Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pavlos Neophytou"'
Autor:
Joseph Z. Zaretsky, Michael A. McGuckin, Pavlos Neophytou, His-Hsien Lin, Merav Yoeli, Iafa Keydar, Stefanie J. Williams, Ravit Ziv, Amos Baruch, Daniel H. Wreschner, Martin Stacey, Nechama I. Smorodinsky, Siamon Gordon, Liron Okun
Publikováno v:
Protein Science. 11:698-706
A mechanism is described whereby one and the same gene can encode both a receptor protein as well as its specific ligand. Generation of this receptor-ligand partnership is effected by proteolytic cleavage within a specific module located in a membran
Autor:
Ioanna Zouvani, Kyriacos Kyriacou, Christoforos Stavrou, Corinne Antignac, Pavlos Neophytou, Constantinos Deltas, Kyproula Christodoulou, Alkis Pierides
Publikováno v:
American Journal of Medical Genetics. 77:149-154
We describe a large Cypriot family with an interstitial type of nephropathy, inherited as an autosomal dominant trait that led to end stage renal failure between 51 to 78 years of age (mean 62.2 years). Twenty-three people are known to be affected, b
Autor:
John C. Hutton, Pavlos Neophytou, Gaby Duinkerken, A. A. Kallan, Susan D. Arden, Bart O. Roep, R. R. P. De Vries, E. M. Muir
Publikováno v:
Proceedings of the National Academy of Sciences. 93:2014-2018
Studies on circulating T cells and antibodies in newly diagnosed type 1 diabetic patients and rodent models of autoimmune diabetes suggest that beta-cell membrane proteins of 38 kDa may be important molecular targets of autoimmune attack. Biochemical
Publikováno v:
Diabetes. 45:127-133
A polymerase chain reaction-based subtractive hybridization procedure was applied to cDNAs prepared from mouse insulinoma (beta TC3) and glucagonoma (alpha TC2) cell lines to construct a library of cDNAs that are highly expressed in pancreatic beta-c
Autor:
Susan D. Arden, Gaby Duinkerken, R. R. P. De Vries, Bart O. Roep, E. F. Usac, John C. Hutton, Pavlos Neophytou
Publikováno v:
Journal of Clinical Investigation. 97:551-561
Cell-mediated autoimmune attack directed against islet proteins of approximately 38 kD in size has been associated with type 1 diabetes. A novel murine cDNA encoding an antigen of this size was cloned using a screening procedure based on the prolifer
Autor:
John C. Hutton, Patricia Ozegbe, Donald G. Healey, Pavlos Neophytou, Ruby Quartey-Papafio, Anne Cooke
Publikováno v:
Journal of Immunological Methods. 196:63-72
Although single bacterial recombinant antigens have been used successfully to stimulate individual T-cell clones and elicit recall responses in peripheral lymphocytes, the broader use of molecular cloning systems for the identification of autoantigen
Autor:
Alex E. Felice, Andrea Novelletto, A. Berebbi, Vincenzo Lorenzo Pascali, Valérie Delague, André Mégarbané, David Goldstein, Pavlos Neophytou, Nicola Redhead, Gérard Lefranc, Patrizia Malaspina, Marc Fellous, L. Terrenato, Mark G. Thomas, Valentino Romano, Cristian Capelli, Z. Poulli, Filippo Cali
Publikováno v:
Annals of Human Genetics
Annals of Human Genetics, Wiley, 2006, 70, pp.207-225. ⟨10.1111/j.1529-8817.2005.00224.x⟩
Annals of Human Genetics, Wiley, 2006, 70, pp.207-225. ⟨10.1111/j.1529-8817.2005.00224.x⟩
The Mediterranean region has been characterised by a number of pre-historical and historical demographic events whose legacy on the current genetic landscape is still a matter of debate. In order to investigate the degree of population structure acro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b44c7388d4153fd77ae10274ca2a59
https://hal.archives-ouvertes.fr/hal-00082362
https://hal.archives-ouvertes.fr/hal-00082362
Publikováno v:
Hansen, S, Lo, B, Evans, K, Neophytou, P, Holmskov, U & Wright, J R 2006, ' Surfactant protein D augments bacterial association but attenuates major histocompatibility complex class II presentation of bacterial antigens ', American Journal of Respiratory Cell and Molecular Biology, vol. 36, no. 1, pp. 94-102 . https://doi.org/10.1165/rcmb.2006-0195OC
Surfactant protein D (SP-D) is a secreted pattern recognition molecule associated with lung surfactant and mediates the clearance of pathogens in multiple ways. SP-D is an established part of the innate immune system, but it also modulates the adapti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ff09691e0d037f1ce810562208e1d3
https://portal.findresearcher.sdu.dk/da/publications/db4b4050-fe6b-11dc-86ef-000ea68e967b
https://portal.findresearcher.sdu.dk/da/publications/db4b4050-fe6b-11dc-86ef-000ea68e967b
Autor:
Zvi Fireman, Eitan Friedman, Shiri Dovrat, Arie Figer, Ravit Geva, Dov Flex, Herma H. Fidder, Shimon Bar Meir, Pavlos Neophytou, Jamal Zidan
Publikováno v:
Familial cancer. 4(4)
Germline mutations in DNA mismatch repair (DNA-MMR) genes, mainly hMlh1 and hMsh2, underlie Hereditary Non-Polyposis Colorectal Cancer (HNPCC). Germline hMSH6 gene mutations have been reported in a small subset of HNPCC families. In the present study
Autor:
Shiri Dovrat, Arie Figer, Herma Fidder, Pavlos Neophytou, Zvi Fireman, Ravit Geva, Jamal Zidan, Dov Flex, Shimon Meir, Eitan Friedman
Publikováno v:
Familial Cancer; Nov2005, Vol. 4 Issue 4, p291-294, 4p