Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pawan Nandakishore"'
Autor:
Vinita Bharat, Aarooran S. Durairaj, Roeland Vanhauwaert, Li Li, Colin M. Muir, Sujyoti Chandra, Chulhwan S. Kwak, Yann Le Guen, Pawan Nandakishore, Chung-Han Hsieh, Stefano E. Rensi, Russ B. Altman, Michael D. Greicius, Liang Feng, Xinnan Wang
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113544- (2023)
Summary: Dysregulated iron or Ca2+ homeostasis has been reported in Parkinson’s disease (PD) models. Here, we discover a connection between these two metals at the mitochondria. Elevation of iron levels causes inward mitochondrial Ca2+ overflow, th
Externí odkaz:
https://doaj.org/article/d232850709d248d9838e814e06aa9ca2
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
There is a lack of reliable molecular markers for Parkinson’s disease (PD) patients and at-risk individuals. The detection of the pre-symptomatic population of PD will empower more effective clinical intervention to delay or prevent disease onset.
Externí odkaz:
https://doaj.org/article/643cebd46ffc4c8e86443b9173a60e8e
Autor:
Vinita Bharat, Roeland Vanhauwaert, Li Li, Colin M. Muir, Aarooran Sivakumaran Durairaj, Sujyoti Chandra, Yann Le Guen, Pawan Nandakishore, Chung-Han Hsieh, Stefano E. Rensi, Russ B. Altman, Michael D. Greicius, Liang Feng, Xinnan Wang
SummaryGenetic backgrounds and risk factors among individuals with Parkinson’s disease (PD) are highly heterogenous, limiting our ability to effectively detect and treat PD. Here we connect several potential PD risk genes and elements to one biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fa9d116fea8e0e315ce47a47b7de7fd
https://doi.org/10.1101/2022.10.30.513580
https://doi.org/10.1101/2022.10.30.513580
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
There is a lack of reliable molecular markers for Parkinson’s disease (PD) patients and at-risk individuals. The detection of the pre-symptomatic population of PD will empower more effective clinical intervention to delay or prevent disease onset.
Autor:
Lucas Goehring, Pawan Nandakishore
Publikováno v:
Soft Matter
Cracks in thin layers are influenced by what lies beneath them. From buried craters to crocodile skin, crack patterns are found over an enormous range of length scales. Regardless of absolute size, their substrates can dramatically influence how crac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6d644815704da4af0014e96d28ec43
https://hdl.handle.net/11858/00-001M-0000-0029-BBA1-0
https://hdl.handle.net/11858/00-001M-0000-0029-BBA1-0