Analysis of the Spectrum of ACE2 Variation Suggests a Possible Influence of Rare and Common Variants on Susceptibility to COVID-19 and Severity of Outcome.

Autor: Shikov AE; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia.; Saint Petersburg State University, Saint Petersburg, Russia., Barbitoff YA; Saint Petersburg State University, Saint Petersburg, Russia.; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia.; Bioinformatics Institute, Saint Petersburg, Russia., Glotov AS; Saint Petersburg State University, Saint Petersburg, Russia.; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Danilova MM; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Tonyan ZN; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Nasykhova YA; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Mikhailova AA; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Bespalova ON; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Kalinin RS; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Mirzorustamova AM; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Kogan IY; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Baranov VS; Saint Petersburg State University, Saint Petersburg, Russia.; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia., Chernov AN; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Pavlovich DM; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Azarenko SV; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Fedyakov MA; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Tsay VV; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Eismont YA; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Romanova OV; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Hobotnikov DN; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Vologzhanin DA; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Mosenko SV; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Ponomareva TA; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Talts YA; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Anisenkova AU; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Lisovets DG; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Sarana AM; Saint Petersburg State University, Saint Petersburg, Russia., Urazov SP; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia., Scherbak SG; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia.; Saint Petersburg State University, Saint Petersburg, Russia., Glotov OS; Genetics Laboratory, City Hospital No. 40, Saint Petersburg, Russia.; Department of Genomic Medicine, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia.

Publikováno v: Frontiers in genetics [Front Genet] 2020 Sep 29; Vol. 11, pp. 551220. Date of Electronic Publication: 2020 Sep 29 (Print Publication: 2020).