intermediate: 4-[(E)-1,2-dichlorovinyl]-4-methyl-2-cyclohexen-1-one product: 8-[(E)-1,2-dichlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb09c3923bd243e130eba9d5757255bb
https://doi.org/10.1002/0471264180.os064.11
https://doi.org/10.1002/0471264180.os064.11
Autor:
Pawel Fludzinski, Andrew S. Kende
Publikováno v:
Organic Syntheses
The Stork–Danheiser kinetic alkylation procedure: 3-Ethoxy-6-methyl-2-cyclohexen-1-one product: 3-ethoxy-6-methyl-2-cyclohexen-1-one Keywords: alkylation, C-alkylation; diisopropylamine; lithium diisopropylamide (LDA), preparation of; tetrahydrofur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99bbc212b3ad34eafc4d5e830c5164d
https://doi.org/10.1002/0471264180.os064.10
https://doi.org/10.1002/0471264180.os064.10
Autor:
Andrew S. Kende, Pawel Fludzinski
Publikováno v:
Organic Syntheses
Ethyl 4-hydroxycrotonate product: ethyl 4-hydroxycrotonate Keywords: reduction, CO2H CH2OH; tetrahydrofuran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959c7b4af9dde851ddf30d15e94da344
https://doi.org/10.1002/0471264180.os064.16
https://doi.org/10.1002/0471264180.os064.16
Autor:
Pawel Fludzinski
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
(X = Cl) [1483-82-5] C8H5Cl (MW 136.57) InChI = 1S/C8H5Cl/c9-7-6-8-4-2-1-3-5-8/h1-5H InChIKey = GDWZLADUGAKASM-UHFFFAOYSA-N (X = Br) [932-87-6] C8H5Br (MW 181.03) InChI = 1S/C8H5Br/c9-7-6-8-4-2-1-3-5-8/h1-5H InChIKey = BPVHWNVBBDHIQU-UHFFFAOYSA-N (X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a020bff529ecaf1eb3fb3e8102778e2
https://doi.org/10.1002/047084289x.rc142
https://doi.org/10.1002/047084289x.rc142
Autor:
David L. Nelson, Kathy W. Schenck, Marlene L. Cohen, James E. Audia, Pawel Fludzinski, Droste James J, Gwyn R. Murdoch, Nissen Jeffrey S, Deborah Ann Evrard, Virginia L. Lucaites
Publikováno v:
Journal of medicinal chemistry. 39(14)
A series of potent, selective 5HT2B receptor antagonists has been identified based upon yohimbine, with SAR studies resulting in a 1000-fold increase in 5HT2B receptor affinity relative to the starting structure (-log KBS10.0 have been obtained). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612a97f1e71aacdf9423ceed6bec2f0a
https://pubmed.ncbi.nlm.nih.gov/8709108
https://pubmed.ncbi.nlm.nih.gov/8709108
Autor:
Jon Clardy, Pawel Fludzinski, Wendy Swenson, Michel Benechie, Andrew S. Kende, Dennis P. Curran
Publikováno v:
Tetrahedron Letters. 20:4513-4516
The condensation of certain ketone and ester enolates with trichloroethylene proceeds with surprising ease to yield dichlorovinylation products. The trans stereochemistry for one such product is established by X-ray, and subsequent transformations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a47961a8f7a4b303720740502ddc25
https://doi.org/10.1016/s0040-4039(01)86636-3
https://doi.org/10.1016/s0040-4039(01)86636-3
Publikováno v:
Journal of the American Chemical Society. 106:3551-3562
Condensation d'enolates (par exemple l'enolate de Li de la dimethyl-2,6 cyclohexene-2one) avec le trichloroethylene, d'autres ethylenes polyhalogenes et le perchlorobutadiene-1,3. Mecanisme. Lactonisation des adduits perchlorobutenyne. Condensation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a75aded2aa9318ae2fa18753895f964
https://doi.org/10.1021/ja00324a025
https://doi.org/10.1021/ja00324a025