Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pavlina Chrysafi"'
Total and H-specific GDF-15 levels increase in caloric deprivation independently of leptin in humans
Autor:
Pavlina Chrysafi, Laura Valenzuela-Vallejo, Konstantinos Stefanakis, Theodoros Kelesidis, Margery A. Connelly, Christos S. Mantzoros
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Mitochondrial-secreted growth differentiation factor-15 (GDF-15) promotes weight loss in animals. Its effects in humans remain unclear, due to limited research and potential measurement interference from the H202D-variant. Our post-hoc analy
Externí odkaz:
https://doaj.org/article/2a257a3c2a054b439cb7d365ab7cffef
Autor:
Pavlina Chrysafi, Nikolaos Perakakis, Olivia M. Farr, Konstantinos Stefanakis, Natia Peradze, Aleix Sala-Vila, Christos S. Mantzoros
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Leptin treatment is effective to reduce body weight in animal models, but patients with obesity and associated hyperleptinemia do not respond well to leptin therapy. Here the authors report a retrospective analysis of four clinical trials in normo- a
Externí odkaz:
https://doaj.org/article/84158d742bc143a7890d54e03f2e13a8
Publikováno v:
Metabolism. 142:155443
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34412268220eb2dd07f3443eaebb127e
https://doi.org/10.1016/j.metabol.2023.155443
https://doi.org/10.1016/j.metabol.2023.155443
Publikováno v:
Metabolism. 142:155444
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84e6f7793985fd7de5de4a4e6ddb492a
https://doi.org/10.1016/j.metabol.2023.155444
https://doi.org/10.1016/j.metabol.2023.155444
Autor:
Laura Valenzuela-Vallejo, Pavlina Chrysafi, Valentina Guatibonza-García, Chrysoula Boutari, Melih Agraz, Margery A. Connelly, George V. Papatheodoridis, Ornella Verrastroe, Geltrude Mingrone, Christos S. Mantzoros
Publikováno v:
Metabolism. 142:155445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc6c09f28034e502247da65eb609952
https://doi.org/10.1016/j.metabol.2023.155445
https://doi.org/10.1016/j.metabol.2023.155445
Publikováno v:
Diabetesmetabolism. 48(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf28c42b6e1b9f53519a02f30baaac55
https://pubmed.ncbi.nlm.nih.gov/35777691
https://pubmed.ncbi.nlm.nih.gov/35777691
Autor:
Laura Valenzuela-Vallejo, Pavlina Chrysafi, Jenny Bello-Ramos, Shahd Bsata, Christos S. Mantzoros
Publikováno v:
Metabolism: clinical and experimental. 133
Growth differentiation factor 15 (GDF-15) is a stress-response cytokine proposed to be associated with body weight regulation.The primary aim was to investigate changes of circulating intact GDF-15 (wildtype, non-carrier of the rs1058587 polymorphism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f137b2930181422849be0b55ff66d9f2
https://pubmed.ncbi.nlm.nih.gov/35700837
https://pubmed.ncbi.nlm.nih.gov/35700837
Autor:
Nikolaos Perakakis, Christos S. Mantzoros, Pavlina Chrysafi, Michael Feigh, Sanne Skovgård Veidal
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6332, p 6332 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6332, p 6332 (2021)
Empagliflozin, an established treatment for type 2 diabetes (T2DM), has shown beneficial effects on liver steatosis and fibrosis in animals and in humans with T2DM, non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH). However, little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307be0038c4c995eceb3ed2c8e106756
Autor:
Natia Peradze, Pavlina Chrysafi, Olivia M. Farr, Konstantinos Stefanakis, Aleix Sala-Vila, Christos S. Mantzoros, Nikolaos Perakakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Based on studies in mice, leptin was expected to decrease body weight in obese individuals. However, the majority of the obese are hyperleptinemic and do not respond to leptin treatment, suggesting the presence of leptin tolerance and questioning the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c34718c340b35bf7452d20a372760e4
https://doi.org/10.1038/s41467-020-18885-9
https://doi.org/10.1038/s41467-020-18885-9
Publikováno v:
Journal of Surgical Education. 74:690-697
Modern medicine is based on teamwork and communication. Bullying and discrimination can have a serious effect on these, affecting the standard of medical training and patient care.To determine the incidence of bullying and sex discrimination in the G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6a66e9478970a0199bef0bb279e5eb
https://doi.org/10.1016/j.jsurg.2016.12.005
https://doi.org/10.1016/j.jsurg.2016.12.005