Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paween Mahinthichaichan"'
Publikováno v:
JACS Au, Vol 1, Iss 12, Pp 2208-2215 (2021)
Externí odkaz:
https://doaj.org/article/ccadad67c2ea4d6cb3717ed13f1dd8d9
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Structures of mu-opioid receptor (mOR) in complex with morphine derivatives have been determined; but the structural basis of mOR activation by fentanyl-like synthetic opioids remains unclear. Here, authors use state-of-the-art simulation techniques
Externí odkaz:
https://doaj.org/article/d6525e7321244607a119714580e78d1a
Publikováno v:
ACS Omega, Vol 5, Iss 21, Pp 12016-12026 (2020)
Externí odkaz:
https://doaj.org/article/a290dcbf4b9b4a1981c28b618607abf1
Autor:
Fraser J. Moss, Paween Mahinthichaichan, David T. Lodowski, Thomas Kowatz, Emad Tajkhorshid, Andreas Engel, Walter F. Boron, Ardeschir Vahedi-Faridi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Xenopus oocytes expressing human aquaporin-7 (AQP7) exhibit greater osmotic water permeability and 3H-glycerol uptake vs. those expressing the bacterial glycerol facilitator GlpF. AQP7-expressing oocytes exposed to increasing extracellular [glycerol]
Externí odkaz:
https://doaj.org/article/35f03b2c1ad74f409cf1ec7994cffeba
Autor:
Paween Mahinthichaichan, Ruibin Liu, Quynh N. Vo, Christopher R. Ellis, Lidiya Stavitskaya, Jana Shen
Publikováno v:
J Chem Inf Model
The nation’s opioid overdose deaths reached an all-time high in 2021. The majority of deaths are due to synthetic opioids represented by fentanyl. Naloxone, which is a FDA-approved reversal agent, antagonizes opioids through competitive binding at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fbd23f7f4cee63b262791b88ea486c
https://doi.org/10.1021/acs.jcim.3c00069
https://doi.org/10.1021/acs.jcim.3c00069
Autor:
Joseph Clayton, Vinícius Martins de Oliveira, Mohamed Fouad Ibrahim, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen, Rolf Hilgenfeld, Jana Shen
Publikováno v:
Journal of Chemical Information and Modeling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf01626351ddb3ae4c313f5baf2de7e
https://doi.org/10.1021/acs.jcim.3c00344
https://doi.org/10.1021/acs.jcim.3c00344
Autor:
Paween Mahinthichaichan, Ruibin Liu, Quynh N Vo, Christopher R Ellis, Lidiya Stavitskaya, Jana Shen
Publikováno v:
bioRxiv
The nation's opioid overdose deaths reached an all-time high in 2021. The majority of deaths are due to synthetic opioids represented by fentanyl. Naloxone, which is an FDA-approved reversal agent, antagonizes opioids through competitive binding at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f13a007ff31221d9315fb79f958b814
https://doi.org/10.1101/2023.03.06.531338
https://doi.org/10.1101/2023.03.06.531338
Publikováno v:
JACS Au
JACS Au, Vol 1, Iss 12, Pp 2208-2215 (2021)
JACS Au, Vol 1, Iss 12, Pp 2208-2215 (2021)
Driven by illicit fentanyl, opioid related deaths have reached the highest level in 2020. Currently, an opioid overdose is resuscitated by the use of naloxone, which competitively binds and antagonizes the μ-opioid receptor (mOR). Thus, knowledge of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df4e995bf91173b227f30a77be64f27
https://doi.org/10.1021/jacsau.1c00341
https://doi.org/10.1021/jacsau.1c00341
Autor:
Joseph Clayton, Vinicius Martins de Oliveira, Mohamed Fouad Ibraham, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen, Rolf Hilgenfeld, Jana Shen
Nirmatrelvir is an orally available inhibitor of SARS-CoV-2 main protease (Mpro) and the main ingredient of PAXLOVID, a drug approved by FDA for high-risk COVID-19 patients. Recently, a rare natural mutation, H172Y, was found to significantly reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb9c5be606d3c460517d16d35872bf1
https://doi.org/10.1101/2022.07.31.502215
https://doi.org/10.1101/2022.07.31.502215
Publikováno v:
ACS Omega, Vol 5, Iss 21, Pp 12016-12026 (2020)
ACS Omega
ACS Omega
Electrical signals are increasingly used in fabrication of hydrogels (e.g., based on aminopolysaccharide chitosan) to guide the emergence of complex and anisotropic structure; however, how an imposed electric field affects the polymer chain conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09d5a008b8adf21d815d66ca0919d77
https://doaj.org/article/a290dcbf4b9b4a1981c28b618607abf1
https://doaj.org/article/a290dcbf4b9b4a1981c28b618607abf1