Selective breeding enhances coral heat tolerance to marine heatwaves

Autor: Adriana Humanes, Liam Lachs, Elizabeth Beauchamp, Leah Bukurou, Daisy Buzzoni, John Bythell, Jamie R. K. Craggs, Ruben de la Torre Cerro, Alasdair J. Edwards, Yimnang Golbuu, Helios M. Martinez, Pawel Palmowski, Eveline van der Steeg, Michael Sweet, Alex Ward, Alastair J. Wilson, James R. Guest

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Marine heatwaves are becoming more frequent, widespread and severe, causing mass coral bleaching and mortality. Natural adaptation may be insufficient to keep pace with climate warming, leading to calls for selective breeding interventions t

Externí odkaz: https://doaj.org/article/959df7285786477286d8c3ba09e8481e

Tracheostomy in children promotes persistent neutrophilic airway inflammation

Autor: Jason Powell, Steven Powell, Michael W Mather, Lauren Beck, Andrew Nelson, Pawel Palmowski, Andrew Porter, Jonathan Coxhead, Ann Hedley, Jonathan Scott, Anthony J Rostron, Thomas P Hellyer, Fatima Zaidi, Tracey Davey, James P Garnett, Rachel Agbeko, Chris Ward, Christopher J Stewart, Clifford C Taggart, Malcolm Brodlie, A John Simpson

BackgroundTracheostomies in children are associated with significant morbidity, poor quality of life, excess healthcare costs, and excess mortality. The underlying mechanisms facilitating adverse outcomes in tracheostomised children are poorly unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f26ab1a6bf8bf357244d87ef8d974c3
https://doi.org/10.1101/2022.08.17.22278448

Tracheostomy in children is associated with neutrophilic airway inflammation

Autor: Jason Powell, Steven Powell, Michael W Mather, Lauren Beck, Andrew Nelson, Pawel Palmowski, Andrew Porter, Jonathan Coxhead, Ann Hedley, Jonathan Scott, Anthony J Rostron, Thomas P Hellyer, Fatima Zaidi, Tracey Davey, James P Garnett, Rachel Agbeko, Chris Ward, Christopher J Stewart, Clifford C Taggart, Malcolm Brodlie, A John Simpson

Publikováno v: Powell, J, Powell, S, Mather, M W, Beck, L, Nelson, A, Palmowski, P, Porter, A, Coxhead, J, Hedley, A, Scott, J, Rostron, A J, Hellyer, T P, Zaidi, F, Davey, T, Garnett, J P, Agbeko, R, Ward, C, Stewart, C J, Taggart, C C, Brodlie, M & Simpson, A J 2023, ' Tracheostomy in children is associated with neutrophilic airway inflammation ', Thorax . https://doi.org/10.1136/thorax-2022-219557

BackgroundTracheostomies in children are associated with significant morbidity, poor quality of life, excess healthcare costs and excess mortality. The underlying mechanisms facilitating adverse respiratory outcomes in tracheostomised children are po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc47962a591c031d000e0955dcefc3d1
https://doi.org/10.1136/thorax-2022-219557

Clearance of senescent cells following cardiac ischemia-reperfusion injury improves recovery

Autor: David J. Grieve, James Chapman, Gavin D. Richardson, Emily Dookun, Anna Walaszczyk, Eleanor K Gill, Helen M. Arthur, Rachael Redgrave, Eduard Jirkovsky, Oliver E Yausep, Averina Suwana, Pawel Palmowski, Yohan Santin, Michael J. Taggart, Leticia Donastorg Sosa, Simon Tual-Chalot, João F. Passos, Jeanne Mialet-Perez, Ioakim Spyridopoulos, W. Andrew Owens

A key component of cardiac ischemia-reperfusion injury (IRI) is the increased generation of reactive oxygen species, leading to enhanced inflammation and tissue dysfunction in patients following intervention for myocardial infarction. In this study w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e85576f8a9fb70cbfafcc3b50b033bb

Depletion of Myofibril-Associated Proteins Using Selective Protein Extraction as a Tool in Cardiac Proteomics

Autor: Michael J. Taggart, G. Nicholas Europe-Finner, Pawel Palmowski, Julie Taggart, Achim Treumann, Nick Morrice, Wing Chiu Tong

Publikováno v: Methods in Molecular Biology ISBN: 9781493978526

Muscle tissue poses a particular challenge to proteomic analysis due to a very wide range of protein abundances arising from the dominant expression of myofilament-related proteins. We address this issue by describing proteomic analysis with liquid c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::466a95dfec19a2f1462aa7d7ae506e4d
https://doi.org/10.1007/7651_2017_73