Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Pavlos, Msaouel"'
Autor:
Mihir D. Shanker, Zhiqian Henry Yu, Jinzhong Yang, Surena Matin, Matthew T. Campbell, Pavlos Msaouel, Nizar Tannir, Surendra Prajapati, Yao Ding, Belinda Lee, Angela Sobremonte, Chad Tang
Publikováno v:
BJUI Compass, Vol 5, Iss 10, Pp 913-915 (2024)
Externí odkaz:
https://doaj.org/article/ec3fbc5de47645f68d5c19768cea6592
Autor:
Mohammad Jad Moussa, Jaanki Khandelwal, Nathaniel R. Wilson, Sagar A. Naik, Vivek Subbiah, Matthew T. Campbell, Pavlos Msaouel, Parminder Singh, Omar Alhalabi
Publikováno v:
Current Oncology, Vol 31, Iss 6, Pp 3342-3349 (2024)
Small cell bladder cancer (SCBC) is a rare and aggressive disease, often treated with platinum/etoposide-based chemotherapy. Key molecular drivers include the inactivation of onco-suppressor genes (TP53, RB1) and amplifications in proto-oncogenes (MY
Externí odkaz:
https://doaj.org/article/bbb72ef7a31447418f0648f931ce0d61
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Background Immune checkpoint inhibitors (ICIs) have significantly improved outcomes for patients with cancer. However, these therapies are associated with adverse events including de novo immune-related adverse events or flare of pre-exiting autoimmu
Externí odkaz:
https://doaj.org/article/645c7485a5394d94a0b9d241c919f74f
Autor:
Pavlos Msaouel, Ramez Kouzy, Joseph Abi Jaoude, Ethan B Ludmir, Alexander D Sherry, Timothy A Lin, Esther J Beck, Avital M Miller, Adina H Passy, Gabrielle S Kupferman, Eugene J Koay, Clifton David Fuller, Charles R Thomas, Zachary R McCaw
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Estimations of the treatment effect on overall survival (OS) may be influenced by post-progression therapies (PPTs). It is unclear how often OS analyses account for PPT effects. The purpose of this cross-sectional analysis was to determine
Externí odkaz:
https://doaj.org/article/284718e1663b466c99a570c4fdc80d03
Autor:
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J. H. Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J. Ellis, Andrea B. Apolo, Leomar Y. Ballester, Jianjun Gao, Donna E. Hansel, Yair Lotan, H. Courtney Hodges, Seth P. Lerner, Chad J. Creighton, Arun Sreekumar, W. Jim Zheng, Pavlos Msaouel, Shyam M. Kavuri, Nagireddy Putluri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract SMARCB1 loss has long been observed in many solid tumors. However, there is a need to elucidate targetable pathways driving growth and metastasis in SMARCB1-deficient tumors. Here, we demonstrate that SMARCB1 deficiency, defined as genomic S
Externí odkaz:
https://doaj.org/article/92dacc4a9b18472087b40b7343faadf4
Autor:
Pavlos Msaouel
Publikováno v:
Harvard Data Science Review, Vol 6, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/1ce82a45a38d4ea4823fb2e4abc35d2e
Autor:
J. Bryan Iorgulescu, Leah K. Shaw, Asif Rashid, Priya Rao, Sreedhar Mandayam, Keyur P. Patel, Kathleen M. Schmeler, Richard K. Yang, Pavlos Msaouel
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 9019-9027 (2023)
Clear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type cle
Externí odkaz:
https://doaj.org/article/d574c19ba193436980ddfb595b27cbbc
Autor:
Wei Shen Tan, Valentina Grajales, Roberto Contieri, Patrick Hensley, Kelly Bree, Pavlos Msaouel, Charles C. Guo, Graciela M. Nogueras-Gonzalez, Neema Navai, Colin P. Dinney, Ashish M. Kamat
Publikováno v:
European Urology Open Science, Vol 53, Iss , Pp 16-22 (2023)
Background: Data for bladder-sparing treatment (BST) in bacillus Calmette-Guerin (BCG)-unresponsive non–muscle-invasive bladder cancer (NMIBC) patients report short-term outcomes limited to 1–2 yr. Objective: To assess long-term survival outcomes
Externí odkaz:
https://doaj.org/article/bc22d6eb975b4372ba604d04c4bfd745
Autor:
Iuliia Kovalenko, Wern Lynn Ng, Yimin Geng, Yinghong Wang, Pavlos Msaouel, Shailender Bhatia, Petros Grivas, Raed Benkhadra, Omar Alhalabi
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundCombining immune checkpoint therapy (ICT) and vascular endothelial growth factor inhibitors (VEGFi) may result in increased treatment-related and immune-related adverse events (TRAEs and irAEs) compared to ICT alone. This metanalysis was co
Externí odkaz:
https://doaj.org/article/8f899d84a5f44098932e9c01eeae5121
Autor:
Bujamin H. Vokshi, Guillaume Davidson, Nassim Tawanaie Pour Sedehi, Alexandra Helleux, Marc Rippinger, Alexandre R. Haller, Justine Gantzer, Jonathan Thouvenin, Philippe Baltzinger, Rachida Bouarich, Valeria Manriquez, Sakina Zaidi, Priya Rao, Pavlos Msaouel, Xiaoping Su, Hervé Lang, Thibault Tricard, Véronique Lindner, Didier Surdez, Jean-Emmanuel Kurtz, Franck Bourdeaut, Nizar M. Tannir, Irwin Davidson, Gabriel G. Malouf
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Renal medullary carcinoma (RMC) is an aggressive tumour driven by bi-allelic loss of SMARCB1 and tightly associated with sickle cell trait. However, the cell-of-origin and oncogenic mechanism remain poorly understood. Using single-cell seque
Externí odkaz:
https://doaj.org/article/01f90a34514d4d2a88792568e2a609ad