Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Pavlo Holenya"'
Immune profiling of SARS-CoV-2 epitopes in asymptomatic and symptomatic pediatric and adult patients
Autor:
Anna Lucia Tornesello, Chiara Botti, Alberto Micillo, Francesco Labonia, Sergio Arpino, Maria Antonietta Isgrò, Serena Meola, Luigi Russo, Ernesta Cavalcanti, Silvia Sale, Carmine Nicastro, Luigi Atripaldi, Noemy Starita, Andrea Cerasuolo, Ulf Reimer, Pavlo Holenya, Luigi Buonaguro, Franco M. Buonaguro, Maria Lina Tornesello
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has unpredictable manifestations of coronavirus disease (COVID-19) and variable clinical course with some patients being asymptomatic whereas others e
Externí odkaz:
https://doaj.org/article/9f2f4a4986df497285d6a81294428b3f
Linear epitope mapping of the humoral response against SARS-CoV-2 in two independent African cohorts
Autor:
Inès Vigan-Womas, Jean-Louis Spadoni, Thomas Poiret, Fabien Taïeb, Fanirisoa Randrianarisaona, Rokhaya Faye, Adji Astou Mbow, Aboubacry Gaye, Ndongo Dia, Cheikh Loucoubar, Diary Juliannie Ny Mioramalala, Rila Ratovoson, Rindra Vatosoa Randremanana, Amadou Alpha Sall, Moussa Seydi, Josselin Noirel, Gabriel Moreau, Arnaud Simon, Pavlo Holenya, Jean-Philippe Meyniel, Jean-François Zagury, Matthieu Schoenhals
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Profiling of the antibody responses to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) proteins in African populations is scarce. Here, we performed a detailed IgM and IgG epitope mapping study against 487 peptides covering SARS
Externí odkaz:
https://doaj.org/article/2b5c09a85a5e4c7b991d9190800027ff
Autor:
Larissa Henze, Julian Braun, Lil Meyer-Arndt, Karsten Jürchott, Maike Schlotz, Janine Michel, Marica Grossegesse, Maike Mangold, Manuela Dingeldey, Beate Kruse, Pavlo Holenya, Norbert Mages, Ulf Reimer, Maren Eckey, Karsten Schnatbaum, Holger Wenschuh, Bernd Timmermann, Florian Klein, Andreas Nitsche, Claudia Giesecke-Thiel, Lucie Loyal, Andreas Thiel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Currently available COVID-19 vaccines include inactivated virus, live attenuated virus, mRNA-based, viral vectored and adjuvanted protein-subunit-based vaccines. All of them contain the spike glycoprotein as the main immunogen and result in reduced d
Externí odkaz:
https://doaj.org/article/8d30110c924e4be5beac3a8eb0a4da1f
Autor:
Adéla Nacer, Gaily Kivi, Raini Pert, Erkki Juronen, Pavlo Holenya, Eduardo Aliprandini, Rogerio Amino, Olivier Silvie, Doris Quinkert, Yann Le Duff, Matthew Hurley, Ulf Reimer, Andres Tover, Simon J. Draper, Sarah Gilbert, Mei Mei Ho, Paul W. Bowyer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria, an infection caused by apicomplexan parasites of the genus Plasmodium, continues to exact a significant toll on public health with over 200 million cases world-wide, and annual deaths in excess of 600,000. Considerable progress has been made
Externí odkaz:
https://doaj.org/article/964ca94ca03a4486ab7310ec1cba72cb
Autor:
Zeribe Chike Nwosu, Weronika Piorońska, Nadia Battello, Andreas David Zimmer, Bedair Dewidar, Mei Han, Sharon Pereira, Biljana Blagojevic, Darko Castven, Verodia Charlestin, Pavlo Holenya, Julia Lochead, Carolina De La Torre, Norbert Gretz, Peter Sajjakulnukit, Li Zhang, Matthew H. Ward, Jens U. Marquardt, Marina Pasca di Magliano, Costas A. Lyssiotis, Jonathan Sleeman, Stefan Wölfl, Matthias Philip Ebert, Christoph Meyer, Ute Hofmann, Steven Dooley
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: The extracellular signal-regulated kinase (ERK) pathway regulates cell growth, and is hyper-activated and associated with drug resistance in hepatocellular carcinoma (HCC). Metabolic pathways are profoundly dysregulated in HCC. Whether an
