Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Pavol Szabo"'
Autor:
Václav Mandys, Alexey Popov, Robert Gürlich, Jan Havránek, Lucie Pfeiferová, Michal Kolář, Jana Vránová, Karel Smetana, Lukáš Lacina, Pavol Szabo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3617 (2023)
Therapy for pancreatic ductal adenocarcinoma remains challenging, and the chances of a complete cure are very limited. As in other types of cancer, the expression and role of miRNAs in controlling the biological properties of this type of tumor have
Externí odkaz:
https://doaj.org/article/1160c0a5380240249736e2e8622f2329
Autor:
Michal Španko, Karolína Strnadová, Aleš Jan Pavlíček, Pavol Szabo, Ondřej Kodet, Jaroslav Valach, Barbora Dvořánková, Karel Smetana, Lukáš Lacina
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11027 (2021)
Interleukin-6 (IL-6) is a highly potent cytokine involved in multiple biological processes. It was previously reported to play a distinct role in inflammation, autoimmune and psychiatric disorders, ageing and various types of cancer. Furthermore, it
Externí odkaz:
https://doaj.org/article/56c0657f5723488bb47573ce8dbad148
Autor:
Matúš Čoma, Lucia Fröhlichová, Lukáš Urban, Robert Zajíček, Tomáš Urban, Pavol Szabo, Štěpán Novák, Vitaly Fetissov, Barbora Dvořánková, Karel Smetana, Peter Gál
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 897 (2021)
Excessive connective tissue accumulation, a hallmark of hypertrophic scaring, results in progressive deterioration of the structure and function of organs. It can also be seen during tumor growth and other fibroproliferative disorders. These processe
Externí odkaz:
https://doaj.org/article/823f2d6f07f046f99df0aba4b1f4ba87
Autor:
Jan Brábek, Milan Jakubek, Fréderic Vellieux, Jiří Novotný, Michal Kolář, Lukáš Lacina, Pavol Szabo, Karolína Strnadová, Daniel Rösel, Barbora Dvořánková, Karel Smetana
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7937 (2020)
Interleukin-6 (IL-6) is a cytokine with multifaceted effects playing a remarkable role in the initiation of the immune response. The increased level of this cytokine in the elderly seems to be associated with the chronic inflammatory setting of the m
Externí odkaz:
https://doaj.org/article/1d24d40f70c944c99965f9d23783e75a
Autor:
Ivan Kováč, Nikola Melegová, Matúš Čoma, Peter Takáč, Katarína Kováčová, Martin Hollý, Ján Ďurkáč, Lukáš Urban, Miriam Gurbáľová, Emil Švajdlenka, Gabriela Mojžišová, Robert Zajíček, Pavol Szabo, Pavel Mučaji, Peter Gál
Publikováno v:
Molecules, Vol 25, Iss 8, p 1917 (2020)
The ability of horse chestnut extract (HCE) to induce contraction force in fibroblasts, a process with remarkable significance in skin repair, motivated us to evaluate its wound healing potential in a series of experiments. In the in vitro study of t
Externí odkaz:
https://doaj.org/article/e81f67becdab4c91aaa473b723ea3211
Autor:
Lukas Lacina, Jan Plzak, Ondrej Kodet, Pavol Szabo, Martin Chovanec, Barbora Dvorankova, Karel Smetana Jr.
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 24094-24110 (2015)
Epidermal stem cells (ESCs) are crucial for maintenance and self- renewal of skin epithelium and also for regular hair cycling. Their role in wound healing is also indispensable. ESCs reside in a defined outer root sheath portion of hair follicle—a
Externí odkaz:
https://doaj.org/article/6f7eacf93be142f29c3a94765eaa4ee5
Autor:
Peter Gál, Lenka Varinská, Lenka Fáber, Štepán Novák, Pavol Szabo, Petra Mitrengová, Andrej Mirossay, Pavel Mučaji, Karel Smetana
Publikováno v:
Molecules, Vol 22, Iss 11, p 1818 (2017)
It is now suggested that the inhibition of biological programs that are associated with the tumor microenvironment may be critical to the diagnostics, prevention and treatment of cancer. On the other hand, a suitable wound microenvironment would acce
Externí odkaz:
https://doaj.org/article/95d7b2a715664ef3a6912aa2ac291dcd
Autor:
TOMÁŠ VASILENKO, IVAN KOVÁČ, MARTIN SLEZÁK, JÁN ĎURKÁČ, VLASTA PERŽEL’OVÁ, MATÚŠ ČOMA, MIRIAM KAŇUCHOVÁ, LUKÁŠ URBAN, PAVOL SZABO, BARBORA DVOŘÁNKOVÁ, ANDREJ VRZGULA, ROBERT ZAJÍČEK, KAREL SMETANA, PETER GÁL
Publikováno v:
In Vivo
Background/Aim: We have previously shown that the water extract of Agrimonia eupatoria L. (AE) is a valuable source of polyphenols with excellent antioxidant properties and has clinical potential for the prevention and/or adjuvant therapy of cardiova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7277aed9285e35f85d93c0bfd5c3e494
https://europepmc.org/articles/PMC9087068/
https://europepmc.org/articles/PMC9087068/
Autor:
Nikola Melegová, Matúš Čoma, Lukáš Urban, Miriam Kaňuchová, Pavol Szabo, Karel Smetana Jr., Pavel Mučaji, Peter Gál
Publikováno v:
Neoplasma. 69(1)
Fibroblasts are actively involved in the formation of granulation tissue and/or tumor stroma. These cells possess the potential to differentiate into myofibroblasts acquiring a highly contractile phenotype characterized by the expression of α-smooth