Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pawel Bonczkowski"'
P1 Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro latency models
Autor:
Pawel Bonczkowski, Marie-Angélique De Scheerder, Eva Malatinkova, Alexandra Borch, Zora Melkova, Renate Koenig, Ward De Spiegelaere, Linos Vandekerckhove
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss , Pp 4- (2016)
Externí odkaz:
https://doaj.org/article/2541de63fff8418eb646ee65303a0e75
Autor:
Eva Malatinkova, Ward De Spiegelaere, Pawel Bonczkowski, Maja Kiselinova, Karen Vervisch, Wim Trypsteen, Margaret Johnson, Chris Verhofstede, Danny de Looze, Charles Murray, Sabine Kinloch-de Loes, Linos Vandekerckhove
Publikováno v:
eLife, Vol 4 (2015)
Persistent reservoirs remain the major obstacles to achieve an HIV-1 cure. Prolonged early antiretroviral therapy (ART) may reduce the extent of reservoirs and allow for virological control after ART discontinuation. We compared HIV-1 reservoirs in a
Externí odkaz:
https://doaj.org/article/36943e574147408383d7ca3d3e4e7a23
Autor:
Ward De Spiegelaere, Jan Philippé, Karen Vervisch, Chris Verhofstede, Eva Malatinkova, Maja Kiselinova, Wim Trypsteen, Pawel Bonczkowski, Dirk Vogelaers, Steven Callens, Jean Ruelle, Kabamba Kabeya, Stephane De Wit, Petra Van Acker, Vicky Van Sandt, Marie-Paule Emonds, Paul Coucke, Erica Sermijn, Linos Vandekerckhove
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123525 (2015)
Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 al
Externí odkaz:
https://doaj.org/article/e34e992d508a4e7ca2e338a8729d4f0b
Autor:
Camille L. Novis, Ward De Spiegelaere, Wim Trypsteen, Eva Malatinkova, Laura J. Martins, Alberto Bosque, Vicente Planelles, Adam M. Spivak, Linos Vanderkerckhove, Ana Beatriz DePaula-Silva, Pawel Bonczkowski
Publikováno v:
AIDS Research and Human Retroviruses. 32:187-193
HIV-1 latently infected cells in vivo can be found in extremely low frequencies. Therefore, in vitro cell culture models have been used extensively for the study of HIV-1 latency. Often, these in vitro systems utilize defective viruses. Defective vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb10913a836432e56645162e6d1f53d
https://doi.org/10.1089/aid.2015.0106
https://doi.org/10.1089/aid.2015.0106
Autor:
Ward De Spiegelaere, Jan De Neve, Eva Malatinkova, Olivier Thas, Wim Trypsteen, Maja Kiselinova, Linos Vandekerckhove, Matthijs Vynck, Karen Vervisch, Pawel Bonczkowski
Publikováno v:
Analytical and Bioanalytical Chemistry. 407:5827-5834
Digital PCR is rapidly gaining interest in the field of molecular biology for absolute quantification of nucleic acids. However, the first generation of platforms still needs careful validation and requires a specific methodology for data analysis to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596b6abd88811d7c8a3bf18c7c0c9fb0
https://doi.org/10.1007/s00216-015-8773-4
https://doi.org/10.1007/s00216-015-8773-4
Autor:
Renate Koenig, Ward De Spiegelaere, Eva Malatinkova, Zora Melkova, Alexandra Borch, Marie-Angélique De Scheerder, Pawel Bonczkowski, Linos Vandekerckhove
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports
To understand the persistence of latently HIV-1 infected cells in virally suppressed infected patients, a number of in vitro models of HIV latency have been developed. In an attempt to mimic the in vivo situation as closely as possible, several model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70eb8346f183adebd1b1bebf33489f66
https://doi.org/10.1038/srep38329
https://doi.org/10.1038/srep38329
Autor:
Eva Malatinkova, Karen Vervisch, Pawel Bonczkowski, Bruno Verhasselt, Wim Trypsteen, Jolien Vermeire, Maja Kiselinova, Peter Messiaen, Ward De Spiegelaere, Linos Vandekerckhove
Publikováno v:
Journal of Clinical Microbiology. 53:699-701
Episomal HIV-1 two-long terminal repeat (2-LTR) circles are considered markers for ongoing viral replication. Two sample processing procedures were compared to accurately quantify 2-LTR in patients by using droplet digital PCR (ddPCR). Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef60234c45b80e50dd6cdeefe4be121
https://doi.org/10.1128/jcm.03087-14
https://doi.org/10.1128/jcm.03087-14
P1 Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro latency models
Autor:
Ward De Spiegelaere, Zora Melkova, Eva Malatinkova, Pawel Bonczkowski, Marie-Angélique De Scheerder, Renate Koenig, Linos Vandekerckhove, Alexandra Borch
Publikováno v:
Journal of Virus Eradication, Vol 2, Iss, Pp 4-(2016)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1d24c3d3d4e2015ef85e6d1f807b9e
http://www.sciencedirect.com/science/article/pii/S2055664020310888
http://www.sciencedirect.com/science/article/pii/S2055664020310888
Autor:
Charles Murray, Chris Verhofstede, Margaret Johnson, Ward De Spiegelaere, Sabine Kinloch-de Loes, Eva Malatinkova, Wim Trypsteen, Danny De Looze, Linos Vandekerckhove, Karen Vervisch, Pawel Bonczkowski, Maja Kiselinova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a410481478e5bd5ddce6369d86c3467c
https://doi.org/10.7554/elife.09115.010
https://doi.org/10.7554/elife.09115.010
Autor:
Eva Malatinkova, Ward De Spiegelaere, Karen Vervisch, Pawel Bonczkowski, Chris Verhofstede, Steven Callens, Apostolos Beloukas, Maja Kiselinova, Wim Trypsteen, Peter Messiaen, Linos Vandekerckhove, Anna Maria Geretti
Publikováno v:
The Journal of antimicrobial chemotherapy. 70(12)
Objectives: Whether ART regimens differ in their propensity to allow persistent HIV-1 detection remains unclear. To investigate this, we performed a cross-sectional study to characterize HIV-1 persistence in peripheral blood during suppressive therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a512f99ecc4b1be32b3eb12a89493b
https://pubmed.ncbi.nlm.nih.gov/26324076
https://pubmed.ncbi.nlm.nih.gov/26324076