Externí odkaz:
https://doaj.org/article/383d5f40c0a84df0afc5bf27b396bda2
Autor:
Madlen Loebel, Maren Eckey, Franziska Sotzny, Elisabeth Hahn, Sandra Bauer, Patricia Grabowski, Johannes Zerweck, Pavlo Holenya, Leif G Hanitsch, Kirsten Wittke, Peter Borchmann, Jens-Ulrich Rüffer, Falk Hiepe, Klemens Ruprecht, Uta Behrends, Carola Meindl, Hans-Dieter Volk, Ulf Reimer, Carmen Scheibenbogen
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179124 (2017)
Epstein-Barr-Virus (EBV) plays an important role as trigger or cofactor for various autoimmune diseases. In a subset of patients with Chronic Fatigue Syndrome (CFS) disease starts with infectious mononucleosis as late primary EBV-infection, whereby a
Externí odkaz:
https://doaj.org/article/32d2f45d63e640d198c3403d6eddd8e3
Autor:
Hamed Alborzinia, Suzan Can, Pavlo Holenya, Catharina Scholl, Elke Lederer, Igor Kitanovic, Stefan Wölfl
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19714 (2011)
Since the discovery of cisplatin more than 40 years ago and its clinical introduction in the 1970s an enormous amount of research has gone into elucidating the mechanism of action of cisplatin on tumor cells. With a novel cell biosensor chip system a
Externí odkaz:
https://doaj.org/article/496faa8e06dc40e1b47cdef474b3182c
Autor:
Lil Meyer-Arndt, Julian Braun, Florent Fauchere, Kanika Vanshylla, Lucie Loyal, Larissa Henze, Beate Kruse, Manuela Dingeldey, Karsten Jürchott, Maike Mangold, Ardit Maraj, Andre Braginets, Chotima Böttcher, Andreas Nitsche, Kathrin de la Rosa, Christoph Ratswohl, Birgit Sawitzki, Pavlo Holenya, Ulf Reimer, Leif E Sander, Florian Klein, Friedemann Paul, Judith Bellmann-Strobl, Andreas Thiel, Claudia Giesecke-Thiel
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:960-971
BackgroundSARS-CoV-2 mRNA vaccination of healthy individuals is highly immunogenic and protective against severe COVID-19. However, there are limited data on how disease-modifying therapies (DMTs) alter SARS-CoV-2 mRNA vaccine immunogenicity in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79faea54a91f7c0fb58b5f142b6b94ca
https://doi.org/10.1136/jnnp-2022-329395
https://doi.org/10.1136/jnnp-2022-329395
Autor:
Lil Meyer-Arndt, Julian Braun, Florent Fauchere, Kanika Vanshylla, Lucie Loyal, Larissa Henze, Beate Kruse, Manuela Dingeldey, Karsten Jürchott, Maike Mangold, Ardit Maraj, Andre Braginets, Chotima Böttcher, Andreas Nitsche, Kathrin de la Rosa, Christoph Ratswohl, Birgit Sawitzki, Pavlo Holenya, Ulf Reimer, Leif E. Sander, Florian Klein, Friedemann Paul, Judith Bellmann-Strobl, Andreas Thiel, Claudia Giesecke-Thiel
SARS-CoV-2 mRNA vaccination of healthy individuals is highly immunogenic and protective against severe COVID-19. However, there are limited data on how disease-modifying therapies (DMTs) alter SARS-CoV-2 mRNA vaccine immunogenicity in patients with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::335124eccd0a4d729d9dc9e95faf573f
https://doi.org/10.1101/2022.02.06.22270550
https://doi.org/10.1101/2022.02.06.22270550
Autor:
Luigi Buonaguro, Anna Lucia Tornesello, Franco M. Buonaguro, Tobias Knaute, Maria Lina Tornesello, Angelo Salomone Megna, Francesca Pezzuto, Francesco Izzo, Pavlo Holenya, Ulf Reimer
Background: Chronic infection with hepatitis C virus (HCV) is among the major causes of hepatic fibrosis, cirrhosis, as well as hepatocellular carcinoma (HCC), and it is associated with a significant risk of developing lymphoproliferative disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8227b6f40cd8796ac0b13f860aea1ab