Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paweł Georgiev"'
Publikováno v:
Journal of Chromatography A. 1698:463981
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 77:69-76
Autor:
Szymon Ulenberg, Krzesimir Ciura, Paweł Georgiev, Monika Pastewska, Grzegorz Ślifirski, Marek Król, Franciszek Herold, Tomasz Bączek
Publikováno v:
Microchemical Journal. 175:107183
Autor:
Paweł Georgiev, Szymon Ulenberg, Marek Król, Tomasz Bączek, Andrzej Chodkowski, Franciszek Herold, Mariusz Belka, Grzegorz Ślifirski, Martyna Z. Wróbel
Publikováno v:
Journal of chromatography. A. 1629
Metabolic stability tests are one of the fundamental steps at the preclinical stages of new drug development. Microsomes, used as a typical enzymatic model of liver biotransformation, can be a challenging matrix for analytical scientists due to a hig
Autor:
Szymon Ulenberg, Piotr Kawczak, Wiesław Sawicki, Barbara Bednarczyk-Cwynar, Paweł Georgiev, Krzesimir Ciura, Hanna Kapica, Natalia Buławska, Tomasz Bączek, Strahinja Z. Kovačević, Monika Pastewska
Publikováno v:
Journal of Chromatography A. 1656:462552
Naturally occurring molecules are excellent sources of lead compounds. A series of oleanolic acid (OA) derivatives previously synthesized in our laboratory, which show promising antitumor activity, have been analyzed in terms of lipophilicity evaluat
Autor:
Grzegorz Ślifirski, Marek Król, Franciszek Herold, Szymon Ulenberg, Tomasz Bączek, Mariusz Belka, Paweł Georgiev
Publikováno v:
Microchemical Journal. 159:105550
Metabolic stability plays a crucial role in assessing the safety of potential drug candidates. Assays to designate in vitro half-life are well established and are focused on phase I metabolism using human liver microsomes. However, such an assay can