Výsledky vyhledávání - "Pavla Tejklová"

Mutation in the immunodominant epitope of the HPV16 E7 oncoprotein as a mechanism of tumor escape

Autor: Pavla Tejklová, Jana Smahelova, Michal Smahel, Jana Mackova, Ingrid Polakova

Publikováno v: Cancer Immunology, Immunotherapy. 57:823-831

Infection with high-risk types of human papillomavirus (HPV) can cause the development of malignant tumors. To study mechanisms responsible for immune escape of tumor cells infected with HPV16, we previously used mouse oncogenic TC-1 cells producing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f7f83dd037837bd022b9a434e61d90
https://doi.org/10.1007/s00262-007-0418-9

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Characterization of cell lines derived from tumors induced by TC-1 cells in mice preimmunized against HPV16 E7 oncoprotein

Autor: Michal, Smahel, Jana, Smahelová, Pavla, Tejklová, Ruth, Tachezy, Iuri, Marinov

Publikováno v: International journal of oncology. 27(3)

Escape of tumor cells from the host immune system is probably the most difficult obstacle to overcome in attempts to enhance the efficacy of immunotherapy of tumors. To solve the problem, animal models with escape mechanisms found in human tumors are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1b952148dd82d7f34974dfd42f634b7c
https://pubmed.ncbi.nlm.nih.gov/16077923

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Analysis of tumor progression by transcriptional profiling of mouse MK16 cell lines transformed with human papillomavirus type 16 E6 and E7 oncogenes and activated H-ras

Autor: Frantisek Jelínek, Michal Smahel, Jana Smahelova, Pavla Tejklová, Ruth Tachezy

Publikováno v: ResearcherID
Scopus-Elsevier
Europe PubMed Central

A better understanding of the molecular basis of tumor progression and invasion is needed to improve therapy for malignant tumors. Recently, we established a mouse metastatic MK16 model by transduction of secondary kidney cells with human papillomavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676b3cadbf8705f484a7965fe6b4647e
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000233494200043&KeyUID=WOS:000233494200043

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